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IGF-1 experiences?

needsize

Elite Mentor
Platinum
I am definitely looking to give it a try on my next cycle, so am looking for personal experiences with it. I know some guys have used the long acting IGF, but I can only get the regular stuff here.
So what were your gains like, how did you use it(my buddy is using it 2x daily, into the body part he in injecting)...
bottom line is I dont know a huge amount about this stuff, but am hearing really good things....and I am not growing from juice anymore, no matter what kind of doses I use...
 
goingon4t or whatever can help you out bro

regular IGF is a waste bro get lr3 it from a research website you can find some for CHEAP
 
holy ghost said:
goingon4t or whatever can help you out bro

regular IGF is a waste bro get lr3 it from a research website you can find some for CHEAP

Corretamundo!!!
Don't waste your money on regular IGF!
You need the IGF-1 LR-3. If you can't get it than don't waste your money. Seriously, the regular IGF is not the same thing and will actually have some negative sides because you will want to up the dose or try to shoot to often. I haven't tried my guy to see if he is still around as I am in the middle of test. prop. and what to see the full cycle clean. Well except for the GH.
No that I think about it, when I was researching it the straight IGF is almost impossible to get. So I think, am not sure, your source is not clear on what they have. Either way IGF is kinda like GH in the handling. If you get powdered in the small 100mcg vials you are far better off than the 1000mcg preconstituted ones. If you have any more questions. I will be around.
 
needsize said:
I am definitely looking to give it a try on my next cycle, so am looking for personal experiences with it. I know some guys have used the long acting IGF, but I can only get the regular stuff here.
So what were your gains like, how did you use it(my buddy is using it 2x daily, into the body part he in injecting)...
bottom line is I dont know a huge amount about this stuff, but am hearing really good things....and I am not growing from juice anymore, no matter what kind of doses I use...

Your gains will be nothing like the long acting stuff. What do you mean my here? Don't you know about NAFTA and free trade? JK
Gains were great, no I take that back, sick. Muscle growing ontop of muscle. I don't know the protocall your body is using, might be he does not have the LR-3. With the LR-3 it was in last muscle group worked out start out with 25-30mcg's per side (left bi/right bi). I had to move my work out around so that Tri's, bi's and delts were last. With the long acting you really only need it 3x per week. But IMMEDIATELY PWO! Than take some Vitagro 15 min later your shit will blow up. And the cool thing is it doesn't just go away. In fact that is why I started with the prop. I wanted to get some nasty thickness going then after hit the IGF. The only downside I noticed was I did not have the strength gain to go with the muscle size! You don't bloat up either. It was great stuff.
 
And its not illegal to possess. YET!
 
wow bro, thats what I was hoping to hear! I stopped growing from gear a few years ago, for the last 2 years I have done insane cycles, along with 7+ meals a day, and dont think I have gained more than a pound or two. So this is sort of my last kick at the can to add more size.
This is a cut and paste from one of my sources lists

IGF – LYPHOLIZED POWDER
one vial, 1 mg/ vial- comes with acetic acid to mix with

I have another one I can get it from, would have to double check the brand name. I am in canada, so I'm not sure if I can get ahold of any legit LR-3 around here, so thats why I was asking about the other kind
 
needsize said:
wow bro, thats what I was hoping to hear! I stopped growing from gear a few years ago, for the last 2 years I have done insane cycles, along with 7+ meals a day, and dont think I have gained more than a pound or two. So this is sort of my last kick at the can to add more size.
This is a cut and paste from one of my sources lists

IGF – LYPHOLIZED POWDER
one vial, 1 mg/ vial- comes with acetic acid to mix with


I have another one I can get it from, would have to double check the brand name. I am in canada, so I'm not sure if I can get ahold of any legit LR-3 around here, so thats why I was asking about the other kind

yup,

that works fine... you want to shoot it post workout into the muscle worked, its good during pct because it keeps you realtivly lean and increasing your hunger...

Needsize IGF as a stand alone wont do much imo at your size 60 (low) -120mcg would be the standard dose...

My advise would be to run a basic peptide cycle... (slin is optinal) bare with me as write this down from memory...
 
