Please Scroll Down to See Forums Below
napsgear
genezapharmateuticals
domestic-supply
puritysourcelabs
UGL OZ
UGFREAK
napsgeargenezapharmateuticals domestic-supplypuritysourcelabsUGL OZUGFREAK

pls. post NEUROGENEX feedback HERE

macrophage69alpha said:
probably more effective to add a small amount of hydergine(very small) and selegiline (1mg ed or eod)
Click to expand...

Macro, I'm curious about the above statement. I have found that Hydergine works very synergistically not only with Piracetam (several studies account for the effect), but with NRGNX overall. What is the amount that you recommend, ie. what do you mean by 'very small'? I take 2 tabs which constitutes 9mg of Hydergine. BTW I have never seen anything accounting for toxicity of hydergine before...what gives?

And as far Selegiline being better than Cabergoline, I disagree, at least for me Caber blows away l-Dep, but then everyone responds differently. Have never tried Bromo though..
 
juve said:


Macro, I'm curious about the above statement. I have found that Hydergine works very synergistically not only with Piracetam (several studies account for the effect), but with NRGNX overall. What is the amount that you recommend, ie. what do you mean by 'very small'? I take 2 tabs which constitutes 9mg of Hydergine. BTW I have never seen anything accounting for toxicity of hydergine before...what gives?

And as far Selegiline being better than Cabergoline, I disagree, at least for me Caber blows away l-Dep, but then everyone responds differently. Have never tried Bromo though..
Click to expand...

from a health and "natural" mental state- selegiline is better. Caber is of course much stronger.

hydergine amplifies the effect too much in some people hence why the reccomended low dose- some people enjoy the higher dose that you use- it really varies- however best advice is to start low and work up- its rarely better the other way.
 
Im a bit confused macro... to reach the full effects of hydergine people stay on it for at least a month... how can it be used sparingly.


Why should I skip hydergine if ive got tabs instead of liquid.


A warning... arcalion with piracetam and DMAE is a bit too much, bad combination IMO. Counterproductive for me at least.
 
About Hydergine and the effects on dopamine... was on the other thread.

Despite the fact that hydergine has been used in the treatment of dementia for many years, its mechanism of action is still not clear. Current studies imply that the major effect of hydergine may be the modulation of synaptic neurotransmission rather than solely increasing blood flow as was once thought. A prominent feature that accompanies aging is an increase in monoamine oxidase (MAO) levels which results in decreased availability of catecholamines in the synaptic cleft. The aim of this study was to determine the effects of hydergine on the MAO activity in different brain regions (cortex, olfactory bulb, hypothalamus, hippocampus, striatum, cerebellum) of old (30 months) and adult (12 months) male Sprague-Dawley rats. In cortex and olfactory bulb MAO levels were higher in the aged group. In hippocampus and hypothalamus hydergine treatment caused significant decreases in MAO levels. An interaction between age and hydergine treatment was observed in the hypothalamus, hippocampus and cerebellum. The hydergine effect was more pronounced in the aged group in the hypothalamus and cerebellum, and more pronounced in the adult in the hippocampus. Our findings imply that increased brain MAO activity in aging can be modified by hydergine treatment in some brain regions.
 
The effect of Co-dergocrine (Hydergine) on acetylcholine (ACh) release in the striatum and hippocampus has been studied by means of brain microdialysis and compared to the effect of SKF 38393 and of LY 171555 selective D1 and D2 dopamine (DA) receptor agonists, respectively. Co-dergocrine (1 and 5 mg kg-1 i.p.) as well as LY 171555 (0.2 and 0.5 mg kg-1 i.p.) decreased the extracellular concentration of ACh in the striatum, whereas SKF 38393 (5 and 10 mg kg-1 i.p.) increased it. On the other hand, Co-dergocrine (1 and 5 mg kg-1), LY 171555 (0.2 and 0.5 mg kg-1) and SKF 38393 (5 and 10 mg kg-1) increased ACh release in the hippocampus in a dose-dependent way. These results show that Co-dergocrine, which is widely used in the treatment of senile mental decline, enhances the release of ACh in the hippocampus in a similar manner to both D1 and D2 DA agonists. This effect might be relevant for the amelioration of cognitive processes. Moreover, our results which demonstrate that Co-dergocrine is able to decrease the release of ACh in the striatum, as are selective D2 agonists, suggest that Co-dergocrine may have a potential therapeutic benefit in Parkinsonian dementia.
 
the issue was that in combination with neurogenex some people may find it to be too strong, hence the indication to start low and see how hydergine affects YOU (ie the individual).

