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Metformin (Glucophage)
- Thread starter Ibiza 06
- Start date
depends what your using it for bro
seems to me it would be best to use before and during a cycle utilizing Slin because of its effects on incresing insulin sensitivity.
shit i can think of alot of ways to use Glucophage
what are your goals, stats, previous experience, cycle history..etc...?
seems to me it would be best to use before and during a cycle utilizing Slin because of its effects on incresing insulin sensitivity.
shit i can think of alot of ways to use Glucophage
what are your goals, stats, previous experience, cycle history..etc...?
Wulfgar said:
ok mate, ive had it in my draw for a while now since i did a fat burn cycle about 1 year ago, clen, T-3,Metformin, yohimburn and Nolvadex.
im going to start a cycle inabout 5 weeks, Test-e,T-bol,Winny and proviron with Anchs, sups etc. Lean mass, want to gain about 7-10 pounds after PCT while loosing a bit BF say 4% ish, im not that bothered about using realy but if it would be of good benifit then i would.
Stats, 5.6", 170lbs,18% Bf ( i know should be about 15% b4 starting cycle but i thought i was,so got all the stuff so fuck it im going for it anyway)
lifting 3.5 years,used primo,winny,T-bol.
Diet clean, training weights and cardio.
Cheers bro.
ok let me ramble for a bit
Glucophage is an anitdiabetic drug used in conjunction with insulin injections to control blood sugar(its used in both type 1 and 2 diabetics.
basically its function is this
1: Increase cell insulin recpetor site number and sensitivity
2: Decrease the amount of glucose/sugar the intestines absorb
3: Decrease the amount of glucose/sugar the liver manufactures. (one source of liver glucose production is amino acids obviously)
stuff works great when used at a dosage of 500-800 mg 1-2 times daily with slin and/or Glipzide tablets
this combo can be potent for causing a increase in carbohydrate requitrements and utilization for a significant weight gain. it also decreases the amount of insulin needed for max results
so there is one way to use it..to gain mass quickly
next:
Pancreatic regeneration: If your using glipzide, glyburide, or other pancreatic/insulin stimulators glucophage will increase the effectiveness dramatically. 500 mg 2 x daily works great here.
its also a great way if you are really trying to set yourself up for serious levels of insulin sensitivty to maximize growth
NEXT!!:
Dieting:
Glucophage utilized during dieting phases works well as a means of decreasing glucose production by the liver and glucose absorbtion by the intestines. this in itself decreases slin secretion by the pancreas and increases the bodies dependence upon fat stores for energy(cool huh?) works great with GH and PGF-2 use as well as there is synergy when employing AAS as well. SINCE cell insulin receptor-sites are more sensitive and since there is an exisiting crossover stimulation between IGF-1 and Insulin(and thier opposing receptor sites) lean mass retention would be increased. this effect helps decrease the negative effects dieting has upon IGF-1 production endogenously.
some notes:
take this stuff with meals and never less than 6 hours before sleeping. Dont take it if you got kidney problems and stacked with 17a orals it could seriously cause some liver damage.
dont take it with a dirutic unles you want to risk heart damage.
careful to watch for signs of lactic acidosis too so DONT DRINK ALCHOHOL FOR GODS SAKE WHILE ON THIS SHIT!!!
good luck bro....
hope that helped
Glucophage is an anitdiabetic drug used in conjunction with insulin injections to control blood sugar(its used in both type 1 and 2 diabetics.
basically its function is this
1: Increase cell insulin recpetor site number and sensitivity
2: Decrease the amount of glucose/sugar the intestines absorb
3: Decrease the amount of glucose/sugar the liver manufactures. (one source of liver glucose production is amino acids obviously)
stuff works great when used at a dosage of 500-800 mg 1-2 times daily with slin and/or Glipzide tablets
this combo can be potent for causing a increase in carbohydrate requitrements and utilization for a significant weight gain. it also decreases the amount of insulin needed for max results
so there is one way to use it..to gain mass quickly
next:
Pancreatic regeneration: If your using glipzide, glyburide, or other pancreatic/insulin stimulators glucophage will increase the effectiveness dramatically. 500 mg 2 x daily works great here.
its also a great way if you are really trying to set yourself up for serious levels of insulin sensitivty to maximize growth
NEXT!!:
Dieting:
Glucophage utilized during dieting phases works well as a means of decreasing glucose production by the liver and glucose absorbtion by the intestines. this in itself decreases slin secretion by the pancreas and increases the bodies dependence upon fat stores for energy(cool huh?) works great with GH and PGF-2 use as well as there is synergy when employing AAS as well. SINCE cell insulin receptor-sites are more sensitive and since there is an exisiting crossover stimulation between IGF-1 and Insulin(and thier opposing receptor sites) lean mass retention would be increased. this effect helps decrease the negative effects dieting has upon IGF-1 production endogenously.
some notes:
take this stuff with meals and never less than 6 hours before sleeping. Dont take it if you got kidney problems and stacked with 17a orals it could seriously cause some liver damage.
dont take it with a dirutic unles you want to risk heart damage.
careful to watch for signs of lactic acidosis too so DONT DRINK ALCHOHOL FOR GODS SAKE WHILE ON THIS SHIT!!!
good luck bro....
hope that helped
It's at the American Diabetes Association's website for Diabetes Magazine. It's a little difficult to understand because the title suggests that ALA was used. But when you scroll down to the Designs and Methods you can see that Asta Medica provided R+ Lipoic Acid for the study.
http://diabetes.diabetesjournals.org/cgi/content/full/50/6/1464
This is the graph showing metformin, avandia, and insulin against R+ (LA). It's pretty amazing that it outperformed insulin itself.
http://diabetes.diabetesjournals.org/cgi/content/full/50/6/1464
This is the graph showing metformin, avandia, and insulin against R+ (LA). It's pretty amazing that it outperformed insulin itself.
read that entire post
Im currently trying to put together if GH/IGF-1/T-3 use would be beneficial to add ALA to instead of Slin itself...
its a slin mimicker for certian in the aspects of pure glucose uptake..does it also shuttle amino acis in the same manner? or its substrates such as creatine and glutamine? and why is it that ALA shuttles glucose strictly to muscle cells? or does it? if it is a slin mimicker that it should also target the slin receptor sites on fat cells right?
where would D-pinitol fit in here? 4-hydroxyisoluecine? Synergy anyone?
lol just some questions off the top of my head
im seeing alot of possible synergy here possibly without the use of slin(or just in very moderate doses...
Im currently trying to put together if GH/IGF-1/T-3 use would be beneficial to add ALA to instead of Slin itself...
its a slin mimicker for certian in the aspects of pure glucose uptake..does it also shuttle amino acis in the same manner? or its substrates such as creatine and glutamine? and why is it that ALA shuttles glucose strictly to muscle cells? or does it? if it is a slin mimicker that it should also target the slin receptor sites on fat cells right?
where would D-pinitol fit in here? 4-hydroxyisoluecine? Synergy anyone?
lol just some questions off the top of my head
im seeing alot of possible synergy here possibly without the use of slin(or just in very moderate doses...
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