You will certainly want to tweak this for your particular application, but this should at least get you headed in the right direction.

THE CYCLE

Weeks 1 and week 20-30 – HGH – On 5/ off 2
Weeks 1-5, 11-15, 21-25
• 2 – 3 IU’s - first thing in the morning on workout days – early afternoon on non-workout days
Weeks 6-10, 16-20, 26-30
• 2 – 3 IU’s first thing in the morning
• 2 – 3 IU’s 1-2 p.m. or pre-workout (or IM post-workout with your insulin if preferred)


Weeks 1-5, 11-15, (21-25) – IGF-1 – Every day
80 – 100 mcg’s intramuscular
• post work out on workout days
• first thing in the morning on non-workout days

Slin you want to do 4 on.. break for about 4-6 weeks then 4 on again.
Weeks 6-10, 16-20, (26-30) – Humalog – Workout days only
• 8 – 12 IU’s immediately post workout, intramuscular

IMPORTANT / CRITICAL - Post Insulin Nutrient Routine
Immediately after Humalog injection – do the following in exacting fashion -
• Injection + 5 minutes – drink shake with 10g glutamine / 10g creatine / 7 grams of dextrose per IU of Insulin. (If you don’t wish to split the shakes, add the whey isolate described as well here for a single shake).
• Injection + 15 minutes – drink shake with 65g of whey isolate protein in water (skip if taken with above)
• Injection + 75 minutes – eat a protein / carb meal with 40-50g of protein, 40-50g of carbs, NO FATS (you may wish to add another 30g or so whey isolate protein drink with this meal if you have tore down sufficient muscle groups to utilize this without it being stored as fat)
(i.e. – two boneless, skinless chicken breasts baked or grilled, a serving of brown rice, sweet potatoes, or pasta, with green beans)
Avoid fats for 2-3 hours for Humalog IM, 3-4 hours for Humalog subQ, 4-5 hours for Humulin-R.
keep some glucose tablets or other simple carbs on hand (Orange Juice, Full sugar Coke, etc.) for the active window of your insulin. Hypo symptoms can and will hit hard and fast and you will have little time to react. This is the main danger of insulin use. . Lack of attention to detail in this area can end in a nice ambulance ride, a visit to the hospital or even a one-way trip to the morgue. Be ready and act smart. The price of stupidity is really, really high.

OPTIONAL Addition to above cycle

Weeks 1- (20-30) T3 or T4 - Every Day
one of the following –
• 12.5 mcgs - 25 mcgs T3 taken once each day
-or –
• 100 mcgs T4 taken once each day

[alternative method if additional fat loss is necessary - Only use if sufficient anabolic androgenic steroids cycle is present to protect and support lean tissue and use only during the weeks of LR3 injections to avoid any potential negative impact to our IGF levels by increased IGF binding proteins. The 13 amino acid side chain of LR3 IGF-1 has specifically been engineered to resist being impressed by or bound to IGFBP’s, so any increase in the below ramp up/down will not kill your IGF levels. A reasonable dose AAS component of the cycle will further protect lean tissue from being used for fuel. In absence of these above-mentioned components, you won’t want to run your T3 above 50mcgs per day. It will begin to elevate IGFBP’s and will dismantle and burn through hard-earned muscle proteins quicker than you could imagine.]

Weeks 1-5, 11-15, (21-25) T3 Every Day
For each of the 5 week runs of T3:
Days 1-3 25 mcgs
Days 4-6 50 mcgs
Days 7-9 75 mcgs
Days 10 - 20 100 mcgs
Days 21 - 24 75 mcgs
Days 25 - 27 50 mcgs
Days 28 - 30 25 mcgs
Days 31 - 35 12.5 mcgs

DESCRIPTION OF THE ELEMENTS OF THIS CYCLE


IGF-1
When HGH makes it pass through the liver, a release of IGF-1 is a result. IGF-1 appears to be a key player in muscle growth. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues. While HGH will cause an increase in your IGF-1 level over the course of a few months, HGH has a cumulative effect, so our addition of IGF-1 will greatly speed up the time to results.

