Two different hormones. Both affect the same thing through different paths. P Seven will not make you "foggy" but it's not as fast acting. It can't be since it's not inhaled. Too much P Seven can make you unmotivated while making you mellow, so don't lather it on thinking, "oh it's just a supp". You'll end up on the couch all day watching TV and wondering if the Pizza guy will bring your food all the way to the couch for you so you don't have to get up.