I personally run a liver "protectant" all throughout the cycle and after... I gotta be honest, I've used Tylers, Liv52, rALA, NAC...you name it....the bloodwork always comes back the same....liver enzymes usually pretty elevated... would they be worse without the liver protectant? Probably... I still think it's worth taking the precaution... you have to keep in mind that alcohol isn't the only thing that could potentially wreck your liver....you're probably taking other meds, etc. that tax your liver.... even your AI for example... sleeping pills.... OTC pain meds....whatever. Always good to take extra measures to be on the safe(r) side.