There are two types of IGF-1 that will typically be used by bodybuilders. One is bio-identical huIGF-1, a 70 amino acid string. The other is Long R3 IGF-1, which is an 83 amino acid analog of human IGF-I comprising the complete human IGF-I sequence with the substitution of an Arg for the Glu at position 3 (hence R3), and a 13 amino acid extension peptide at the N-terminus (hence the long). This 13 amino acid "side chain" helps prevent the IGF-1 from being so easily bound by binding proteins, and thus increases its active window exponentially. Which of these you use depends on your goal.

HuIGF-1 is very short lived in the body (probable half life of approximately 10 minutes). This type of IGF-1 is very useful if you are seeking local site growth. Since it is so short lived, little if any of the IGF-1 makes it to other tissues and IGF-1 receptors in other parts of the body. The way to inject this is immediately post work out into the muscle that you wish to have local site growth. Use a U100 insulin syringe, and inject 100 - 300 mcg’s (in some cases more) bilaterally into the desired muscle immediately post workout. For this type of IGF-1, I would use it workout days only.

For Long R3 IGF-1, it isn’t as critical that you inject into a local site as long R3 has a active window of many hours (if not days), and is designed specifically to resist being bound by IGF binding proteins.

Since it is common to reconstitute this type of IGF-1 with Benzyl Alcohol, Acetic Acid, or Hydrochloric Acid, I would still recommend that you inject intra-muscular. While for some purposes of nerve regrowth and other medical recovery purposes subQ is a somewhat superior injection method, it can and probably will leave a nice red irritated spot for a couple of weeks if you inject subQ, and it is not superior for our purposes of muscle growth anyway.

I still inject into a muscle just worked to take advantage of increased IGF-1 receptors present as a result of tearing down muscles with my workout, but because of the long activity window of this type of IGF-1 any muscle will work well and give you good results. I would suggest that you inject between 80 – 120 mcg’s per day everyday immediately post workout on workout days, and first thing in the morning on non-workout days.

The added bonus of using LR3 in our cycle is that fat loss will be accomplished while still eating a great number of clean calories per day. You will visibly see yourself leaning out from a couple of weeks in on while using LR3 at doses suggested here.

Use a U-100 insulin syringe with 1/2" needle to inject IGF-1 intramuscular (bilaterally for HuIGF-1, bilaterally optional for Long R3)

Insulin

Insulin is very good at shuttling nutrients to the muscles, and works in a very complimentary manner with GH in the types of things that they shuttle. Also, HGH can cause an amount of insulin resistance, so adding some insulin to your cycle will go a long ways toward reducing the elevated blood glucose levels caused by HGH's action of interfering with the liver's ability to uptake glucose, and thus help offset any potential resistance that might occur during your HGH cycle. Also by taking our HGH near the time of our insulin injection (immediately post workout) we are ensuring a great influx of growth factors after action on the liver. HGH + insulin passed through the liver = BIG secretion of growth factors. These growth factors will equate to muscle growth, rapid healing, etc.

For the purposes that we are using insulin, a dosage of 6-12IU’s is adequate and should be used immediately post workout. I personally prefer using Humalog intramuscular as it will cause a rapid spike and clear out of your system quickly. You can use it subQ or use Humulin-R instead, but each of these will result in a longer active window, thus a longer time to avoid eating any fats and watching your carb intake. Any fats or over abundance of carbs will end up being stored as fat during insulin's active window. The approximate windows are:
Humalog - IM - 2-3 hours
Sub-q - 3-4 hours
Humulin -R - IM - 3-4 hours
Sub-q 4-5 hours

Use a U-100 insulin syringe with 1/2" needle to inject IM immediately post workout. Alternatively, you can inject subQ if desired or if you wish a longer active window for some reason. Begin with a dose of 4IU's or so, and increase the dose each workout day until you reach your desired 8-12IU's.

If for some reason you wish to avoid insulin, I would still suggest that immediately post workout you spike you own endogenous insulin by drinking 80 grams of dextrose / 40 grams of whey isolate protein. While this certainly won't do the work of 8-12 IU's of Humalog, it will most certainly assist getting your muscle back in a nitrogen positive environment in a short amount of time.




