Insulin is insulin, but the various types will just kick in sooner or later. Humalog is the fastest, it works within minutes and lasts about 2h. Humulin kicks in around 30min but lasts 4h or so. I've used both, and prefer Humalog cause it leaves your system quicker. Humalog is more dangerous though because it kicks in a lot sooner. If you start feeling dizzy, you'll have less time to do something about it.
WHAT IS INSULIN?
Insulin is a hormone produced in the pancreas- islet cells/beta cells to be specific. Insulin facilitates the use of sugar, which all calories are ultimately converted to, for the multitude of bodily function which include energy production, brain activity, metabolism regulation- basically all of your body's function either directly or indirectly.
WHERE DO I GET IT AND WHAT TYPE DO I USE?
Humilin R is available OTC just about everywhere and while it is a quick acting insulin, it is not the fastest or most consistent in terms of absorption and effect. Humilin R starts working in about ½ hour and the effect can last up to six hours.
Humalog is available OTC in some states/countries while be RX only in many other states. Humalog is a true fast acting insulin which begins activity within 15 minutes and ends activity within 4 hours. Humalog is the preferred insulin to use since it works more predictably and is out of your system faster which makes it easier to control.
HOW MUCH DOES IT COST?
In general, Insulin costs between $20-$30 depending on the type and where you buy it.
WHAT KIND OF NEEDLES DO I USE?
Use 29 gauge, 1/2cc insulin syringes. "B-D ultra-fine" is my preference in terms of brand.
WHERE DO I INJECT?
Upper back of arm, abdomen(avoid area too close to belly button), inner and outer upper thigh, butt cheeks.
HOW DO I INJECT?
Rotate injection sites each time you inject. Don't inject into the same area two times in a row. Insulin injections are subcutaneous- not intramuscular.
WHAT DOSE DO I START WITH?
Start with 2-3 units of insulin. There is no need to start higher than this as you will be adjusting your dose gradually to find a tolerable level.
HOW DO I INCREASE MY DOSE?
To move your dose higher in order to find your ideal dose, go up by one unit per day. A very general guide would be to consider between 10 and 15 units as your pre-determined upper limit. If it turns out you want to go higher and don't have any trouble with those doses, then no harm is done and you can go higher. Don't make big leaps up in dose or assume more is better- be safe rather than sorry.
WHAT DO I EAT AND WHEN DO I EAT IT?
For Humilin R, the general start of activity is within a ½ hour but the varies A LOT!!!!! Don't assume you have tons of time to wait to eat simple sugars. Pay attention to how you feel and never wait more than 15 minutes(if that) to eat. First consume simple sugars(dextrose preferred but not the only one) in the form of some type of drink as these are most readily absorbed in my experience. A general guideline is 10 grams of carbs for each unit of insulin- MINIMUM! Within a hour or so after your dose you want to eat a mix of simple carbs and high protein- this is the golden hour AFTER your workout when the insulin will shuttle nutrients into your muscles very efficiently. Humilin R will peak at two hours after you take it so you must eat another balanced meal at the hour and a half mark approximately. This meal should include complex carbs, some fats, and protein. Use simple carbs also if you feel any hypoglycemic symptoms. "R" will last up to six hours so be aware of how you feel and eat as needed after the two hour mark. REMEMBER THAT YOU STILL HAVE A SIGNIFICANT AMOUNT OF INSULIN WORKING UP TO SIX HOURS LATER SO DON'T BE COMPLACENT AND ASSUME YOU'RE NOT GOING TO GO HYPOGLYCEMIC.
For Humalog, use the same general rules and type of meal sequence, but begin the process immediately. Simple carbs should be ingested within 10 minutes- NO EXCEPTIONS. Then have the carb/protein meal within the hour. Then have the balanced meal of complex carbs/fats/protein at the hour ½ mark. Keep aware of how you feel up to four hours after your dose and eat as needed.
FACTORS AFFECTING INSULIN ABSORPTION/SENSITIVITY
The abdomen is generally the area where insulin is absorbed the most consistently or evenly as it is designed to be.
Injections near a muscle that you have worked out can dramatically increase the absorption rate and effect of your dose of insulin.
GH will make you more insulin insensitive so your tolerance of insulin will change when on or off of GH.
Highly androgenic steroids also make you more insulin insensitive, however, can also cause very random hypoglycemia as well.
Supplements such as Chromium, Ginseng, Alpha Lipoic Acid, and Cinnamon (among others) increase insulin sensitivity.
Variations in glycogen levels in your muscles can also affect how severe a hypoglycemic reactions may be or may feel. If you are starting out with low levels of muscle glycogen, the same dose of insulin that didn't affect you before may now be too much.
