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L-glutamine is absolute garbage IMO unless you use it for its immunological boosting properties.
Why is it garbage?
Because the glutamine has to get into the blood stream, thats why.
61% of the amino-acid pool in the blood is glutamine.
Only about 5g of amino acids in the blood at one time(approx.)
About 90%(Probably more) of the ingested glutamine is destroyed by the stomach acids.
After that, its probably safe to assume not even 1% gets to the blood(Probably even less....LOL).
As I said, waste of money.
If you take it for its immune effects(As I do), take it UPON WAKING
with 20g of Baking Soda. You can use Potassium Citrate too.(Animal used to sell this).
The Baking Soda will act as a stomach acid buffering agent and
increase absorption.
I use 20g.(In winter for colds and such)
Tastes damn bad..........
Fonz
Why is it garbage?
Because the glutamine has to get into the blood stream, thats why.
61% of the amino-acid pool in the blood is glutamine.
Only about 5g of amino acids in the blood at one time(approx.)
About 90%(Probably more) of the ingested glutamine is destroyed by the stomach acids.
After that, its probably safe to assume not even 1% gets to the blood(Probably even less....LOL).
As I said, waste of money.
If you take it for its immune effects(As I do), take it UPON WAKING
with 20g of Baking Soda. You can use Potassium Citrate too.(Animal used to sell this).
The Baking Soda will act as a stomach acid buffering agent and
increase absorption.
I use 20g.(In winter for colds and such)
Tastes damn bad..........
Fonz
Fonz, is right with the info but I have to question the reasoning for using it. There are plenty of substances equal to and superior to glutimine for enhancing the immunity system. Why bother with something that's expensive and potentially toxic?
T-Mag came out with a piece dissmissing the effects of glutamine? That's fucking hilareous!!! I wrote an article for them (back in 98', I believe) called "Pills Powder and Potions" where I came out and said glutamine was worthless. They fought me tooth and nail to allow that to remain in the piece. TC made sure not to endorse what I said and refered to it as "the authors opinion that doesn't reflect the opinion of the staff." He then allowed several letters to be printed bashing my statments and questioning my credentials. TC even apologized for what he called "erroneous information" and said he couldn't "catch all the mistakes." Now they come out and say the exact same thing I wrote four years ago and they're thumping themselves on the chest for being so bold and honest. What a bunch of dicks.
They probably agreed to finally print the truth because the information was coming from some kid with a degree in chemistry who's willing to stick his nose up TC's ass.
Thus is the science of the supplement industry.
T-Mag came out with a piece dissmissing the effects of glutamine? That's fucking hilareous!!! I wrote an article for them (back in 98', I believe) called "Pills Powder and Potions" where I came out and said glutamine was worthless. They fought me tooth and nail to allow that to remain in the piece. TC made sure not to endorse what I said and refered to it as "the authors opinion that doesn't reflect the opinion of the staff." He then allowed several letters to be printed bashing my statments and questioning my credentials. TC even apologized for what he called "erroneous information" and said he couldn't "catch all the mistakes." Now they come out and say the exact same thing I wrote four years ago and they're thumping themselves on the chest for being so bold and honest. What a bunch of dicks.
They probably agreed to finally print the truth because the information was coming from some kid with a degree in chemistry who's willing to stick his nose up TC's ass.
Thus is the science of the supplement industry.
Nelson Montana said:
It might be a placebo effect but I have noticed it does ward of colds somewhat.
Besides, its pretty cheap nowadays.
Back in the day it was like $100+/ 500g or something ridicuolus
like that.
And people still bought it....LOL
I'm actually compiling a list of the Top 100 anculliary drugs and supps for performance enhancement right now. Goint to be ruthless........LOL
Glutamine? I give it one star out of five.
Fonz
Fonz: here is a study where plasma glutamine levels were raised 111% percent after oral glutamine supplementation.
jb
===========================================
Nutrition 2002 May;18(5):367-70 Related Articles, Links
Impact of oral L-glutamine on glutathione, glutamine, and glutamate blood levels in volunteers.
Valencia E, Marin A, Hardy G.
Pharmaceutical Nutrition Group, School of Biological and Molecular Sciences, Oxford Brookes University, Oxford, United [email protected]
OBJECTIVE: We investigated the effect of glutamine supplementation on plasma glutamine (Gln), glutamate (Glu), and whole-blood glutathione (GSH) concentrations in human volunteers. METHODS: Subjects first adapted to a standard diet with known intakes of protein, total GSH, cysteine, methionine, and total Glu (Glu values include Glu and Gln) for 3 d. Plasma Gln, Glu, and whole-blood GSH levels were then measured at 4-h intervals over 24 h. Supplemental oral Gln (0.3 g x kg(-1) x d(-1)) was ingested for 10 d and then 24-h plasma levels of Gln, Glu, and whole-blood GSH were measured. RESULTS: The plasma concentrations of Glu (116%; P = 0.006) and Gln (20%; P = 0.046) were significantly higher, whereas concentrations of GSH were significantly lower (37%; P = 0.00091) after oral Gln supplementation. CONCLUSION: Oral Gln increases Glu and Gln levels in plasma of healthy subjects but does not increase GSH red cell (whole-blood) levels. Thus, GSH biosynthesis and preservation of GHS stores in red blood cells may involve rate-limiting substrates other than Gln.
jb
===========================================
Nutrition 2002 May;18(5):367-70 Related Articles, Links
Impact of oral L-glutamine on glutathione, glutamine, and glutamate blood levels in volunteers.
Valencia E, Marin A, Hardy G.
Pharmaceutical Nutrition Group, School of Biological and Molecular Sciences, Oxford Brookes University, Oxford, United [email protected]
OBJECTIVE: We investigated the effect of glutamine supplementation on plasma glutamine (Gln), glutamate (Glu), and whole-blood glutathione (GSH) concentrations in human volunteers. METHODS: Subjects first adapted to a standard diet with known intakes of protein, total GSH, cysteine, methionine, and total Glu (Glu values include Glu and Gln) for 3 d. Plasma Gln, Glu, and whole-blood GSH levels were then measured at 4-h intervals over 24 h. Supplemental oral Gln (0.3 g x kg(-1) x d(-1)) was ingested for 10 d and then 24-h plasma levels of Gln, Glu, and whole-blood GSH were measured. RESULTS: The plasma concentrations of Glu (116%; P = 0.006) and Gln (20%; P = 0.046) were significantly higher, whereas concentrations of GSH were significantly lower (37%; P = 0.00091) after oral Gln supplementation. CONCLUSION: Oral Gln increases Glu and Gln levels in plasma of healthy subjects but does not increase GSH red cell (whole-blood) levels. Thus, GSH biosynthesis and preservation of GHS stores in red blood cells may involve rate-limiting substrates other than Gln.
Fonz said:L-glutamine is absolute garbage IMO unless you use it for its immunological boosting properties.
Why is it garbage?
Because the glutamine has to get into the blood stream, thats why.
61% of the amino-acid pool in the blood is glutamine.
Only about 5g of amino acids in the blood at one time(approx.)
About 90%(Probably more) of the ingested glutamine is destroyed by the stomach acids.
After that, its probably safe to assume not even 1% gets to the blood(Probably even less....LOL).
As I said, waste of money.
If you take it for its immune effects(As I do), take it UPON WAKING
with 20g of Baking Soda. You can use Potassium Citrate too.(Animal used to sell this).
The Baking Soda will act as a stomach acid buffering agent and
increase absorption.
I use 20g.(In winter for colds and such)
Tastes damn bad..........
Fonz
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