Info on anadrol?

[DiamondCutCows]

Anadrol and dbol are both hard on the liver, and use should be limited to like 6 weeks. Anadrol, in particular, at high doses long-term causes hepatocellular carcinoma (liver cancer). A few cycles is no big deal, but long-term use at high doses is probably suicidal. You can dip into dbol a lot more before big problems arise.

I must have missed the discussion where it was decided about the causing cancer part...Where is the study proving this? Interesting...

 

[majutsu]

Here is just a grab of 10 or so papers and reviews. In getting this for you, I noticed a few things. Methyltest, danazol, and anadrol (oxy) were all three implicated in liver cancer. You see in these refs (#3) that anadrol has even been catalogued by the National Toxicology Program as a Carcinogen, definite type. Lastly, all the fanconi's anemia patients on anadrol really had the tumor problem, so the anadrol magnifies a pre-existing predisposition to cancer. But the non-fa patients who used anadrol also got liver cancer, just less often. The first paper is a 2004 comprehensive review, a good place to start. The last paper is interesting, as it suggests nitrites etc might trigger the cancer potential of anadrol, so you could possibly alter your diet to lower your risk.

I use anadrol. I like anadrol. But I wouldn't be an idiot with it . . . It's like TNT, don't play . . .

1: Velazquez I, Alter BP.
Androgens and liver tumors: Fanconi's anemia and non-Fanconi's conditions.
Am J Hematol. 2004 Nov;77(3):257-67.
PMID: 15495253 [PubMed - in process]

2: Tholouli E, Roulson JA, Byers R, Burton I, Liu Yin JA.
Littoral cell angioma of the spleen in a patient with severe aplastic anaemia.
Haematologica. 2003 Nov;88(11):ECR33.
PMID: 14607765 [PubMed - indexed for MEDLINE]

3: National Toxicology Program .
NTP Toxicology and Carcinogenesis Studies of Oxymetholone (CAS NO. 434-07-1) in
F344/N Rats and Toxicology Studies of Oxymetholone in B6C3F1 Mice (Gavage
Studies).
Natl Toxicol Program Tech Rep Ser. 1999 Aug;485:1-233.
PMID: 12571678 [PubMed - as supplied by publisher]

4: Meadows AT, Naiman JL, Valdes-Dapena M.
Hepatoma associated with androgen therapy for aplastic anemia.
J Pediatr. 1974 Jan;84(1):109-10. Review. No abstract available.
PMID: 12119927 [PubMed - indexed for MEDLINE]

5: Fujino Y, Ku Y, Suzuki Y, Ajiki T, Hasegawa Y, Kuroda Y.
Ampullary carcinoma developing after androgenic steroid therapy for aplastic
anemia: Report of a case.
Surgery. 2001 Apr;129(4):501-3.
PMID: 11283543 [PubMed - indexed for MEDLINE]

6: Nakao A, Sakagami K, Nakata Y, Komazawa K, Amimoto T, Nakashima K, Isozaki
H, Takakura N, Tanaka N.
Multiple hepatic adenomas caused by long-term administration of androgenic
steroids for aplastic anemia in association with familial adenomatous polyposis.
J Gastroenterol. 2000;35(7):557-62.
PMID: 10905366 [PubMed - indexed for MEDLINE]

7: Blanchard KT, Barthel C, French JE, Holden HE, Moretz R, Pack FD, Tennant
RW, Stoll RE.
Transponder-induced sarcoma in the heterozygous p53 mouse.
Toxicol Pathol. 1999 Sep-Oct;27(5):519-27.
PMID: 10528631 [PubMed - indexed for MEDLINE]

8: Stoll RE, Holden HE, Barthel CH, Blanchard KT.
Oxymetholone: III. Evaluation in the p53 transgenic mouse model.
Toxicol Pathol. 1999 Sep-Oct;27(5):513-8.
PMID: 10528630 [PubMed - indexed for MEDLINE]

9: Holden HE, Stoll RE, Blanchard KT.
Oxymetholone: II. Evaluation in the Tg-AC transgenic mouse model for detection
of carcinogens.
Toxicol Pathol. 1999 Sep-Oct;27(5):507-12.
PMID: 10528629 [PubMed - indexed for MEDLINE]

10: Holden HE, Studwell D, Majeska JB.
Oxymetholone: I. Evaluation in a comprehensive battery of genetic toxicology
and in vitro transformation assays.
Toxicol Pathol. 1999 Sep-Oct;27(5):501-6.
PMID: 10528628 [PubMed - indexed for MEDLINE]

11: Kosaka A, Takahashi H, Yajima Y, Tanaka M, Okamura K, Mizumoto R, Katsuta
K.
Hepatocellular carcinoma associated with anabolic steroid therapy: report of a
case and review of the Japanese literature.
J Gastroenterol. 1996 Jun;31(3):450-4. Review.
PMID: 8726841 [PubMed - indexed for MEDLINE]

12: Linares M, Pastor E, Gomez A, Grau E.
Hepatocellular carcinoma and squamous cell carcinoma in a patient with
Fanconi's anemia.
Ann Hematol. 1991 Jul;63(1):54-5.
PMID: 1652289 [PubMed - indexed for MEDLINE]

13: Shimoji N, Imaida K, Hasegawa R, Matsuoka C, Uneyama CT, Takahashi M,
Hayashi Y.
Enhancing effect of oxymetholone, an anabolic steroid, on development of liver
cell foci in rats initiated with N-diethylnitrosamine.
Cancer Lett. 1990 Feb;49(2):165-8.
PMID: 2306710 [PubMed - indexed for MEDLINE]

 

[greekhookup]

i loved anadrol in pill form i had excellent gains all around had little loss after i used it, and now im going to get some of the liquid drol for the winter and try it out, as this helpfull board has informed me that liquid drol is just as good

 

[DiamondCutCows]

Maj, I havent read this yet, but thanks for grabbing that for me!

 

[TheAssholeFomerlyKnownAsDBBT]

Looking for opinions and results/sides of anadrol, thanks for the feedback

you'll get stronger than ever and feel like a freaking animal, then when youre done bye bye go the gains...REALLY bad on the liva