Alone GH is most effective for individuals greater then 35+...
To run GH without insulin, T3 and some heavy AAS it is not strongly anabolic and really only an effective fat burner (a very expensive one and not worth it).
If you don't run it with the above, instead spend your money on a kick-ass AAS cycle.
GH is safe as well as insulin if you do your homework...
It is like scuba diving... You follow the rules and no problem...
You get complacent and fuck up -- it could kill you.
Do a search on insulin and/or HGH on this board and you will find a ton of information.