Please Scroll Down to See Forums Below i used, and am about to use w/ the 1st 1/2 of my upcoming cycle, AG letro, then switch to AIFM. how safe is this stuff? how difficult is it to make? i'm just wondering after reading the thread on guy w/ liver tumors from high estrogen, and how some only trust HG anti estrogens. only HG anti e's i have access to are arimadex, proviron and nolva. i use proviron but not nolva, and i like letro so much better than arimadex. plus i get raped on arimadex. i need something like letro or AIFM since i am prone to gyno like symptoms when using test.
how safe are research ancillaries?
- Thread starter hanibal
- Start date
GymIntensity
New member
bro, an anti-e is something such as nolvadex. AI's or aromatase inhibitors are letrozole, aromasin, and arimidex. If you weren't successful with liquidex, try aromasin. From what ive researched, aromasin is in between strengths of arimidex and letro. Alot of guys only keep letro for serious situations and just keep it on hand. Also letro can kill your sex drive, and also cause rebound side effects because of how strong it is. Aromasin is more preferable for a daily AI. AIFM is also very similar to aromasin and the makers of AIFM also recommend aromasin equally for the most part. I have aromasin and aifm.
GymIntensity
New member
and as far as safety bro, you want to definately go with a legitimate reseach company to assure you get great quality and accuracy of dosing. I dont think the process is difficult, but with careless production, you could have bad results and sides with inaccurate dosing. AG guys seems to have good quality IMO.
hanibal said:
What exactly are you concerned about? Inherent health issues or inaccurately dosed gear? Cause Id trust AG guys are accurate enough.…
The only real safety issue that comes to mind from letro is the over suppression of estrogen, and wreckage of the cholesterol profile. If you continue the letro usage for many weeks or months you will find your HDL levels non-existent, making you extremely prone to heart disease.
I don’t think liver toxitity is an issue with letro, but it very well could be an issue with nolva and clomid. I wouldn’t be concerned about proviron liver toxitity, but then again, its not really my favorite PCT drug to begin with.
-Pp
i am concerned w/ health issues of research company stuff. i know AG is reputable but i still worry, even so about UG AS. i always try to use HG gear, when i can which doesn't seem too often. the letro would be used 8 weeks, 1 mg EOD, then onto AIFM for 8 weeks left of cycle, and into and beyond PCT some.
hanibal said:
What AAS's are you running? That is a hell of a lot of estrogen suppression...
-Pp
No liver issues with nolva, clomid or proviron. Nolva is given to women at 20mgs ed for years after breast cancer. Men have used clomid just as long and Ive seen studies on proviron usage up to a year and a half at high doses with no problems.
Research products are basically suspended in propolene gycol and you would have to drink 8oz. of the stuff to just get the runs.
No worries.
Research products are basically suspended in propolene gycol and you would have to drink 8oz. of the stuff to just get the runs.
No worries.
galaxy said:
Being that clomid and nolva are FDA approved drugs does not make them safe by any means. Tamoxifen only temporarily wards off breast cancer in women, and puts women at greater risk for endometrial cancer.
Clomid and Nolva have definite toxicity issues -
Biotransformation of the Antiestrogen Clomiphene to Chemically Reactive Metabolites in the Immature Female Rat
Peter C. Ruenitz, Richard F. Arrendale, Garry D. George, Carolyn B. Thompson, Corwin M. Mokler, and Nitin T. Nanavati
Cancer Res., Aug 1987; 47: 4015 - 4019.
Antiestrogens and the formation of DNA damage in rats: a comparison.
Kim SY, Suzuki N, Laxmi YR, Umemoto A, Matsuda T, Shibutani S.
Chem Res Toxicol. 2006 Jun;19(6):852-8.
Activation of 4-hydroxytamoxifen and the tamoxifen derivative metabolite E by uterine peroxidase to form DNA adducts: Comparison with DNA adducts formed in the uterus of Sprague-Dawley rats treated with tamoxifen
Deena N. Pathak, Krisztina Pongracz, and William J. Bodell
Carcinogenesis, Sep 1996; 17: 1785 - 1790
Activation of the Tamoxifen Derivative Metabolite E to Form DNA Adducts: Comparison with the Adducts Formed by Microsomal Activation of Tamoxifen
Krisztina Pongracz, Deena N. Pathak, Takemichi Nakamura, Alma L. Burlingame, and William J. Bodell
Cancer Res., Jul 1995; 55: 3012 - 3015.
Teratogenic effects of clomiphene, tamoxifen, and diethylstilbestrol on the developing human female genital tract.
GR Cunha, O Taguchi, R Namikawa, Y Nishizuka, and SJ Robboy
Hum Pathol, Nov 1987; 18(11): 1132-43.
Granted, men who use these SERM’s are not immediately dropping dead from liver cancer, I still prefer not to use them.
-Pp
GymIntensity
New member
hanibal said:
bro, i ordered my aromasin from AG guys. did they discontinue it or something? haven't been on there site in a while...
GymIntensity
New member
hanibal said:
not as strong as letro, but then again aromasin doesn't hurt your cholesterol profile, if anything it helps it . letro is for serious serious cases of gyno or guys that are majorly prone to it. not something you want to run ED throughout cycle usually. aromasin you can run ED or EOD to keep bloat and estro down. stronger than Arimidex but weaker than LETRO. like i said TOO MUCH strength is bad and will cause an estro rebound thus giving you more estrogen than before. honestly I would probably only consider letro if i actually HAD gyno. AIFM / aromasin seem to be the happy medium. honestly on my cyc ive only used AIFM , havent even used my AG aromasin yet. I think im going to save that for PCT or maybe a couple weeks before pct.
