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ketamine?
- Thread starter Spunky
- Start date
anabolic24/7
New member
There was a thread awhile back about that stuff. The concensus was that it was bad news. I decided not to ever try it.
Digital Ronin
New member
Sure you can sell it... If you get caught, you'll just go to jail for sale of an illegal substance. Last time I checked it falls under "distribution." 
And yes, it's a vetrinary tranquilizer...
And yes, it's a vetrinary tranquilizer...
spentagn
New member
Special K
yeah, it's a tranquilizer. developed partly in response to pcp abuse. promotes sense of euphoria, becoming really popular at clubs and raves. liquid form is usually injected intramuscularly, powder form is often snorted or ingested. very addictive and dangerous. overdose can result in coma and death. other than that, it's a great substance.
yeah, it's a tranquilizer. developed partly in response to pcp abuse. promotes sense of euphoria, becoming really popular at clubs and raves. liquid form is usually injected intramuscularly, powder form is often snorted or ingested. very addictive and dangerous. overdose can result in coma and death. other than that, it's a great substance.
Digital Ronin
New member
Re: Special K
Where did you find this information? Just curious...
spentagn said:
Where did you find this information? Just curious...
Okay..how about this . That's plain stupid. let me tell you briefly about Ketamine and clear up some the partly true statements made here. 1. Ketamine is a potent sedative hypnotic drug that works on the NMDA receptor subtubtype. 2. It blocks polysynaptic reflexes in the spinal cord and inhibits excitatory neurotransmitters in the brain. Enough of that. 3.. It is a COMMON drug used for anesthesia every day for HUMANS. 4. it causes a phenomenon called dissociative anesthesia..simply put, you look awake but cannot respond to sensory stimuli. 5. Side effects: incresed blood pressure, increased heart rate,, combined with opiates (heroin,morphine) it causes respiratory depression (can't breath), in the catecholamine depleted state (low adrenaline..usually people who have been in intensive care unit for weeks..it causes direct cardiac depression( in vitro studies only, not the typical response in normal people.), it also causes bronchodilation and increased salivation. here is the bottom line from an Anesthesiologist/exercise physiologist: So if you do not want to be found dead somewhere, I advise not taking ketamine. Because when your heart rate goes to 150 and your blood pressure shoots through the roof, and that aneurysm in your head you never knew existed ruptures..just remember you took it against medical advise. P.S. Ketamine causes horrible nightmares.
Oh, by the way..all prescription drugs can be either dangerous or safe..it depends on who you give it to, how much you give and how you give it..so the statement it can cause death is true for the reasons I posted. I give it several times a month and have never had a patient have any problems except for a very rare one that complains of nightmares. otherwise it is an excellent drug for the induction and maintenance of anesthesia and sedation for uncomfortable procedures. in the appropriate patient, in the appropriate circumstance it is an excellent MEDICATION to be given by trained practitioners. Alot of people can abuse or use a lot of substances and have absolutely NO problems. On the otherhand, how about Len Bias and his supposed first time use of cocaine.
Your_Moms_Kneepads
New member
Ketamine was made Schedule III in the USA last year. It is likely not scheduled in Canada-YET or other places.animal B said:
Slopain
Banned
Stay away from the shit, I used it a few times its like a mini lsd trip except you cant comprehend shit and communicating is a mess, if you have to do it get yourself on a couch with someone you dont mind looking like a complete dumb ass in front of.
THIS IS VERY HOT, the law sees it as the next X drug trend, and it is targeted. You WILL be seeing it on undercover fox cameras and making all the news. In my opinion leave that to the strung out ones, this has NO USE FOR BODYBUILDERS.
THIS IS VERY HOT, the law sees it as the next X drug trend, and it is targeted. You WILL be seeing it on undercover fox cameras and making all the news. In my opinion leave that to the strung out ones, this has NO USE FOR BODYBUILDERS.
