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Letrozole increase testosterone?

Nope..How do you know that? Have you had blood work done?

Letro is is an oral non-steroidal aromatase inhibitor that has been introduced for the adjuvant treatment of hormonally-responsive breast cancer.
Estrogens are produced by the conversion of androgens through the activity of the aromatase enzyme. Letrozole blocks production of estrogens in this way by competitive, reversible binding to the heme of its cytochrome P450 unit. The action is specific, and letrozole does not reduce production of mineralo- or corticosteroids. In contrast, the antiestrogenic action of tamoxifen, the major medical therapy prior to the arrival of aromatase inhibitors, is due to its interfering with the estrogen receptor, rather than inhibiting estrogen production.
 
But I thought if it blocks estrogen that testosterone would rise?


Your right Estrogen is apart of the negative feedback loop of the HPTA are you going to get gains for it nope.




Letrozole was studied in men, and found to significantly increase LH levels to a 339 and 323% in the young and the elderly, respectively and Testosterone by 146 and 99%, respectively. (3) Letrozole was also able to produce a peak LH response to Gonadatropin Releasing Hormone equal to a 152 and 52% increase from baseline in either young or older men, respectively (3). In a similar study 0.02 mg of Letrozole increased testosterone by 45% after 2 days. (4) That same twenty micrograms of Letrozole was also enough, in one study done on men, to reduce estrogen levels by roughly a third. (4)
 
Actually letro, or any AI for that matter, can temporarily increase test because it stops test from converting to estrogen. I always notice a small rise for about a week and then I feel it drop again. If you are looking at it for pct then just go the usual hcg, nolva, clomid, etc.
 
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