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Nolvadex alone to increase test.

jonbmd

New member
I've just started looking into gear and have done alot of reading. There are several case reports on medline about using Tamoxifen to increase natural testosterone production in highly trained endurance athletes with hypogonadotropic hypogonadism. Has anyone tried this and do you think it is safe?
 
Key term: "hypogonadotropic hypogonadism" -if you are hypogonadal, then yes it would probably help. If your balls are in full working order, then no it won't do a damn thing.
 
B182 said:
Key term: "hypogonadotropic hypogonadism" -if you are hypogonadal, then yes it would probably help. If your balls are in full working order, then no it won't do a damn thing.

I think this is correct.
 
Treatment of idiopathic oligozoospermia with tamoxifen.

Brigante C, Motta G, Fusi F, Coletta MP, Busacca M.

Eighteen subfertile men, with idiopathic normogonadotropic oligozoospermia were treated with an antiestrogenic compound, tamoxifen (Nolvadex), at the dose of 20 mg/day for four months. Hormonal parameters (LH, FSH, Testosterone, Prolactin) were evaluated before treatment and after 45 and 90 days of therapy. Serum LH, FSH and Testosterone increased significantly after 45 days of tamoxifen treatment. Seminal analyses, performed before and after three months of therapy showed improvements in sperm motility and in sperm density. By our clinical findings, tamoxifen can be considered a useful approach for an empiric treatment of idiopathic oligozoospermia.


(According to this article, these men had normal levels of gonadotropins but their testosterone still increased on tamoxifen.)
 
Int J Androl. 1992 Dec;15(6):507-8

Treatment of idiopathic oligozoospermia with tamoxifen--a randomized controlled study.

Krause W, Holland-Moritz H, Schramm P.

Department of Andrology, Philipps-Universitat, Marburg, Germany.

There is no conclusive evidence of the usefulness of tamoxifen in the treatment of idiopathic oligozoospermia (OAT-syndrome), as it has been used mostly in uncontrolled studies. We herein report on the controlled treatment of OAT-syndrome with tamoxifen versus placebo following a randomized design. Seventy-six men with sperm counts of 2-20 x 10(6) ml-1, sperm motility of 20-50%, and sperm morphology (abnormal cells) between 50 and 80% were involved in the study. Patients with varicocele, a history of testicular maldescent or genital inflammation were excluded. Thirty-nine patients received tamoxifen (30 mg daily), 37 patients placebo. There was a statistically significant increase in the mean serum testosterone level after treatment in the tamoxifen-treated group (from 4.9 +/- 1.9 to 7.9 +/- 3.6 ng ml-1) in comparison to the placebo group (5.3 +/- 2.0 and 5.6 +/- 2.0 ng ml-1). Serum FSH levels increased slightly in the tamoxifen group (from 6.8 +/- 4.1 to 7.3 +/- 4.8 mU ml-1), but this was not statistically significant in comparison to the placebo group (from 5.9 +/- 3.9 to 5.2 +/- 3.5 mU ml-1). Serum levels of LH did not show any differences between groups. The sperm count increased during treatment from 9.3 +/- 11.7 to 11.4 +/- 13.7 x 10(6) ml-1 in the tamoxifen group and from 9.1 +/- 7.1 to 9.3 +/- 8.8 x 10(6) ml-1 in the placebo group; this difference did not reach statistical significance. The percentage of motile and abnormal sperm was not different between the two treatment groups

(these were also normogonadotropic men whose test. increased from 4.9 to 7.9 on tamoxifen)
 
I've read several articles about strenuouse exercise causing suppresion of the HPTA, I was wondering if this is what is really happening when you over train?
 
Yes it does....My endo just wrote me a script for it... clomid messes with my eyes to much ...I start the tomaxafin in July ( when I come off andro gell) with regular blood work. The script says 3x a day eod. I will probably throw in some clomid M,W,F to speed up the recovary...........
 
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