Proscar use on AAS cycle?

[jlh98765]

I've researched and have read conflicting opinions of Proscar(finasteride) use while on AAS.

I'm currently using test prop and npp. I want to minimize risks with my prostate for obvious reasons.

I have Proscar. Is it benficial to run when with the cycle?

Does anyone have some good research to reference the effectiveness of using it or not while on AAS, or any first hand info.

K for good info.

 

[Joe Stick]

I've researched and have read conflicting opinions of Proscar(finasteride) use while on AAS.

I'm currently using test prop and npp. I want to minimize risks with my prostate for obvious reasons.

I have Proscar. Is it benficial to run when with the cycle?

Does anyone have some good research to reference the effectiveness of using it or not while on AAS, or any first hand info.

K for good info.

It would be better to run the proscar to protect your prostrate during your cycle. The conflicting info about deca and finasteride is that when you mix the two it can accelerate hairloss because deca doesnt get reduced to a weaker androgen by the 5 AR enzyme, but if your main concern is your prostrate then it would be better to use proscar to keep DHT levels to a minimum.

Im assuming that deca doesnt have as much effect on the prostrate as DHT would. K UP!!!

 

[eliteforce]

i used proscar (5mg finisteride) & anavar; i grew so much hair back i felt like i was 12, didn't appear to negativly affect gains, sex drive was slightly diminished but not seriously

 

[R21]

What conflicting info have you heard?

I split a (5mg) proscar tablet in 4 and take a piece (1.25mg) a day on my 500mg/week test cycle (with 40mg-4week-tbol kick start) to reduce the extra amount of DHT that occurs while on cycle. Beter safe then sorry is what I think.

Only thing you have to look for when taking finasteride, is that it can affect some people's libido (not likely on a test cycle), the chance of gyno increases as DHT is an anti-estrogen so the balance gets disrupted when DHT is reduced. Have Nolva on hand. It's also not advised to use with Deca, have to look up the exact scientific reason for you.

 

[jlh98765]

I guess the main conflicts I have seen is depending on what you're taking, like deca, and whether finasteride is worth taking. I am on npp, which technically isn't deca. But would you consider npp having the same reactions as deca even though it has a shorter half life?

I will probably run the finasteride for prostate reasons. What is recommended dosage and frequency?

 

[Joe Stick]

since you have proscar just split it into 4ths and take one 4th everyday. running finasteride and deca at the same time can make you shed hair. how much are u running anyway? if test is going to be your base compound then i would definitly run finasteride.

 

[jlh98765]

I'm running 75mgs test prop & 50mgs npp ED.

 

[krishna]

It would be better to run the proscar to protect your prostrate during your cycle. The conflicting info about deca and finasteride is that when you mix the two it can accelerate hairloss because deca doesnt get reduced to a weaker androgen by the 5 AR enzyme, but if your main concern is your prostrate then it would be better to use proscar to keep DHT levels to a minimum.

Im assuming that deca doesnt have as much effect on the prostrate as DHT would. K UP!!!

The same mechanisms that cause hair loss are the ones that also cause prostate swelling. I'd say running proscar and deca will have the same negative effect that it does with hair loss. I'd go with Saw Palmetto Extract in this situation if I were you.

 

[jlh98765]

Is Saw Palmetto legitimately effective for prostate problems? Anyone else have first hand experience?

 

[krishna]

Yes, and there have been some clinical trials that show the results are practically as good as finasteride.

 

[Ulter]

Nandrolone does not accelerate hairloss while using Proscar.
DHT is a weaker factor of prostate problems than Estrogen. It takes both and E is much more to blame. Saw Palmetto may be enough for prostate issues alone.

 

[eliteforce]

I did that once to save money, but it didn't work as good as when I was using 1mg propecia, I think those sobs put all the fini on 1 side of the proscar tablet so we have to pay more

I split a (5mg) proscar tablet in 4 and take a piece (1.25mg) a day
.

 

[krishna]

Nandrolone does not accelerate hairloss while using Proscar.
DHT is a weaker factor of prostate problems than Estrogen. It takes both and E is much more to blame. Saw Palmetto may be enough for prostate issues alone.

Sure it can bro......I've got piles of research that say otherwise. And as far as estrogen, they actually use it to treat certain prostate conditions including prostate cancer, but I admit that it can also lead to swelling and other conditions.

 

[Joe Stick]

Nandrolone does not accelerate hairloss while using Proscar.
DHT is a weaker factor of prostate problems than Estrogen. It takes both and E is much more to blame. Saw Palmetto may be enough for prostate issues alone.

Really? So your saying that deca and finasteride can be used at the same time without causing major shedding? Couldve sworn i read in several posts the opposite though. if u are right then that is sweet because i didnt want to try deca because im on finasteride year round. any1 else kno?

