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No More HDL Problems!!!!! new treatment on horizon.

geoboy

New member
mmmmmmm. pizza, greasy cheeseburgers, fried sugar cubes with Bosco and ice cream, with a side order of Var, winny and tren.

if anyone has the full JAMA article, plz post. This is GREAT news.
Experimental treatment works like `liquid Drano' for coronary arteries.

according to other stories, it arose from the study of a group of people in city/town of Limone in Italy who ate like cavone's and didnt excercize and no one died of heart disease. turns out they had a mutant gene that caused them to produce a super-HDL. scientists then engineered a synthetic analogue. works like magic.

it's still experimental, but this is the future of (no) heart disease.


here is story:
------------------------
Following is advance for use after 4 p.m. EST. (Chicago-AP) -- A small study indicates a new drug can do for coronary arteries what drain cleaner does for drains.

The intravenous drug is a synthetic component of H-D-L -- the "good" cholesterol. H-D-L removes fatty buildups called plaque from the bloodstream.

In the study, 36 patients who had heart attacks or severe chest pain got weekly infusions for five weeks. At six weeks, they averaged a four percent reduction in plaque in their coronary arteries.

One researcher calls the drug "sort of liquid Drano for the coronary arteries." Another researcher says the study shows the concept is right. But he says larger and longer studies will be needed to check the drug's potential as a treatment.

The researchers are at the Cleveland Clinic.

The study is in the Journal of the American Medical Association.

(Above is advance for use after 4 p.m. EST.)
 
these are nice news!!...my dad has 5 bypasses after 2 surgerys...and i'm genetically the same..so i will finish the same...
 
Very cool, which peer review is it in? I have access to everything at the university libaray.
 
Um yeah this sounds great, but read more closely - it only made a 4% difference over those receiving a placebo. If your arteries are say 40% blocked, and you take the drug, it works like magic and afterwards, your arteries are still over 38% clogged. So dont go crazy just yet
 
JuicePimp said:
Um yeah this sounds great, but read more closely - it only made a 4% difference over those receiving a placebo. If your arteries are say 40% blocked, and you take the drug, it works like magic and afterwards, your arteries are still over 38% clogged. So dont go crazy just yet

JuicePimp:
but it was a 4% improvement over course of literally a few weeks (5). same dose continued or larger dose and poof. clean(er) arteries. Stop giving aid and comfort to cholesterol (j/k).

Bodybyfinaplix:
its the Journal of the American Medical Association.
 
geoboy said:


... same dose continued or larger dose and poof. clean(er) arteries. Stop giving aid and comfort to cholesterol (j/k).

Bodybyfinaplix:
its the Journal of the American Medical Association.

Oh yeah, I forgot we all like to take more than the recommended dose. :D
 
Good news, I wonder if they can make it economically viable and inexpensive enough for use in the general public.
 
pharmguy said:
I have always wondered why they don't have a synthetic exogenous HDL

Because just imagine if nobody dies from heart problems in America...our population goes to the roof, more 3rd age to keep living, add to this the undiscriminated immigration that bring here millions of people every year...our governemnt knows that. And we have the technology so far.

American government and all the intelligence agencys know very well that the main cause for all the actual global problems is over population. And it will be worst. The only hope is a global big war (the 3rd one) that end with the lives of one third of the world population. In that way we could start again literally from Zero.
 
good points, I quess it's the same way with cancer, the money they spent on the war was enough to find a cure for cancer.

But then again how hard is it to make synthetic exogenous HDL??
 
Here is a link an a portion from a article that I found that mentions how much higher life expectancy would increase if heart disease was eliminated.

http://www.sciencedaily.com/releases/2000/01/000104065154.htm

An exerpt:

DALLAS, Dec. 30 -- If all major forms of heart and blood vessel disease were eliminated, U.S. life expectancy would rise by almost seven years and the nation would be more than $300 billion richer, according to the American Heart Association's 2000 Heart and Stroke Statistical Update, an annual report released today.
The report updates statistics on death and prevalence rates for cardiovascular disease and stroke.

"We've seen remarkable progress in fighting heart disease and stroke during the last half century, but cardiovascular disease is still the No. 1 cause of death for both men and women," says American Heart Association President Lynn Smaha, M.D., Ph.D.

Nearly 60 million Americans have some form of heart or blood vessel disease, which claimed 953,110 lives in 1997, the most recent year for which data are available, the report says. Cardiovascular disease accounted for about 41 percent of all deaths, or one out of every 2.4 deaths, and was listed as the primary or a contributing cause of death on more than 1.4 million death certificates that year"...

"
 
djufo said:


Because just imagine if nobody dies from heart problems in America...our population goes to the roof, more 3rd age to keep living, add to this the undiscriminated immigration that bring here millions of people every year...our governemnt knows that. And we have the technology so far.

American government and all the intelligence agencys know very well that the main cause for all the actual global problems is over population. And it will be worst. The only hope is a global big war (the 3rd one) that end with the lives of one third of the world population. In that way we could start again literally from Zero.

I don't know if I agree with the second part of your post, but I agree with the first part. and add to that all the cardiologists, all the angioplasties hospital stays zocors mevacors lovistatin etc etc etc. that will no longer be needed. BILLIONS & BILLIONS of dollars evaporates.

This might turn out like the urban legend of the oil companies buying the technology for water-powered engines and then spiking it.
 
geoboy said:


I don't know if I agree with the second part of your post, but I agree with the first part. and add to that all the cardiologists, all the angioplasties hospital stays zocors mevacors lovistatin etc etc etc. that will no longer be needed. BILLIONS & BILLIONS of dollars evaporates.

This might turn out like the urban legend of the oil companies buying the technology for water-powered engines and then spiking it.


Whats a cardiologist to do?? LOL!!!
No theyll be plenty of arrythmias, heart failure patients, leaky or stenotic valves etc.... I mean the heart has to go sometime so if its not the arteries then its the muscle and structure so it may just delay the medical bills or actually increase them. Heart failure is more expensive that cancer to treat each year. ANd not to mention the small plaques that remain that can rupture and cause a heart attack and emergency angioplasty and then add to that all of the joe sixpacks out there who wont take their medicine. No ones worried about their job quite yet:mexican:
 
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