eh, short version, as i gather (and i know little, so check out the website at www.dermacrine.com or one of the various threads on the aas board for more info), is that it has some good stuff like DHEA and pregnenolone, which convert to various chemicals/hormones upon absorption through the skin and subsequent metabolism by the body. notable metabolites include test and progesterone. purported benefits/uses include muscle-building, fat-loss, "improved" brain function, "boosted" immune function, aromatase inhibition.