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Myostat by Biotest
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Triple J
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Most of the research in this area has focused on genetically modified mice. So wether the mice are altered as myostatin knock-outs, or to inhibit myostatin (through increased expression of say forstatin), the lab results came about in mice born with these characteristics.
I am not aware of any studies that demonstrate substances that can transform animals of normal genetics through inhibition of myostatin, say in adulthood. Well, it is not to say it is not possible, I just think that if it were as easy as that, we would have seen some studies or something more significant from the major drug companies. I would bet they are working on this but I just have a hard time believing that Biotest beat them to it.
And plus Biotest even says that the effects will be rather slow-acting (over say a year), so they are basically admitting this is just an experiment (since they have not done any real tests themselves - just rushed the thing to market based on some lab experiments). I'll even go so far as to say they know it will not work, if it were as powerful as they say, there would be too many risks in rushing it to the consumer.
Just think, what would it take to feed the supplement in high amounts to some mice to see the effects?
I am not aware of any studies that demonstrate substances that can transform animals of normal genetics through inhibition of myostatin, say in adulthood. Well, it is not to say it is not possible, I just think that if it were as easy as that, we would have seen some studies or something more significant from the major drug companies. I would bet they are working on this but I just have a hard time believing that Biotest beat them to it.
And plus Biotest even says that the effects will be rather slow-acting (over say a year), so they are basically admitting this is just an experiment (since they have not done any real tests themselves - just rushed the thing to market based on some lab experiments). I'll even go so far as to say they know it will not work, if it were as powerful as they say, there would be too many risks in rushing it to the consumer.
Just think, what would it take to feed the supplement in high amounts to some mice to see the effects?
Last edited:
J said:
Most of the research in this area has focused on genetically modified mice. So wether the mice are altered as myostatin knock
outs, or to inhibit myostatin (through increased expression of say
forstatin), the lab results came about in mice born with these
characteristics.
My reply:
Triple J, I was reading on the John Hopkins website about some scientists who were administering the protein Follastatin (which binds to myostatin) to mice in a lab setting; if I remember correctly, the mice eventually grew just like the "knock out" mice did.
BTW, you can buy follastatin protein from that same lab supply company that sells IGF-1 Long R3 . . . but it's hella expensive needless to say.
Most of the research in this area has focused on genetically modified mice. So wether the mice are altered as myostatin knock
outs, or to inhibit myostatin (through increased expression of say
forstatin), the lab results came about in mice born with these
characteristics.
My reply:
Triple J, I was reading on the John Hopkins website about some scientists who were administering the protein Follastatin (which binds to myostatin) to mice in a lab setting; if I remember correctly, the mice eventually grew just like the "knock out" mice did.
BTW, you can buy follastatin protein from that same lab supply company that sells IGF-1 Long R3 . . . but it's hella expensive needless to say.
Triple J
New member
Fortes said:
I meant to say follastatin in my message, at any rate, we are referring to the same research aricle - the mice were genetically engineered to produce higher than normal amounts of follastatin. So the follastatin was not being administered, it was naturally present in extraordinary amount from pre-birth forward.
Full grown adult males will not benefit from this product. Reduced myostatin levels, as mentioned before, are only going to help muscle wasting patients. This is something Pinnacle sent me to in reference to a question I asked:
First and foremost, we are not claiming that the compound in Juiced Protein (brown sea algae or "fraction C") totally inhibits Myostatin or is responsible for the "mighty mice" and "super bulls". This is only possible (currently) via genetic manipulation.
What we know for sure is that our "fraction C" binds to Myostatin in a chromatography column. That study was carried out only a few months ago by a scientist from the Univ of Madrid. Therefore, it will be some time before the data are published in a peer-reviewed journal. Second, there are TONS more questions than answers about Myostatin, fraction C, and muscle growth. We do have an experiment underway that is verifying whether muscle cells incubated with various concentrations of "fraction C" and Myostatin have increased growth rates.
This in vitro data is an important first step in clarifying the role of fraction C on muscle size in vivo (which will be tackled in a later study).
First and foremost, we are not claiming that the compound in Juiced Protein (brown sea algae or "fraction C") totally inhibits Myostatin or is responsible for the "mighty mice" and "super bulls". This is only possible (currently) via genetic manipulation.
What we know for sure is that our "fraction C" binds to Myostatin in a chromatography column. That study was carried out only a few months ago by a scientist from the Univ of Madrid. Therefore, it will be some time before the data are published in a peer-reviewed journal. Second, there are TONS more questions than answers about Myostatin, fraction C, and muscle growth. We do have an experiment underway that is verifying whether muscle cells incubated with various concentrations of "fraction C" and Myostatin have increased growth rates.
This in vitro data is an important first step in clarifying the role of fraction C on muscle size in vivo (which will be tackled in a later study).
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