Ketamine is absolutely NOT A LOCAL anesthetic. It is a sedative-hypnotic..not a local anesthetic. Local anesthetics are drugs that work by inhibiting sodium channels therby inhibiting neurtransmission. For example lidocaine, cocaine, bupivicaine, chloroprocaine, prilocaine, mepivicaine, ropivicaine, etc. are local anesthetics. 150 mg is a large dose. Essentially that is 2mg/kg in the normal male patient. That is probably enough to cause the induction of GENERAL anesthesia..ie going to "SLEEP" for surgery. I agree 150 mg in the lay persons hands is lethal..basically without going into alot of details ED 50 is the effective dose of a drug to establish an effect in 50% of the subjects. LD 50 is the lethal dose of a drug that kills 50%. The ED/LD 50 ratio is what is important. This states that the larger the difference between the two doses, the safer the drug is. For example, if 1 mg was the ED 50 and 2 mg was the LD 50, then that drug really sucks ass.
Slopain and Kneepads are Totally Right...
Ketamine was made schedule III last year (i think it was Nov 99).
Everyone in the NYC club scene is currently using this stuff along with X... Its the next best thing to X and together it really gets you going. Take to much and get ready to go in a k-hole. Someone also said that it's not worth much to deal it... NO WAY.. Try getting some in NY and you will pay upto $75 per bottle. You then have to cook it or air it out to convert it to powder form. The Feeling is like a lsd trip. Also your movements became very robotic. IT'S NOT A GOOD DRUG. I'll Tried it many times but will never do it again.
Ketamine was made schedule III last year (i think it was Nov 99).
Everyone in the NYC club scene is currently using this stuff along with X... Its the next best thing to X and together it really gets you going. Take to much and get ready to go in a k-hole. Someone also said that it's not worth much to deal it... NO WAY.. Try getting some in NY and you will pay upto $75 per bottle. You then have to cook it or air it out to convert it to powder form. The Feeling is like a lsd trip. Also your movements became very robotic. IT'S NOT A GOOD DRUG. I'll Tried it many times but will never do it again.
elcorazon:
I did pulled out the ole' canadian compendium and found that both of us are wrong. Thought you might be interrested in the info:
"Ketamine is a cataleptic anealgesic and aneasthetic. It has NO sedative or hypnotic properties distinguishing it from the barbituates" CPS
"The aneasthetic state of ketamine has been dteremined as dissociative in nature in that it appears to selectively interrupt association pathways of the brain before producing somesthetic sensory blockade. It may selectly depress the thalamal neocotical systym before signifgantly obtunding the more ancient cebrral centers and pathways (reticular activiting and limbic systems). " CPS
Ketamine is rapidly absorbed in fatty tissues of the body, making very lipid soluble and easliy passing the blood-brain barrier.
Orally:
The ED50 is skewed when adminstered orally because the method of metabolization is wholly different than the methods recommended for this drug. Oral adminsteration will not induce the same effects as being administered by injection.
Intramuscularly:
The ED50 is :10mg/kilogram
maintenance dose is 10 mg/kg
IV administered:
ED50=2mg/kg
Ketamine has a larghe margin of safety, a dosage given up to ten times has been followed by prolonged and complete recovery.
Ketamine and barbituates are chemically incompatible if they are mixed in a syringe or aministered via the same fashion. The CNS depressants will prolong recovery time if used with babrituates.
Side effects:
Increased BP and puolse rate.
Conculsive seizures
nausea, although minimal
increased salivation
blurred vision
Overdose symptoms:
Respiratory depression
cardiac arrest
Hope this helps!
I did pulled out the ole' canadian compendium and found that both of us are wrong. Thought you might be interrested in the info:
"Ketamine is a cataleptic anealgesic and aneasthetic. It has NO sedative or hypnotic properties distinguishing it from the barbituates" CPS
"The aneasthetic state of ketamine has been dteremined as dissociative in nature in that it appears to selectively interrupt association pathways of the brain before producing somesthetic sensory blockade. It may selectly depress the thalamal neocotical systym before signifgantly obtunding the more ancient cebrral centers and pathways (reticular activiting and limbic systems). " CPS
Ketamine is rapidly absorbed in fatty tissues of the body, making very lipid soluble and easliy passing the blood-brain barrier.
Orally:
The ED50 is skewed when adminstered orally because the method of metabolization is wholly different than the methods recommended for this drug. Oral adminsteration will not induce the same effects as being administered by injection.
Intramuscularly:
The ED50 is :10mg/kilogram
maintenance dose is 10 mg/kg
IV administered:
ED50=2mg/kg
Ketamine has a larghe margin of safety, a dosage given up to ten times has been followed by prolonged and complete recovery.
