First off, the primary health risk of using MDMA is liver damage. It is very stressful on the liver, and for that reason it should be avoided while cycling, especially if you are using any 17-aa steroids. Now take this bit of advice for what its worth, folks. I gave myself hepatitis from rolling and shooting winstrol at the same time. I know what I'm talking about when I say you should avoid it when cycling. Unless, of course, you like the yellow look.