MrRTTB said:
Maybe the wrong place to ask, but I need fast info.
I need serious help, it's my mom.
She has lots of problems with inflammations in her feet and arms. The problem is she also has a heart failure and have to take medicine to make her blood thinner. She can not take any medicin for the inflammations like ketoprofen, ketotifen and so on. What I would like to know is if anyone have an idea of any herb or anything with anti-inflammation "abilities/properties". I would then lokk it up and show this to the doc taking care of my mom.
I would really appreciate this.
Fish oil - an example of an anti-inflammatory food.
Cleland LG, James MJ, Keen H, Danda D, Caughey G, Proudman SM.
Department of Endocrinology and Metabolism, Sri Venkateswara Institute of Medical Sciences, Tirupati - 517 507, AP, India.
[email protected].
With regard to anti-inflammatory effects of diet away from the gut, altering the balance of dietary polyunsaturated fatty acids (PUFA) in favour of n-3 PUFA provides the best documented examples of effective dietary intervention. PUFA are essential macronutrients of which there are two non-interchangeable classes, n-6 and n-3. These fatty acids are metabolized to mediators that regulate cardiovascular homeostasis and inflammation. n-6 rich diets tend to be pro-inflammatory and, by comparison diets rich in n-3 PUFA are anti-inflammatory. The difference is explained by the action of n-3 PUFA as competitive inhibitors of enzymes that metabolize n-6 fats and by the lesser biological activities of most n-3 mediators, compared with their n-6 counterparts. Fish oils are a particularly rich source of desirable long chain n-3 PUFA. Fish oil has been used with benefit in the treatment of inflammatory diseases of joints and other organs and tissues. Our long-term studies in rheumatoid arthritis (RA) show that this approach, in conjunction with pharmacotherapy, can be sustained in the long term (>5 years). A potential collateral benefit is reduced risk for adverse cardiovascular events, which are increased in RA. Lack of knowledge amongst physicians of relevant biochemistry, evidence of efficacy, dose response relationships, latency in effect, availability of affordable preparations and tactics for discussing issues efficiently with patients appears to be a barrier to broader clinical use.
PMID: 15778196 [PubMed - in process]
Antioxidant and anti-inflammatory effects of a diet supplemented with sesamin on hepatic ischemia-reperfusion injury in rats.
Utsunomiya T, Shimada M, Rikimaru T, Hasegawa H, Yamashita Y, Hamatsu T, Yamasaki M, Kaku S, Yamada K, Sugimachi K.
Department of Surgery and Science, Graduate School of Medical Science, Kyushu University, Beppu, Japan.
[email protected]
BACKGROUND/AIMS: The antioxidant and anti-inflammatory properties of sesamin (a non-fat constituent of sesame oil) have been attributed to an increased accumulation of dihomo-y-linolenic acid, a precursor of 1-series prostaglandins, and the decreasing production of proinflammatory 2-series prostaglandins and 4-series leukotrienes by inhibiting the delta-5 desaturase activity. We investigated the effects of a diet containing sesamin on hepatic ischemia-reperfusion injury in rats. METHODOLOGY: After feeding rats either a basal diet (control group) or a diet supplemented with sesamin (sesamin group) for 14 days, the rats underwent 60 minutes of partial hepatic ischemia and 3 hours of reperfusion. The phospholipid fatty acid composition of both liver and lung tissue specimens were then analyzed. The plasma levels of leukotriene B4 and PCOOH (phosphatidylcholine hydroperoxide) were also determined. RESULTS: The consumption of the dietary sesamin resulted in a significant increase in the dihomo-y-linolenic acid content in the tissue phospholipids of the liver and lung specimens. The amounts of polyunsaturated fatty acids in the lungs subjected to the ischemia-reperfusion injury were well preserved in the animals from the sesamin group. Despite a lack of differences in the levels of arachidonic acid, the plasma levels of leukotriene B4 in the rats fed dietary sesamin (88 +/- 15 pg) tended to be lower (P = 0.07) than those fed the control diet (110 +/- 20 pg). Furthermore, the plasma concentrations of PCOOH in the sesamin group (130 +/- 62 pmol) were also significantly lower (P < 0.05) than those in the control group (223 +/- 33 pmol). CONCLUSIONS: These findings indicate that a diet containing sesamin may thus reduce hepatic ischemia-reperfusion injury by inducing both antioxidant and anti-inflammatory activities.
PMID: 14571796 [PubMed - indexed for MEDLINE
List of Anti-Inflammatory Herbs:
http://www.uspharmacist.com/index.asp?show=article&page=8_1234.htm
Hope this helps some.
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