JMHO
 
Caution would be advised it seems.

One of the first things you read about when you read about SD's is the synergy between pira and hydergine. But from what I've read on boards people have difficulties getting it right, and some people will never get it right.

Paradoxical effects are an issue, but then again there are people who take large amount and dont feel totally stupid.


This was james south smart drug regime, dont know how he dose it though


My current nootropic intake includes:
Piracetam (2.4 grams, 2-4 times daily)
Pramiracetam (300mg twice daily)
Aniracetam (375 mg twice daily)
Oxiracetam (400 mg twice daily).
I also use:
Pyritinol (100-200 mg daily)
Hydergine (4.5-6.75 mg daily)
Vinpocetine (2.5-7.5 mg daily)
on occasion, especially when writing.
 
what are the effects of selegiline? and would it be beneficial to combine that with neurogenex? and where can you get it?

thanks.
 
Might as well post my comments here. I've been on neurogenex for one week now. I've also bought 300 grams of piracetam from BAC and have been loading with that. To tell you the truth, I really can't notice any difference as of yet. I've been taking 6 pills for the first 3 days and 2 pills thereafter. As for the piracetam powder, i've been taking 5 grams a day (everything in the morning on an empty stomach.) I'll update if I notice a difference in cognitive abilities, but then again I really don't know what to look for in terms of positive effects.
Will update again in another week.
 
got a 100

been on neurogenex for bout 3 months, and got a 100 on my heat transfer exam, highest in the class.....hell yeah!!!!

about 7 days out before the exam, i increased my dosage to 6caps/day. and it worked out really well. im back down to 3caps/day. but will increase again during finals.
might pick up seligiline after finals is over.
 
macrophage69alpha said:
with that much piracetam you may need to increase choline intake (piracetam uses up choline)
Click to expand...

picking up some ALPHA GPC as we speak. To tell you the truth, yesterday I noticed a type of wired, focused feeling throughout the day even though I hadn't slept for 30 hours. I took 3 pills in the am and pm and could not go to sleep for the life of me. I was on the internet just reading articles on stuff I would never ever want to read. Four hours stuck to the screen, just reading. Could it be possible that the lack of sleep amplified the nootropics effects? I definately felt my mind racing when i took that dose throughout the day.
 
traxZBT,

the alphagpc should help, but think that you may be taking the piracetam too high.

and yes the nootropic effects can be very noticable with sleep deprivation
 
has anyone ever had an anxiety attack on this stuff? i get anxiety once and a while and it feels as if im unbalanced somewhere in my brain. however im not depressed so this stuff might give me that extra edge im looking for
 
I just started my doses today at 3/day. I have to take my MCAT in april so we'll see how much I improve from my last MCAT score (scored 90th percentile but I'm taking it again because I need to get >95th percentile for the med schools i'm aiming for). I also started taking t-rex at 4/day. i'll keep you guys updated on my progress.
 
blz said:
I just started my doses today at 3/day. I have to take my MCAT in april so we'll see how much I improve from my last MCAT score (scored 90th percentile but I'm taking it again because I need to get >95th percentile for the med schools i'm aiming for). I also started taking t-rex at 4/day. i'll keep you guys updated on my progress.
Click to expand...

updates always appreciated
 
Hrmm well here's an update. I'm taking neurogenex (3/day) and thermorexin(4/day) and so far i can't really say much and I dont really notice anything different in terms of concentration, visual acuity, and general cognitive functioning. Starting tomorrow I begin studying for my upcoming exam so we'll see how I'm progressing. I was just wondering if there are any additional supplements (vitamins, etc.) i should take to allow neurogenex to work more optimally. Thanks
 
I just bought two bottles of this stuff and was wondering if it is ok to take with my other supplements. i am currently takeing

No2
r-ala
xenadrine efx
multivitamin
fish oil caps
glutamine
zma

any info would be appreaciated..
 
If your fairly young (ie 19, 20) can this HURT cognitive performance? For some reason after I take a few caps I have a harder time thinking clearly it seems (then again...Discrete math at 8 in the morning may have a large part in that as well)
 
its theoretically possible that there can be too large an increase in neurotransmitter levels in subjects with already high levels, cut your dosage in the am to see if effect still occurs.
 
MACRO,
okay im gonna pick up more neurogenex this week with alcar and ALTYR and choline.
i have two questions how do much altyr do you take for nootropic effects? and where can i pick up choline?
thanks.
 
EricDraven said:
MACRO,
okay im gonna pick up more neurogenex this week with alcar and ALTYR and choline.
i have two questions how do much altyr do you take for nootropic effects? and where can i pick up choline?
thanks.
Click to expand...