Ketamine and barbituates are chemically incompatible if they are mixed in a syringe or aministered via the same fashion. The CNS depressants will prolong recovery time if used with babrituates.
Side effects:
Increased BP and puolse rate.
Conculsive seizures
nausea, although minimal
increased salivation
blurred vision
Overdose symptoms:
Respiratory depression
cardiac arrest
Hope this helps!
pgerardone
New member
I can get you cocaine and heroin and you can sell it on your local street corner and probably make more money then selling K in the clubs.
santo smith
New member
send it over Spunky, he he he
guards,
thanks for that info. I was essentially not trying to get into full details about pharmacokinetics and dynamics. Trying to keep it simple. Sedation-and hypnosis are a continuum of degrees of cortical suppression. Most basic anesthesia/pharmacology texts will describe this. I am very right about that. At least my medical boards in anesthesia dictate that. Notice my previous entry about about NMDA receptor activity. Those receptors lie in the regions you cited. also the more ancient brain you describe is better known as the reticular activating system that controls consciousness and sleep. I was trying to keep it simple. Thanks though..the more knowledge the better...learing is a continuous process. I hope this does not sound defensive..i suppose i did not take the time to fully explain or share my knowledge with the board. sorry. Again, it is a safe drug when given by professionals. I did not want to imply it was unsafe for clinical practice. I was trying to explain to others what the term ED 50 was. I give it IV practically every other day. My previous note also mentioned the effects when combined with other drugs(opiates, benzodiazepines, and barbituates) and I previously mentiond the dissociative properties associated with it and discribed it. I also mentioned the nightmares in a previous post. Point well taken though..I will be more complete in my future posts so as not to confuse anyone about my experience and professional expertise with this drug. Thanks for the info.
thanks for that info. I was essentially not trying to get into full details about pharmacokinetics and dynamics. Trying to keep it simple. Sedation-and hypnosis are a continuum of degrees of cortical suppression. Most basic anesthesia/pharmacology texts will describe this. I am very right about that. At least my medical boards in anesthesia dictate that. Notice my previous entry about about NMDA receptor activity. Those receptors lie in the regions you cited. also the more ancient brain you describe is better known as the reticular activating system that controls consciousness and sleep. I was trying to keep it simple. Thanks though..the more knowledge the better...learing is a continuous process. I hope this does not sound defensive..i suppose i did not take the time to fully explain or share my knowledge with the board. sorry. Again, it is a safe drug when given by professionals. I did not want to imply it was unsafe for clinical practice. I was trying to explain to others what the term ED 50 was. I give it IV practically every other day. My previous note also mentioned the effects when combined with other drugs(opiates, benzodiazepines, and barbituates) and I previously mentiond the dissociative properties associated with it and discribed it. I also mentioned the nightmares in a previous post. Point well taken though..I will be more complete in my future posts so as not to confuse anyone about my experience and professional expertise with this drug. Thanks for the info.
F
Frackal
Guest
This is a fucking stupid post that has nothing to do with bodybuilding and will only bring more 'bad' to the board...delete this garbage.
drrman
New member
I'll sound like the drug crazed dumbass here, but i have done K many many times and have had many enjoyable experiences with it. Although i haven't done it in a while, i can tell you it sucks unless you are on X, rolling and a few bumps of K is outrageous. If you are going to inject, i always used a insulin pin to the shoulder and never went over 30 units or so to be safe.
macrophage69alpha
New member
KETAMINE
is virtually the same as PCP
it merely acts as a neurosedative as opposed to a neurostimulant- other wise the effects as well as their chemical structure are virtually identical.
is virtually the same as PCP
it merely acts as a neurosedative as opposed to a neurostimulant- other wise the effects as well as their chemical structure are virtually identical.
macrophage69alpha
New member
well, I am talking about this
PCP and Ketamine are hallucinogenic drugs with anesthetic properties. PCP's chemical name is 1-(1-phencyclohexyl) piperidine. The drug is typically smoked, mixed in powdered form with a leafy substance such as parsley, mint, tobacco, or marijuana; it may also be dissolved in a liquid and sprayed onto the leaves. It also can be injected or inhaled. The effects of PCP depend on the susceptibility of the user and other variables such as mood, dosage, and setting. Effects are evident one to two hours after ingestion and generally last four to six hours. Among chronic users, the reappearance of disorientation and visual, memory, and speech disorders has been noted. The drug accumulates in the body.