The glycogen response from everyone's liver will vary. This hormone increases blood sugar when during stresses to the body or in response to hypoglycemia. Some people may get a big response from their liver and hypoglycemia for them won't be as severe. Others will have less of a response and may be more prone to insulin shock. This response can also vary for each person based on their diet, exercise etc. so don't assume your liver will react the same way to hypoglycemia each time- you may get help from it or you may have to depend mostly on consuming sugar to save your life.
WHAT ARE THE SYMPTOMS OF HYPOGLYCEMIA?
They include: sweating, dizziness, heart palpitations, tremors, drowsiness, sleep disturbance, anxiety, blurred vision, hunger, restlessness, lightheadedness, tingling in extremities, headache, slurred speech, irritability, unstable movement, personality changes, seizures, DEATH
HOW SHOULD I CYCLE INSULIN?
Insulin should be cycled so that you have less of a chance of permanently affecting your own body's production of insulin. Even cycling can affect your own production though so be aware and see your doctor regularly. I say 4 weeks on and 4 weeks off as a general rule of thumb with 6 weeks on being the absolute limit in my opinion.
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This was meant to be a basic introduction to using insulin. I do not condone the use of insulin by non-diabetics nor am I encouraging anyone to use insulin. I am not a doctor and YOU are the only one who can be responsible for making the decision to use insulin. I hope this helps someone to stay safe and think things through before jumping into the unknown. I will be adding things to this as I go since I'm sure I forgot some things.
How to use insulin - the most anabolic hormone
This was originally posted on AF by Juice Junkie.
Directions for first time insulin users
This is an article I wrote a little while ago and posted on several boards. I know it’s a long post but take the time and read it because your life does in fact depend on it. There are a couple other articles on the Anabolic Review board in the Hot Topics Section but I think they all pretty much have the same info.
Let me know if you have any questions
Insulin is the most anabolic hormone you can take. On the other hand its also one of the most dangerous for two reasons availability and ignorance. I will be the first to tell you that every time I have been hypoglycemic (when blood sugar drops to dangerous levels) its has been as a result of something I did wrong. Used responsibility and with respect for the potential sides it is quite safe and extremely effective. That being said we'll start off with what you are going to need.
Equipment:
There are several types of insulin out there but for our purposes we are only interested in two. The first being my favorite Humulin R and the other being a bit newer to the body building community Humalog.
Humulin R is the most widely used and time tested insulin in our arsenal. It has a max duration of 4hrs and its peak can been seen around 2hrs after injection. This becomes particularly important when planning out you meals for the day so keep the timetables in mind.
Humalog is a bit newer but some feel just as effective and a bit safer. Humalog has a max duration of 2hrs and its peak can be seen around 1hr after injection. When selecting to use one or the other keep in mind your schedule, meals, and physical activity for the day as it will all play a role. One other point that needs mentioning is that Humulin R is available over the counter at pretty much every pharmacy in the country for about $25 for 10ml (which will last you a very long time) and Humalog is available only through a prescription or over the black market for a price about double that of Humulin R. When approaching a pharmacist keep in mind that it’s a lot more convincing if you buy the needles at the same time you get the insulin. This way they are less likely to refuse to sell it to you which they have been known to do from time to time. If this should happen just continue on to the next pharmacy and despite what they tell you "you don’t need a prescription" it might be their store policy to see one but legally it is not required and if you make enough of a fuss you will get what you need.
The next thing you will need is the actual needles for injection. These are not the same type that you would use for anabolics or other androgens. The type of needles you will need are U100 insulin needles. That is exactly what you need to say when are trying to buy them. A box of 100 will usually run about $15-$25 and again will last you quite a while. Be fore warned now, using a syringe labeled with cc/ml or anything other than u100 is potentially fatal. The difference between the amount of insulin used for our purpose and that which will kill you is less than ½ a cc.
The next two things I think you will need and I highly recommend having on you is a wrist watch with a chronograph (stopwatch) and glucose tabs and/or a can of soda. First I'll explain the wrist watch. The stop watch is to be started immediately after the injection and monitored periodically to keep track of what is in your body and how long it is active. This can also be used to determine whether or not you are feeling side effects or simply just nerves from the fear that follows using for the first time. For instance I always use Humulin R which we know has a duration of 4 hours and a peak at 2 hours. This means that the greatest effects will be felt somewhere between 1-1/2 to 2 hours after injection and then they will steadily lessen till it is no longer active 4 hours after injection. When you use a stopwatch you have an accurate record of when you felt the effects which will become more important as you get more experienced using insulin. The glucose tabs are your safety net. If you are feeling hypo (hypoglycemic) these tabs will return your blood sugar levels to a safe range where you can get some food. They are available at all pharmacies for about $1.00. I have also used a soda. Soda is high in simple carbs which act quickly when blood sugar is low and allow you to get to a safe range where you can get some food in you. Now that we've covered all the equipment needed to safely use insulin we'll move on to dosage diet and scheduling.