500mg-1g 2-3 times a day. though many people use higher doses, really depends on individual responses.

Choline is widely available.
bitartrate is the cheapest.
CDP and GPC are the two most bioavailable (also the most expensive)
 
macrophage69alpha said:
^
Click to expand...

Got mine on Friday, doing three a day (won't load, but might do 5 a day for three days next week during first round of tests). Using 40 mg vonpocetine a day with it. Will try to pick up choline bitartrate later today or tomorrow (is it sold at GNC or Vitamine Shoppe?), will do 1g twice a day. Alcar and Altyr will come in a few weeks (stretching the pennies for now). Anything else that I should stack it with?
 
You could add some more DMAE if you wanted. Although it's cheap, you are probably going to be hitting the law of diminishing returns by this point.
 
ohashi said:


Got mine on Friday, doing three a day (won't load, but might do 5 a day for three days next week during first round of tests). Using 40 mg vonpocetine a day with it. Will try to pick up choline bitartrate later today or tomorrow (is it sold at GNC or Vitamine Shoppe?), will do 1g twice a day. Alcar and Altyr will come in a few weeks (stretching the pennies for now). Anything else that I should stack it with?
Click to expand...

choline is good, and yes its sold at most any vitamin store.

many people also stack selegiline (available from europe)
 
ohashi said:


Got mine on Friday, doing three a day (won't load, but might do 5 a day for three days next week during first round of tests). Using 40 mg vonpocetine a day with it. Will try to pick up choline bitartrate later today or tomorrow (is it sold at GNC or Vitamine Shoppe?), will do 1g twice a day. Alcar and Altyr will come in a few weeks (stretching the pennies for now). Anything else that I should stack it with?
Click to expand...

Instead of Choline Bitartrate look into purchasing Alpha-GPC and DL-Phenylalanine.
An advanced stack could also include Hydergine (4.5-9mg's ED), Deprenyl (5 mg's ED/EOD or liquid deprenyl - selepryl at 1-2mg ED/EOD), SAM-e and Betain tri-methyl-glycine.
You could always add more piracetam, since it's cheap as dirt now - 3g's ED is good.
 
okay, i have my neurogenix, and am thinking about adding some to it. So in order of preference (I'm sure I can't take as much as fonz) what should I add? and what dose? I'm thinking alcar and dmae right now (?).
 
Just my update. I haven't been taking it for long, but I seem to be much more on task already! I'm one of those people who can have a term paper due, get online to do research, and end up reading posts at elite. I have had a MUCH easier time stay on track. Still waiting on full effects though, supposedly takes a month. More from me then!
 
I took 2 caps.

I was then able to completely understand quantum mechanics.

I went off and now I am back on page 6 of my new coloring book!
 
i have an interesting question here. with all of these extra neurotransmitters from the nootropics (ie. acetylcholine), how is one's sex drive or function effected (ie. erection strength, arousal, etc.) just curious.
 
another question. the fact that this product alters different neurotransmitters is slightly scary to me (especially dopamine). can you explain if and how this product upregulates these neurotransmitter receptors? also, what prevents the body from adjusting to all these changes by downregulating receptors to form a homeostasis? i just do not understand enough about this yet, so any clarification is greatly appreciated. thanks.
 
I'm on bottle number 2 now (I have a 3rd waiting for when this one is done). So far I am pleased, I have one final left and grades should be out next week, so THAT is the big concern and I will post again when those are up!!
 
another question. you guys aren't keeping up with me, lol. anyway, how is this product different from an amphetamine like adderall. i ask this b/c i used to be hooked on adderall xr 30mg/day (prescribed for my a.d.d.) and went through hell when i finally stopped taking it. i know there are many major differences between the two, but i also know that adderall, like this product, cause changes in neurotransmitters especially dopamine. and the adderall left me with some severe social phobias, body dysmorphic disorder, anxiety probs, and the list goes on. also, i am not so sure that i wasn't left with some long term damage to my autonomic nervous system. thanks.
 