Also another consideration if cycling in higher doses, cycle your T3 in conjunction with your LR3 IGF-1 use. The thought behind this is that LR3 binds poorly to IGFBP's, so you will be able to use an elevated dose of T3 (which will likely increase IGFBP's) and still keep elevated IGF-1 levels. I would suggest that use of T3 above 25mcg's or T4 at doses above 100mcgs or so would not be advisable for too many 5 weeks segments of your complete cycle. As one of the major "anabolic" benefits of HGH use is elevated IGF-1 levels, we don't want to create an environment of radically increased IGF binding proteins. Abuse of T3 or T4 will go a long way in creating that environment hostile to IGF-1.
 
Bro, if that's you in your addy...you don't need any more size. Holy shit!
Are you training for Jay's job? Lookin' good!
 
some great info there too fez, gonna have to read it a few times to digest it all
I do plan on running this as part of a heavy cycle
So far this is my plan, but its definitely open to input as I am still learning about IGF
my cycles tend to be around 12 weeks in length
weeks 1-2 heavy test, deca, dbol, and maybe some eq
weeks 1-4 IGF-1
weeks 4-8 gh with insulin
weeks 8-12 IGF-1
I could stretch this out and change the length any way I needed to
I have run insulin tons of times in the past, humalog and humalin r(ran "r" 2x a day on my last try and didnt notice any gains) Figured if I ran it with gh, I might see better growth from it, and could use it for longer periods during the day without worrying about fat gain
 
halfcenturian said:
Bro, if that's you in your addy...you don't need any more size. Holy shit!
Are you training for Jay's job? Lookin' good!

that is me, it was taken 2 weeks ago, but thats maybe 192-195lbs in stage at 5'8", not bad, but I want more, and cant get there with juice alone, so this seems to be my best shot at gaining more
 
no prob with gh and slin you will see results ..
with anabloics im hearing nothing but good things from it. I know two people that ran it the gh slin combo and added about 10lbs solid...
8gh/10 slin post workout
 
ahhh i knew i had some more info on gh slin

Ok we all know the basic functions of the two hormones, Growth Hormone, and Insulin. I'm just going to point out the relation they have to muscle cells and fat cells.

Insulin promotes the creation of fat cells (lipogenesis)
Growth Hormone fosters the destruction of fat cells (lipolysis)

Growth Hormone counters the effects of insulin. The way it works is this. Insulin is a kind of automatic garage door opener, letting glucose, amino acids, and fats enter the cells. Growth Hormone blunts the receptivity of fat cells to insulin, in effect blocking the electric eye of the garage door opener. By constantly opposing the action of insulin, youthful levels of Growth Hormone keep the cells thin. Without Growth Hormone to inhibit the effects of insulin, the fat cells are free to expand.

Restoring the GH-Insulin balance.

When we are young, our levels of GH are high in relation to insulin. This is good because as we've discussed above, insulin works to create fat cells, while GH works to break down fat for use as energy. GH acts as a brake on insulin, keeping it's fat creation and storage at a minimum. This is why when you were young, you could pig out on pizza and fries and shakes all you wanted without paying the consequences.

Now let's look at what happens when you age. Starting around your mid to late thirties, even in the twenties for some people, you start to put on fat even though your diet and physical activity haven't changed. The reason is that the balance between GH and insulin has shifted. GH has declined while insulin, if anything, has remained the same or even gone up. Insulin is an essential hormone required for the metabolism of sugar. Without it, we die. Insulin also stimulates muscle growth but to a much lesser extent than GH. But with less GH around, insulin is free to turn every calorie you don't immediately expend into fat for later use. Insulin and GH are both our friends; it is the balance between them that is the problem. by bringing GH back to youthful levels--not beyond, which could have negative effects--we can restore the balance between GH and insulin so that they both work together. In this way, when GH and insulin are both in the bloodstream together, they help to stimulate protein synthesis and muscle mass growth. At the same time the higher levels of GH work to block insulin's fat storage effect. And during the postabsorptive phase (which i will discuss in a minute) when insulin disappears from the blood stream, GH can melt away fat without interference.

