Letrozole was studied in men, and found to significantly increase LH levels to a 339 and 323% in the young and the elderly, respectively and Testosterone by 146 and 99%, respectively. (3) Letrozole was also able to produce a peak LH response to Gonadatropin Releasing Hormone equal to a 152 and 52% increase from baseline in either young or older men, respectively (3). In a similar study 0.02 mg of Letrozole increased testosterone by 45% after 2 days. (4) That same twenty micrograms of Letrozole was also enough, in one study done on men, to reduce estrogen levels by roughly a third. (4)