As with other hallucinogenic drugs, PCP does not cause physical dependence. In low doses, it produces effects similar to those of LSD, although violent and psychotic behaviour seem to be more characteristic of PCP.
Both Ketamine and PCP have mild effects including feelings of detachment from the surroundings, emotional swings and an altered sense of space and time. Higher doses cause visual distortions and illusions. Users can also feel a separation from their bodies. Most users do not have psychotic episodes, but PCP especially is extremely unpredictable. The PCP user exhibits emotional instability, excited intoxication, lack of coordination, and is often impervious to pain. At high doses, PCP is highly toxic and can cause convulsions and coma.
Physical effects of PCP include high blood pressure, increased deep-tendon muscle reflexes, respiratory depression, dangerously high body temperature and muscle rigidity. The physical effects of Ketamine are similar but are much milder.
Both PCP and ketamine block the actions of the neurotransmittor glutamate at one of its receptors. Glutamate is an inhibatory neurotransmittor. This can cause the feeling of disconnection from body or environment. At the same time, PCP acts like an amphetamine by releasing the neurotransmittor dopamine. This accounts for the excitation, increased energy and activity. This makes PCP have a tremendous overdose hazard and causes users to react unpredictably and hurt themselves. Ketamine does not have this effect on dopamine.
At high doses, PCP is highly toxic and can cause convulsions and coma. Among chronic users, the reappearance of disorientation and visual, memory, and speech disorders has been noted. The drug accumulates in the body. PCP also can cause general anesthesia at high doses, which in turn can lead to dangerously high body temperatures (up to 108 degrees), blood pressure so high it can cause a stroke, breathing can cease, or a prolonged seizure period. Both PCP and ketamine can also cause a prolonged state resembling paranoid schizophrenia.
PCP and Ketamine are hallucinogenic drugs with anesthetic properties. PCP's chemical name is 1-(1-phencyclohexyl) piperidine. The drug is typically smoked, mixed in powdered form with a leafy substance such as parsley, mint, tobacco, or marijuana; it may also be dissolved in a liquid and sprayed onto the leaves. It also can be injected or inhaled. The effects of PCP depend on the susceptibility of the user and other variables such as mood, dosage, and setting. Effects are evident one to two hours after ingestion and generally last four to six hours. Among chronic users, the reappearance of disorientation and visual, memory, and speech disorders has been noted. The drug accumulates in the body.
As with other hallucinogenic drugs, PCP does not cause physical dependence. In low doses, it produces effects similar to those of LSD, although violent and psychotic behaviour seem to be more characteristic of PCP.
Both Ketamine and PCP have mild effects including feelings of detachment from the surroundings, emotional swings and an altered sense of space and time. Higher doses cause visual distortions and illusions. Users can also feel a separation from their bodies. Most users do not have psychotic episodes, but PCP especially is extremely unpredictable. The PCP user exhibits emotional instability, excited intoxication, lack of coordination, and is often impervious to pain. At high doses, PCP is highly toxic and can cause convulsions and coma.
Physical effects of PCP include high blood pressure, increased deep-tendon muscle reflexes, respiratory depression, dangerously high body temperature and muscle rigidity. The physical effects of Ketamine are similar but are much milder.
Both PCP and ketamine block the actions of the neurotransmittor glutamate at one of its receptors. Glutamate is an inhibatory neurotransmittor. This can cause the feeling of disconnection from body or environment. At the same time, PCP acts like an amphetamine by releasing the neurotransmittor dopamine. This accounts for the excitation, increased energy and activity. This makes PCP have a tremendous overdose hazard and causes users to react unpredictably and hurt themselves. Ketamine does not have this effect on dopamine.
At high doses, PCP is highly toxic and can cause convulsions and coma. Among chronic users, the reappearance of disorientation and visual, memory, and speech disorders has been noted. The drug accumulates in the body. PCP also can cause general anesthesia at high doses, which in turn can lead to dangerously high body temperatures (up to 108 degrees), blood pressure so high it can cause a stroke, breathing can cease, or a prolonged seizure period. Both PCP and ketamine can also cause a prolonged state resembling paranoid schizophrenia.
macrophage69alpha
New member
AND THIS
ARYLCYCLOHEXYLAMINES: PCP AND KETAMINE
Phencyclidine (PCP) was developed for analgesics and anaesthetics, but it is now obsolete because of postoperative psychoses. It is still used in veterinary science. It causes sedation, immobility, amnesia and analgesia. The name 'dissociative anaesthesia' is used in this connection.