The Feast-Fast Cycle

The best explanation i can give for how GH works to reduce weight and build muscle is this: With every meal, we go through a three stage cycle of feast and fast. In the first hour after eating (stage 1), the blood sugar rises and insulin is released, which encourages the storage of excess carbs and fat. After the second hour (stage 2), GH is released and the levels of insulin and blood sugar start to fall. At this stage, GH acts to build up muscle protein, an activity that is enhanced by the presence of insulin. In stage 3, known as the postabsorptive phase, which occurs more than 4 hours after eating (the fasting stage), the GH concentrations remain at high levels, while the insulin almost disappears. At this stage, GH acts solely to mobilize the body's fat stores for burning fuel.

To take advantage of the feast fast cycle, you would have to space your meals and snacks so that they are between four and five hours apart. This time interval will allow the insulin to disappear from your bloodstream so that the GH can work unimpeded to build muscle and lean body tissue. This is why i suggest those of you who are using GH for the sake of fat loss and take a.m shots, to try and keep your carb meal as far away from the GH shot as possible.

Mechanism of Fat Loss

Growth Hormone accelerates the burning of fat by making it available as fuel. It is like taking wood from the shed and putting it on the fire. By increasing the free fatty acids, GH makes the fat stores available for energy production. Injections of GH can reduce both the size and amount of fat cells.

Fat cells have GH receptors, and when the GH binds to the receptors, it triggers a series of enzymatic reactions in the cell to break down fat. This as we discussed earlier is called lipolysis. The hormone also gets rid of fat by increasing the energy expenditure overall so that you actually burn more calories faster--a neat metabolic trick.

That's about as plain and simple as i can make it without going into to much detail or specifics.
 
slat1 said:
I believe the regular stuff is only active for 8 to 10 minutes in the body!

igf1lr3 IS ACTIVE FOR several hours in the body,,,regular IGF1,,just briefly
 
seems like the doses of gh are lower than what I have heard...seems I keep hearing i need 8-10iu a day to grow, which I cant afford, but 3iu or so a day isnt bad, if it produces results
 
I dunno bro,

at your size 3 ius wont add any real sides.. I think you need up ward 8-10.. 1-3iu's is primalilry for longetivity/fatloss purposes...

Just use some cheaper blues ;)
 
The half life for LR-3 is 6-10 hours for regular IGF the half life is 10 min hope that helps you understand why you need the LR-3.
 
I actually just found a source for gh that makes it much more affordable, I still want to try IGF but gh is looking attractive again
Has anyone here tried those generic blue tops? They are definitely cheap, just wondering on experiences with them?
 
holy ghost said:
wtf that shit is fake bro sorry to break it to you!

Come on Holy that was a joke, I love those websites...
Lying bastards. GH and IGF in a spray what a joke!!!
Oh and it has LR-2 in it too. I thought you would get a laugh out of that!!!
 
needsize said:
I actually just found a source for gh - growth hormone (somatropin) - that makes it much more affordable, I still want to try IGF but gh - growth hormone (somatropin) - is looking attractive again
Has anyone here tried those generic blue tops? They are definitely cheap, just wondering on experiences with them?


ygpm!

also the blue-depends on your source some people carry shitty blues others carry some decent quality ones...
 
Faizakafez said:
I dunno bro,

at your size 3 ius wont add any real sides.. I think you need up ward 8-10.. 1-3iu's is primalilry for longetivity/fatloss purposes...

Just use some cheaper blues ;)

I am friendly with some guys that do routines, diets and gear for pro's and national level superheavies.
4iu's it the most I have seen them recomend.
Everyone is different though as I have heard in Germany they are using 16iu's.
 
it also depends on the the type most pro's are usuing the premier stuff

Jino etc... right...but i do agreee with you...its not set in stone...
 
