Botox only inhibits dynamic wrinkling; scowling, furrowing your brow, laugh lines.... caused by facial expressions. Surface wrinkling is simply a matter of to what degree can free radicals ravage your cells ?
Sun, smoking, nutrition/hydration, sun, stress, sleep, and genetics are the real factors. If we could really buy youth, or extend it for $$, we wouldn't have wealthy old women looking as stretched, pulled, hollow and disappointed as they do.