As an anaesthetic it has been replaced by ketamine (brand name Ketalar) (note 150). This is not a patented product. Ketamine is also manufactured in Hungary and Yugoslavia. PCP and ketamine affect the cortex and the limbic system. Application rapidly brings on analgesia and amnesia. Lack of consciousness lasts 10 to 15 minutes after intravenous application, analgesia lasts 40 minutes, and amnesia can last 1 to 2 hours. Coming round again can take hours, and is sometimes accompanied by unpleasant dreams and hallucinations. Almost 50~ of the persons above 30 experience excitation/delirium or are bothered by visual hallucinations. This is much less common among children and young adults, which is why it is mainly used in child surgery.
Intracerebral pressure, intraocular pressure and cerebral circulation increase. The pharyngeal and laryngeal reflexes remain intact. The coughing reflex is repressed, bronchial resistance is reduced, bronchial spasms are suspended.
There is little relaxation of the muscles, and muscular tension may increase, sometimes accompanied by purposeless movements. Metabolism increases. It has many sideeffects: bizarre and violent behavior, hallucinations, agitation, catatonic rigidity, disorientation, lack of coordination, nystagmus, hypersalivation, vomiting, convulsions, numbness, hypertension, tachycardia, cardiovascular depression is rare. Malign hyperpyrexia with rhabdomolysis resulting in collapse of the kidneys can occur.
The treatment of all toxic symptoms is symptomatic. The toxic psychosis is indistinguishable from schizophrenia. Haloperidol is preferable to chlorpromazine. Acid urine increases the secretion.
There are many contraindications: glaucoma, hypertension, cerebrovascular accident in the case history, heart weakness, increased intracranial pressure, psychiatric deviations, esp. schizophrenia.
It affects the NMDA receptor and inhibits the reuptake of dopamine, serotonin and noradrenaline. Selfinjection behavior occurs among monkeys with PCP.
ARYLCYCLOHEXYLAMINES: PCP AND KETAMINE
Phencyclidine (PCP) was developed for analgesics and anaesthetics, but it is now obsolete because of postoperative psychoses. It is still used in veterinary science. It causes sedation, immobility, amnesia and analgesia. The name 'dissociative anaesthesia' is used in this connection.
As an anaesthetic it has been replaced by ketamine (brand name Ketalar) (note 150). This is not a patented product. Ketamine is also manufactured in Hungary and Yugoslavia. PCP and ketamine affect the cortex and the limbic system. Application rapidly brings on analgesia and amnesia. Lack of consciousness lasts 10 to 15 minutes after intravenous application, analgesia lasts 40 minutes, and amnesia can last 1 to 2 hours. Coming round again can take hours, and is sometimes accompanied by unpleasant dreams and hallucinations. Almost 50~ of the persons above 30 experience excitation/delirium or are bothered by visual hallucinations. This is much less common among children and young adults, which is why it is mainly used in child surgery.
Intracerebral pressure, intraocular pressure and cerebral circulation increase. The pharyngeal and laryngeal reflexes remain intact. The coughing reflex is repressed, bronchial resistance is reduced, bronchial spasms are suspended.
There is little relaxation of the muscles, and muscular tension may increase, sometimes accompanied by purposeless movements. Metabolism increases. It has many sideeffects: bizarre and violent behavior, hallucinations, agitation, catatonic rigidity, disorientation, lack of coordination, nystagmus, hypersalivation, vomiting, convulsions, numbness, hypertension, tachycardia, cardiovascular depression is rare. Malign hyperpyrexia with rhabdomolysis resulting in collapse of the kidneys can occur.
The treatment of all toxic symptoms is symptomatic. The toxic psychosis is indistinguishable from schizophrenia. Haloperidol is preferable to chlorpromazine. Acid urine increases the secretion.
There are many contraindications: glaucoma, hypertension, cerebrovascular accident in the case history, heart weakness, increased intracranial pressure, psychiatric deviations, esp. schizophrenia.