Most pro's have maxed themselves out and don't need much to maintain.
Who knows what they did to get to that point though.
Its still mostly stuffing down the whole foods and making sure your blood is not deficient in certain vitamins and minerals.
I have noticed it tends to be the "no name" pros who use tons and tons of stuff.
That is probably just explained by genetics or the fact that some turn pro at 150lbs and are trying to compete at 190 to 200.
 
turns out it was LR3 that all my guys had on their lists, you can tell I hadnt reseached this much
I have 1000iu on the way to try, looking forward to it
 
Can someone elaborate more on the dosing of the IGF-1 LR3....I saw 20-30mcg per side and only three days a week...Do you run this through your whole cycle? Best for bulking/cutting ? Similar to taking growth? How long do you have to run it to see results?
 
I am wondering about dosing, I have heard take it on training days, some say before workout, some say afterwards...I train 4-5 days a week, do I want to take it all 5 days, etc....
 
40mcg is plenty. We have to realize that this is a huge amount compared to what the body naturally produces. what the actual amount produced by a normal human, say even with exercise, but it's probably something less than 1mcg.

25-30 mcg each side. 40 each side in the quads. That's plenty. Now, you won't see major, immediate LBM increases, but THAT IS NOT WHAT IGF-1 IS FOR. That's what anabolic steroids are for. 40-50mcg total will let you get plenty of hyperplasia, not grow your intestines too much, and save you plenty of $. The newly added muscle cells will take months to grow, but they will, and you will use IGF-1 again because it gets reasonably inexpensive with such a protocol.

Another thing: much of the newer research shows that EOD and even E3D igf-1 treatment is better than ED because ED makes the IGF-1 lose its effect too rapidly. It is still unknown wether this effect comes from receptor downregulation or depletion .Either way, it takes some time for the effects to come back in full after a bout of ED IGF-1 treatment. So you may want to think about switching to EOD lifting and IGF-1 immediately postworkout every workout, or 2on/1off and pin the lagging muscle E3D. These dosing patterns won't give you pounds of immediate muscle, but they will give you hyperplasia , which means continued growth at very decent rates, and the ability to continue treatment for a long while until response diminishes.
 
Faizakafez said:
40mcg is plenty. We have to realize that this is a huge amount compared to what the body naturally produces. what the actual amount produced by a normal human, say even with exercise, but it's probably something less than 1mcg.

25-30 mcg each side. 40 each side in the quads. That's plenty. Now, you won't see major, immediate LBM increases, but THAT IS NOT WHAT IGF-1 IS FOR. That's what anabolic steroids are for. 40-50mcg total will let you get plenty of hyperplasia, not grow your intestines too much, and save you plenty of $. The newly added muscle cells will take months to grow, but they will, and you will use IGF-1 again because it gets reasonably inexpensive with such a protocol.

Another thing: much of the newer research shows that EOD and even E3D igf-1 treatment is better than ED because ED makes the IGF-1 lose its effect too rapidly. It is still unknown wether this effect comes from receptor downregulation or depletion .Either way, it takes some time for the effects to come back in full after a bout of ED IGF-1 treatment. So you may want to think about switching to EOD lifting and IGF-1 immediately postworkout every workout, or 2on/1off and pin the lagging muscle E3D. These dosing patterns won't give you pounds of immediate muscle, but they will give you hyperplasia , which means continued growth at very decent rates, and the ability to continue treatment for a long while until response diminishes.

some great info faiz, thanks
You also get the fat loss effects as well too right?
I am still on gh, currently 3iu eod, I was planning on staying on it during IGF, but dropping it to maybe 2iu eod just to keep it in my system. It seems like since i have been on it for 12 weeks or so now, I am seeing more effects(positive) even though my dose is way lower
This was just going to be a trial run on IGF to see how I respond, and plan out my next mass phase, likely after christmas, so I was only figuring on around 4 weeks, then give my body a month or so, then hitting up the mass phase...If i like the IGF, I am going to start with that, if not, I was going to ramp the gh up higher, and add in insulin
With work, its hard to change my workout schedule around too much, I am thinking maybe hitting the IGF on mon, tues, thurs, fri, which are my usual training days
 
and just wondering, why shoot post workout, why not before?
 
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