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Letro is king!

krishna

New member
Letro is the only AI that actually gets rid of the tenderness in my nips. I remember reading somewhere that it lowers progesterone and prolactin too. Anyone have any info on this? Seems to make sense because it helps with deca gyno too.
 
Your right...it does lower prolactin by some method.....not sure the science on it though. The shit is unreal.....too strong at times unless your running a lot of gear.
 
Vascular Freak said:
Your right...it does lower prolactin by some method.....not sure the science on it though. The shit is unreal.....too strong at times unless your running a lot of gear.

I think because it lowers progesterone which causes prolactin buildup. This shit is a cureall. What are symptoms of it being too strong? Anything I should look out for?
 
letrozole reduces PgR expression, though so do all AI's.

letrozole is just the strongest.

what to look out for is joint dryness and loss of libido, lethargy is also a common symptom of too low estrogen.
 
krishna said:
I think because it lowers progesterone which causes prolactin buildup. This shit is a cureall. What are symptoms of it being too strong? Anything I should look out for?


The main things I noticed are:

Fatigue (similar to an overtrained feeling) if you know
what I mean

Dry joints, similar to winstrol noticed in the elbows wrists and ankles

"Pudding Dick" ..... you get what I mean

Cut it back if you notice that you are very very "dry" but feel "flat" or unable to get a nice full pump while training....it'll feel like you didn't eat enough carbs.

I have ran letro on and off cycle and up to 3.0mg ed! If you are using within a range of 1.25mg - 2.0mg ed you will stay very dry, no nip puffiness, and keep your sex drive.....if you aren't that sensitive then drop it back to 1.0mg ed or about .75cc's if using AG's
 
krishna said:
Letro is the only AI that actually gets rid of the tenderness in my nips. I remember reading somewhere that it lowers progesterone and prolactin too. Anyone have any info on this? Seems to make sense because it helps with deca gyno too.
Letro IS the bomb. My favorite AI by far. Took huge deca gyno away for me when I finally came to the realization that nolva was only making it worse
 
This cycle is the first time I have used letro and it rocks. Had to back it down though because it was killing my sex drive.
 
ive read thats its very effective at a lower dose so i used 1.25/day and got rid of my little sd induced gyno, i will always use it pct now and at 1.25 i had no issues
 
krishna said:
Letro is the only AI that actually gets rid of the tenderness in my nips. I remember reading somewhere that it lowers progesterone and prolactin too. Anyone have any info on this? Seems to make sense because it helps with deca gyno too.


I keep hearing nothing but positive feedback
 
ALIN said:
I keep hearing nothing but positive feedback


then your not listening too close. Letrozole is a great drug and a very potent aromatase inhibitor. Problem is that its often too potent. Actually was just looking at the why of it, which is rather interesting.

common complaints:
dry joints
zero libido
erectile dysfunction
lethargy

really consider letro the "on hand" aromatase inhibitor, though some people can run it for extended periods without issue (some, the super estrogenic types, need to)
 
srf173 said:
I was under the impression that letro would not help tren and deca gyno?


wont is a strong word. it and other AI's are not necessarily effective with tren and nandrolone. how much effect will depend on a lot of factors.
 
macrophage69alpha said:
letrozole reduces PgR expression, though so do all AI's.

letrozole is just the strongest.

what to look out for is joint dryness and loss of libido, lethargy is also a common symptom of too low estrogen.
ya I see a lot of people complaining of joint pain from it.
 
macrophage69alpha said:
wont is a strong word. it and other AI's are not necessarily effective with tren and nandrolone. how much effect will depend on a lot of factors.
So it is a possibility it will help, but that depends on the individual and how much is subjective. I've been following you and harleys arguement but it's a little over my head at this point.
 
he is arguing with himself. Just been correcting his assertions and misinterpretations. anyone that calls nolva "tried and true" is arguing from a mythological standpoint.
 
srf173 said:
So it is a possibility it will help, but that depends on the individual and how much is subjective.


depends on what other hormones are at play, including exogenous one. What impact the progestins are having (as this varies between individuals- receptor isoforms, densities- also those in relation to the other relevant receptor isoforms and densities..etc..etc).


the problem of using letro with tren only is that there is no aromatic conversion and since tren is quite suppressive, how much substrate there will be to block may be insignificant.

though because it will suppress endogenous E synthesis, thus down regulating the PgR, it CAN help. Of course if you are also taking test, EQ, dbol etc... it will help with those driving factors...
 
I got some bb sized lumps in both nips from tren, but no until I ran it 100mg ed. Had letro on hand(no dost though) and ran it at 1.25mg ed to see if it would help or at least keep it from getting worse. It didn't seem to do much and it seemed to just keep getting worse, so I just ended the tren a wk early. Next time I'll just go ahead and get the dost.
 
I had some liquid letro and was running it with dbol among other things. It didnt get rid of any tenderness or anything.

Killing the sex drive was the worst part.
 
problem is that estrogen is not the only enemy out there, even completely crushing it does not mean gyno protected. though there are some that persist in proclaiming this.

lowering estrogen is usually sufficient, but often as not combination therapies are better or necessary.
 
macrophage69alpha said:
problem is that estrogen is not the only enemy out there, even completely crushing it does not mean gyno protected. though there are some that persist in proclaiming this.

lowering estrogen is usually sufficient, but often as not combination therapies are better or necessary.

No one completely understands the mechanisms that cause gyno through AAS use. Unfortunately, it is doubtful that any formal studies will be done regarding the issue. All we have is some good qualitative info from informal case studies and the application of studies done on other populations.

This whole game is a fine tuning process for finding what works best for you - some people around here make some silly proclamations.
 
macrophage69alpha said:
problem is that estrogen is not the only enemy out there, even completely crushing it does not mean gyno protected. though there are some that persist in proclaiming this.

lowering estrogen is usually sufficient, but often as not combination therapies are better or necessary.


macro, care to share your thoughts on "combination therapies" as an alternative to just letro as an ai to reduce/eliminate gyno symtpoms?

and how much gyno is ok.. i mean the letro got rid of my tenderness in the nips, and they haven't really gotten any bigger, but still have a bit smaller than a dime's size of lump. the thing I just noticed though, the sex drive is caput. but what the fuck can I do? I can live with lower sex drive, can't live with titties. sust/deca cycle.
 
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