Interesting, because I was thinking about this tonite...
Personally; I think one has to be very careful when messing with their hormones, since among the people I know who live in this world tend not to break free (like any other addiction) since they cannot bear to see themselves small again; however ultimately you cannot go on forever so it plays serious games with your head and has serious potential long term health-effects.
Thus I would conclude for some people it is just fine, for others it can wreck them very easily