It affects the NMDA receptor and inhibits the reuptake of dopamine, serotonin and noradrenaline. Selfinjection behavior occurs among monkeys with PCP.
ultragainz
New member
his info might be off on this drug shit but on roids i dont think its too off...
macrophage69alpha
New member
PCP and KETAMINE are both ARYLCYCLOHEXYLAMINES
Both are dissociative anaesthetics. Both are based on a phenyl group and a substituted amino group attached to the same cyclohexyl carbon. Ketamine was synthesized in a search for less toxic analogues of PCP. The structural similarity between the two is obvious even to someone who isn't a pharmaceutical chemist. They are different substances, but they're clearly in the same chemical and pharmacological families.
Both are dissociative anaesthetics. Both are based on a phenyl group and a substituted amino group attached to the same cyclohexyl carbon. Ketamine was synthesized in a search for less toxic analogues of PCP. The structural similarity between the two is obvious even to someone who isn't a pharmaceutical chemist. They are different substances, but they're clearly in the same chemical and pharmacological families.
Macrophage great info...I agree with you entirely. Info is 100% on the money. For mor123, I think the reason why I have never used any of the narcotics I give is for several reasons: 1. I have seen firsthand how people react to the drugs..stop breathing (sufentanyl), low blood pressure (fentanyl, morphine), changes in heart (ketamine) and a host of other problems. 2. I seen the idiots who come in through the emergency department at 3 am seizing on cocaine or having a heart attack from it. 3. I KNOW what they do so why would I want to do them. 4. I would lose my job and the respect of my family and friends. I know some docs who have used some of these drugs..and their careers have ended. Its not so easy to steal drugs when your tolerance starts to build up..they go from 1 cc to 10 cc to 20cc..beleive me people noitice when alot of that stuff is missing. The point is this...I will never try that stuff ever..in fact I do not even like takinf ANY medicatons..go figure..a doc who hates to take medicine.
KillerLoop
New member
Did K at the weekend for the first time.....and I doubt I will ever do it again. It is one of those things that is ok once, but that's it. Basically while I was on it I could literally see anything I could think of and it is so real it is scary. I got so bad that I didn't know who my friends were or who I was and I thought I was in a dream that I would never come out of. Very interesting, but never again.
tonystrong
New member
the other day my friend and I got caught using K in Cancun. They thought it was cocaine and wanted to arrest us. They called in the policia to check it out. They did some kind of chemical test and realised it wasn' t coc. so they let us go. The bad thing was that we were so banged up that it didn't even bother us at the time that we could be in a mexican prison
Little Rage
New member
I've tried a few things throughout college but don't do anything anymore b/c i stick to lifting BUT
K - it's not that bad...one of those things u just have to try.
100mg of it made me a little fucked like i was drunk but without the slurred speech.
when i decided to rail 300mg i was fucked
k-Hole is wild, c weird shit, and can't move but only lasts about an hour, but then the milder effects of K lasted for awhile longer...
But for info for u... buy the K, sell 20 bags to stupid Kandy Kids make some money on it and buy more juice
K - it's not that bad...one of those things u just have to try.
100mg of it made me a little fucked like i was drunk but without the slurred speech.
when i decided to rail 300mg i was fucked
k-Hole is wild, c weird shit, and can't move but only lasts about an hour, but then the milder effects of K lasted for awhile longer...But for info for u... buy the K, sell 20 bags to stupid Kandy Kids make some money on it and buy more juice
GearedChupaCabra
New member
I LOVE K
I love the pumps i get from it...i would never inject though...using it the right way could be a lot of fun. BUMP!
I love the pumps i get from it...i would never inject though...using it the right way could be a lot of fun. BUMP!
MaGilicuti
New member
I have heard k is getting big again. But I am not really into the drug scene so I am not that up to date in it. I know that it has been around.
What I have heard though is that Ttokkyo right now is the largest supplier of ketamine. And that people are buying my shirts and wearing them to clubs. Ravers I guess. I guess that is where alot of the mediums are going...
What I have heard though is that Ttokkyo right now is the largest supplier of ketamine. And that people are buying my shirts and wearing them to clubs. Ravers I guess. I guess that is where alot of the mediums are going...
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