Dosage diet and scheduling:
Whenever you start insulin its always wise to start at a lower dose and taper up over the first couple of days of use. Insulin is still new in our community and there is a potential for becoming diabetic so don’t take chances start small more is not better where insulin is concerned more is simply more fat and more dangerous. This is a schedule I use when just starting insulin:
day1: 5iu's post workout
day2: 6iu's post workout
day3: 7iu's post workout
day4: 8iu's post workout
day5: 9iu's post workout
day6: 10iu's post workout
day7: same as day 6
This concludes week once from here on out this is how I proceed. If I am going to be increasing my dose even further.
day8-10: 10iu's morning, 10iu's post workout
day11-14: 10iu's morning, 10iu's noon, 10iu's post workout
day15 and on: increase post workout dose till I start to feel symptoms of hypoglycemia and then back the dose down accordingly. THIS IS ONLY FOR ADVANCED USERS, DON’T EXCEED THE DAY 7 DOSE TILL YOU GET SOME TIME UNDER YOUR BELT. I AM NOT KIDDING YOU WILL DIE!!!
Your diet will depend on the amount of slin you take per injection. The rule is 10 grams of carbs per IU of insulin. Therefore if you take 10iu's at an injection you need 100 grams of carbs. This is a bit overkill the actual figure is about 5-7 grams but its best to stick with the 10 rule while starting out. I feel that the best most accurate way to consume the proper amount of carbs after an injection is through MRP's or other shakes. The amounts of carbs on these are far more accurate than those you will find on the back of a bread bag. My meals are usually laid out like this:
7am: 10iu's insulin, shake
9am: shake
12pm: 10iu's insulin, lunch
2pm: shake
4pm: shake
6pm: workout
7pm: 10iu's insulin, shake, higher in carbs than others
9pm: dinner
11pm: safe for bed
If you'll notice there is a method to the madness above. After taking your first injection if insulin you will need a shake immediately. After this you are good for the next 2 hrs till the insulin peaks. Once you hit the 2hr mark you will need more carbs either another shake or a meal with sufficient carbs. After you have cleared the 4hr mark you will be clear from danger. Now this is all based on using Humulin R. If you are using Humalog you will need to take your first meal after injection and another "1hr" after. Then after the 2hr mark you will be safe. My shakes are made up of ½ pack of MetRX (berry) and 2 scoops GNC brand weight gainer (vanilla) and 16oz of whole milk. This shake has a caloric value of about 800 cals and around 50grams of protein and 150+grams of carbs. This is a good meal for those starting out. As you progress though you will want to decrease the carbs and eliminate the fat completely to maximize lean mass gains and minimize water and fat retention but for the purposes of starting out simply taking T3 will offset any fat gained. One thing to keep in mind is that T3 will reduce your sensitivity to insulin allowing you to take a higher dose but again save this till you get some more time in.
Side effects and procedures:
After injection and starting your stopwatch your first task is to get some carbs in. Next the first sides you will feel is tired. This is normal and is to be expected. You will usually feel this somewhere between 15-30 minutes after your injection. The key here is not to sleep, if you sleep you wont feel further more dangerous sides and therefore you wont be able to save your ass. The next thing you need to do is have another meal/shake at the 2hr mark. If you miss this just get it in as soon as possible. If you delay long enough you will start to feel hypo around 3 to 3-1/2 hours after injection. When this happens you will feel a sort of numbness that I can only relate to ephedrine. After this you will start to get some shakes in your hands followed by a cold sweat. Once you get to this point you are full blown hypo, the next thing that will follow will be a bit of tunnel vision and this is as far as I’ve been after this its all textbook I imagine coma will follow shortly after passing out. When you get the symptoms listed above don’t hesitate. Get some soda/glucose tabs followed by a meal or shake. One other fact I neglected to mention is that a mix of carbs is necessary when consuming a meal. Simple carbs are used to quickly and complex don’t kick in fast enough. A good mix is the way to go.
This is pretty much a beginners guide to getting started on insulin. If you have any questions either post them on the board or email me. No question is stupid when it comes to a potentially fatal drug.
Ranger