I made Primo at 2/20 at 200mg and that was absolutely painfree, I even did quad shots with it and I couldnt even tell I had done the shot the next day..
I have made at 250mg and I mucked up the calcs and used 5% ba and 20% bb, now that bloody hurts.. I think if I had used 2/20 that would have been painfree also..