It's kind of long explaination but to be brief
The hypothalamus at the brain is responsible for giving signals to the pituitary gland to start producing Gonadotrophins releasing hormone a.k.a GnRH, this hormone increase the production of Luteinizing hormone resuling in givnig signals to the testicles to produce Testosterone by chemical reactions throw leydig cells
While using Excessive amount of Steroids, it gives negative feedbacks to the hypothalamus therefor interrupts it's job from sending signals to the pituitary to complete the process of boosting/making Testosterone
HCG works as a synthetic Luteinizing hormone which will gives signals directly to the testicles to produce Testosterone but at the same time, being a synthetic exogenous hormone will results in sending negative feedbacks to the hypothalamus, therefor HCG's effects is just temproary but in fact HCG inhibit natural Testosterone production same as Steroids
while Clomid's mechanism, it send positive feedbacks to the hypothalamus by inhibiting Estrogen receptors at this area, therefor the hypothalamus will start working better and as Clomid being a non-steroidal hormone and works by the feedbacks mechanism therefor it will never inhibit the HPTA if compared to HCG
Hello Waem,
I read your posts and I can see you have a great knowledge in this field. Therefore I would like to ask your opinion on this:
HPTA Restoration
I've done 2 cycles:
1st cycle: Summer 2010, 12 weeks of Sustanon only (500 mg a week)
2nd cycle: Summer 2011, 12 weeks of Test Cyp E + Deca
PCT for both cycles was Clomid und Nolvadex at the end (no HCG).
For the first cycle everything worked out well. For the 2nd cycle I noticed my testicles did not return to normal size. I thought with time it would go back to normal but testicles stayed small. In addition, semen volumen stayed reduced (a few drops comprared to what it was).
I haven't touched any gear in 1 year and things stayed the same. Now I'm thinking I should do something to get my testicle back in size/shape and also increase my semen volume.
I had some bloodwork done and these are the results:
Testosterone: 476 (Range 241 - 830 ng/dl)
FSH: 1.6 (Range 1.1 - 13.3 mIU/ml)
LH: 3.1 (Range 1.4 - 9.4 mlU/ml)
PL: 6.7 (Range 2.1 - 17.7 ng/ml)
E2: 31 (Range until 40 < 40)
Age: 29 years old
FSH is very low and I think that's why my ejaculate volume is so small.
I was thinking about running the following:
250 iu -- HCG (twice a week)
75 iu --- HMG (once a week)
Bit I'm not sure if that's OK? is it too much or too less? for how long? how much Arimedex or Nolvadex should I run during to keep estrogens in check and at what dose? when should I start Clomid and at what dose and for fow long?
I appreciate your help