I don't think there is much comparison between the two products. You have a mild OTC supplement and an amphetamine. I would say a similar reaction from neurogenex is unlikely, but perhaps someone whos used both can give some feedback.
 
anyone know if this is ok to take w/welbutrin? im on 350mg welbutrin a day for lack of attention and i've been wanting to try this stuff.
 
flexshack said:
another question. you guys aren't keeping up with me, lol. anyway, how is this product different from an amphetamine like adderall. i ask this b/c i used to be hooked on adderall xr 30mg/day (prescribed for my a.d.d.) and went through hell when i finally stopped taking it. i know there are many major differences between the two, but i also know that adderall, like this product, cause changes in neurotransmitters especially dopamine. and the adderall left me with some severe social phobias, body dysmorphic disorder, anxiety probs, and the list goes on. also, i am not so sure that i wasn't left with some long term damage to my autonomic nervous system. thanks.
Click to expand...

neurogenex will go, a least part of the way, to undoing the damage done by amphetamine (adderall) use.
 
flexshack said:
i have an interesting question here. with all of these extra neurotransmitters from the nootropics (ie. acetylcholine), how is one's sex drive or function effected (ie. erection strength, arousal, etc.) just curious.
Click to expand...


most report improved or unnaffected(though amount will vary among individuals and aspect). no reports of negative impacts on any of those aspects.
 
macrophage69alpha said:
neurogenex will go, a least part of the way, to undoing the damage done by amphetamine (adderall) use.
Click to expand...

but how is this product different from adderall when talking about their effects on neurotransmitters?
 
flexshack said:
but how is this product different from adderall when talking about their effects on neurotransmitters?
Click to expand...

mechanistically it is wholely different. in the most basic sense adderal works by "jacking up" your CNS. Neurogenex works by restoring, enhancing and upregulating your neurotransmitter production, release, life and receptor activity.

if you would like a more specific/technical answer, one can be made available. though it will take some time
 
Question for Macro. I have my fiancee on 2 caps a day and she's reporting nausea. Is this a potassium deficiency issue as kown with the t-rex? what else can be done to help her out?
 
macrophage69alpha said:
mechanistically it is wholely different. in the most basic sense adderal works by "jacking up" your CNS. Neurogenex works by restoring, enhancing and upregulating your neurotransmitter production, release, life and receptor activity.

if you would like a more specific/technical answer, one can be made available. though it will take some time
Click to expand...

it would be really great and much appreciated if you could give me a more specific/technical answer. thank you in advance.
 
I said I'd post after exams. So here I am! Well, my GPA went up .3 this quarter, which helped! Can't say whether supplementing helped or not, but for me the higher the better!
 
Hey bro's can some start a thread to give me some advice on my first cycle? I already spent a fortune on 2 bottles of QV Anavar and am thinking of adding EQ. I am battling a fairly bad case of Tennis Elbow (I think). Please help me do this right. TIA
 
bdog527 said:
Macro,

Do you think St. John's Wort, via upregulation of CYP3A4 hepatic enzymes, negate Neurogenex?
Click to expand...

may increase metabolism of Galantamine
otherwise should not have impact.

however their may be interactions, the mechanism(s) of st johns are not entirely clear... even which constituents have activity is still in dispute.
 
Never felt a difference with the stuff and I took 4caps/day for 4 months. But then again, I had no true way of assessing whether or not it was working.
 
Been taking Neuro for several months now and what can I say? The stuff kicks ass, for me personally it works better and better the longer I take it. I take 3 caps twice daily, that dose is on the high end but I notice a definite difference.

Good shit!


Also Macro my girlfriend is taking wellbutrin xl right now and wants to start taking neurogenex. Would it be ok to combine the two together? I went ahead and ordered some for her because I really don't see an interaction but I wanted to be on the safe side.
 
there should be no issue. There is the potential for high dopamine and acetylcholine levels, (as a note- many find this a desirable "side effect") though at normal dosing this should not be an issue.
 
glad to find my way back to this site. I have been away for a few years and am glad to see some of the old vets still here. Macr,fonj,frackal,ulter and a few of the others,.
 
macrophage69alpha said:
there should be no issue. There is the potential for high dopamine and acetylcholine levels, (as a note- many find this a desirable "side effect") though at normal dosing this should not be an issue.
Click to expand...


Thanks macro, she started taking it today so far "ok".
 
You must log in or register to reply here.

Similar threads

Liquid Gold Labs
💎 Liquid Gold Labs Feedback + Reviews 💎
Replies
26
Views
4K
brenno
B
C
Bad experience / vendor feedback
Replies
12
Views
1K
the_alcatraz
the_alcatraz
JimAbs43
Podcast Evolutionary.org Hardcore 2.0 #91 - 15ml Vials the feedback is in - Euro Pharma
Replies
8
Views
614
wootoom
wootoom
B
Feedback on long-term bodybuilding plan
Replies
3
Views
293
the_alcatraz
the_alcatraz
P
Legitimacy of PSL
Replies
8
Views
681
RoySimpson
RoySimpson
Top Bottom