New Evidence Against HMB

[rjl296]

feels like deca

 

[Deak]

I think you could get some results with HMB or other amino acids supplements, only if you would take 20-30g a day....

 

[u4ik_RAGE]

Charles Poliquin says he found 9 grams to be benificial to his recovery when I emailed him. My good buddy on this board, Cytomel, will back me up.

 

[babbabuee]

sure, you found a report that says it's bunk, and I read a report that said it works. all these supplements are like that.

 

[Singleton]

Maybe it does work

http://www.ncbi.nlm.nih.gov/entrez/...ve&db=PubMed&list_uids=10978853&dopt=Abstract

Nutritional supplementation of the leucine metabolite beta-hydroxy-beta-methylbutyrate (hmb) during resistance training.

Panton LB, Rathmacher JA, Baier S, Nissen S.

Department of Education, East Tennessee State University, Johnson City, Tennessee 37614, USA. [email protected]

The effects of supplementation of the leucine metabolite beta-hydroxy-beta-methylbutyrate (HMB) were examined in a resistance training study. Thirty-nine men and 36 women between the ages of 20-40 y were randomized to either a placebo (P) supplemented or HMB supplemented (3.0 g HMB/d) group in two gender cohorts. All subjects trained three times per week for 4 wk. In the HMB group, plasma creatine phosphokinase levels tended to be suppressed compared to the placebo group following the 4 wk of resistance training (HMB:174. 4 +/- 26.8 to 173.5 +/- 17.0 U/L; P:155.0 +/- 20.8 to 195.2 +/- 23.5 U/L). There were no significant differences in strength gains based on prior training status or gender with HMB supplementation. The HMB group had a greater increase in upper body strength than the placebo group (HMB:7.5 +/- 0.6 kg; P:5.2 +/- 0.6 kg; P = 0.008). The HMB groups increased fat-free weight by 1.4 +/- 0.2 kg and decreased percent fat by 1.1% +/- 0.2% while the placebo groups increased fat-free weight by 0.9 +/- 0.2 kg and decreased percent fat by 0.5% +/- 0.2% (fat-free weight P = 0.08, percent fat P = 0.08, HMB compared to placebo). In summary, this is the first short-term study to investigate the roles of gender and training status on the effects of HMB supplementation on strength and body composition. This study showed, regardless of gender or training status, HMB may increase upper body strength and minimize muscle damage when combined with an exercise program.

Publication Types:

* Clinical Trial
* Randomized Controlled Trial


PMID: 10978853 [PubMed - indexed for MEDLINE]

Another one:
http://www.ncbi.nlm.nih.gov/entrez/...ve&db=PubMed&list_uids=11128859&dopt=Abstract

Beta-hydroxy-beta-methylbutyrate ingestion, Part I: effects on strength and fat free mass.

Gallagher PM, Carrithers JA, Godard MP, Schulze KE, Trappe SW.

Human Performance Laboratory, Ball State University, Muncie, IN 47306, USA.

PURPOSE: The purpose of this investigation was 1) to determine whether HMB supplementation results in an increase in strength and FFM during 8 wk of resistance training and 2) determine whether a higher dose of HMB provides additional benefits. METHODS: Thirty-seven, untrained, college-aged men were assigned to one of three groups: 0, 38, or 76 mg x kg(-1) x d(-1) of HMB (approximately equal to 3 and 6 g x d(-1), respectively). Resistance training consisted of 10 different exercises performed 3 d x wk(-1) for 8 wk at 80% of 1-repetition maximum (1RM). The 1RM was reevaluated every 2 wk with workloads adjusted accordingly. RESULTS: No differences were observed in 1RM strength among the groups at any time. However, the 38 mg x kg (-1) x d(-1) group showed a greater increase in peak isometric torque than the 0 or 76 mg.kg(-1) x d(-1) groups (P < 0.05). The 76 mg x kg(-1) x d(-1) group had a greater increase in peak isokinetic torque than the 0 or 38 mg x kg(-1) x d(-1) groups at 2.1, -3.15, and -4.2 rad x s(-1) (P < 0.05). Plasma creatine phosphokinase (CPK) activity was greater for the 0 mg x kg(-1) x d(-1) versus the 38 or 76 mg x kg(-1) x d(-1) groups at 48 h after the initial training bout (P < 0.05). In addition, no differences were observed in body fat between the three groups. However, the 38 mg x kg(-1) x d(-1) group exhibited a greater increase in FFM (P < 0.05). CONCLUSIONS: Although the IRM strength gains were not significantly different, HMB supplementation appears to increase peak isometric and various isokinetic torque values, and increase FFM and decrease plasma CPK activity. Lastly, it appears that higher doses of HMB (i.e., > 38 mg x kg(-1) x d(-1)) do not promote strength or FFM gains.

Publication Types:

* Clinical Trial
* Randomized Controlled Trial

 

[al1602]

that was a very good post. I was all set to get some of this stuff. what would you guys recommend?

 

[Singleton]

Just wanted to mention that just because I posted some clinical studies for HMB, does not mean I endorse it!

I have always thought it was too pricey. If I can for $30, I might buy it. 300g @ 9g/ day would last me a month. If the effects aren't noticeable, then it isn't worth it.

 

[Singleton]

a1supplements has it for a decent price.

You can use it @ 8 caps a day for 25 days. This should be enough time to notice an effect.

Let us know how it is.

 

[al1602]

Then what the heck is it used for. THis is like when Ornithine came out.

 

[al1602]

OK, i read up on it.

It is supposed to help protein synthesis and make you get all muscley and stuff....

I wonder what was Mr. Phillips motives were in marketing this stuf ?