 

[krishna]

Really? So your saying that deca and finasteride can be used at the same time without causing major shedding? Couldve sworn i read in several posts the opposite though. if u are right then that is sweet because i didnt want to try deca because im on finasteride year round. any1 else kno?

This is the reason it CAN cause shedding is thus: Deca is a potent androgen on the receptors until it is reduced to dihydronandrolone (dhn) via the 5ar enzyme. This is the same enzyme that converts test to dht, which causes hair loss. So you see, proscar has the opposite effect with nandrolone because by not allowing it to convert to the less potent dhn, it stays in a more potent form, which creates potential for more shedding.

 

[Ulter]

OK let me clarify that a little because I said it wrong. If you're prone to hairloss and you want to use test in a cycle then you should use finasteride whether you use deca or not. Finasteride has no affect on tren. Nice catch, thanks.
Same applies to prostate.

 

[Ulter]

No, some studies show that DHN is actually more androgenic than it's parent. This is Nandi's post on it stating he thinks it's weaker. Most people using test with finasteride do not see an increase in hair loss when they add nandrolone.

people often make the mistake of equating high androgen receptor (AR) binding affinity with androgenicity, probably because DHT possesses both properties. There is a notion, likely started by this paper (1) that the 5 alpha reduced version of nandrolone is a weaker androgen than the parent compound. The opposite is true with testosterone. Hence the often read admonition not to combine finasteride with Deca, because it would be bad for the hair and prostate. To quote from (1),

"In the accessory sex organs (e.g. the prostate) testosterone is 5 alpha-reduced to dihydrotestosterone (DHT) which, due to its higher affinity for androgen receptors (AR), amplifies the action of testosterone. In contrast, when 19-nortestosterone (NT) is 5 alpha-reduced, its affinity for AR decreases, resulting in a decrease in its androgenic potency."

In other In vivo studies the picture is different (2). Quoting from this paper,

"The results of AR binding studies revealed that 5alpha-reduction of T and ET significantly enhanced their affinities, and that the 5alpha-derivative of 19norT displayed a similar binding affinity to that exhibited by 19norT. In terms of biological activity, the results showed that 5alpha-reduction of T and 19norT significantly increased their androgenic potency..."

Here androgenic potency was determined in part by action on the prostate. So these two papers are completely at odds with one another, and I wouldn't assume that the commonly held belief that 5 alpha reduced nandrolone is a weaker androgen than the parent compound is necessarily true.

If you are worried about your prostate, avoid agents that are subject to 5 alpha reduction, and that have a low anabolic/androgenic ratio.


(1) J Steroid Biochem Mol Biol. 1995 Jun;53(1-6):253-7.
Different patterns of metabolism determine the relative anabolic activity of 19-norandrogens.
Sundaram K, Kumar N, Monder C, Bardin CW.

(2) J Steroid Biochem Mol Biol. 1997 Jan;60(1-2):121-9.
5alpha-reduction of norethisterone enhances its binding affinity for androgen receptors but diminishes its androgenic potency.
Lemus AE, Enriquez J, Garcia GA, Grillasca I, Perez-Palacios G

 

[krishna]

All I know is that everything I've read says that dhn is weaker than its parent.

 

[Ulter]

Well there's a study that says it's not. The bottom line is that until a study is actually done on humans using nandrolone and finasteride the debate will rage on. Don't hold your breath.
Like I said, when these issues are argued on paper and both side have clinical evidence backing what they say I defer to the man on the street. Which is where the truth lies in the first place. Most people have no accelerated hairloss from adding deca to test with Proscar.

 

[Joe Stick]

damn at all the conflicting info looks like ill just have to volunteer to be a guinneau pig

 

[bilter]

keep us posted on your findings

 

[krishna]

Well there's a study that says it's not. The bottom line is that until a study is actually done on humans using nandrolone and finasteride the debate will rage on. Don't hold your breath.
Like I said, when these issues are argued on paper and both side have clinical evidence backing what they say I defer to the man on the street. Which is where the truth lies in the first place. Most people have no accelerated hairloss from adding deca to test with Proscar.

Ya that's odd that one study would show it does, and another study have the opposite results. We should open a poll thread and see how it has affected the members on here. I know I've heard some say using deca and finasteride killed their hair.

 

[OMEGA]

What conflicting info have you heard?

I split a (5mg) proscar tablet in 4 and take a piece (1.25mg) a day on my 500mg/week test cycle (with 40mg-4week-tbol kick start) to reduce the extra amount of DHT that occurs while on cycle. Beter safe then sorry is what I think.

Only thing you have to look for when taking finasteride, is that it can affect some people's libido (not likely on a test cycle), the chance of gyno increases as DHT is an anti-estrogen so the balance gets disrupted when DHT is reduced. Have Nolva on hand.

good thoughts