Ghrelin is adipogenic. It stimulates not only the appetite, but the storage of bodyfat. Yes, it stimulates gh - growth hormone (somatropin) - release, but that's secondary to the fact that it makes you fat. Not just any kind of fat, but will likely make you a fat bastard pretty quickly.
Anyone who is using Ghrelin is absurdly and grossly misinformed about what it does. I bet it's popular where some misguided and ill-informed research chem company (or source) advertises (wherever that is) AND quotes studies to the members of that site, showing that it increases GH levels. But they (likely) do not also tell them that this stuff is also adipogenic.
Just a hunch.
Int J Biochem Cell Biol. 2007 May 3; [Epub ahead of print] Links
Ghrelin: A new peptide regulating growth hormone release and food intake.
De Vriese C, Delporte C.
Laboratory of Biological Chemistry and Nutrition, Université Libre de Bruxelles, Brussels, Belgium.
Ghrelin, identified as an endogenous ligand for the growth hormone secretagogue receptor, is a 28 amino acid peptide hormone possessing an unusual octanoyl group on the serine in position 3, crucial for its biological activity. Ghrelin is predominantly produced by the stomach but also by many other tissues such as pituitary, hypothalamus, duodenum, jejunum, ileum, colon, lung, heart, pancreas, kidney, and testis. In addition to stimulation of GH release,, ghrelin stimulates appetite and food intake, enhancing fat mass deposition and weight gain. Besides these main actions, ghrelin regulates gastric motility and acid secretion, exerts cardiovascular and anti-inflammatory effects, modulates cell proliferation and influences endocrine and exocrine pancreatic secretion, as well as glucose and lipid metabolism. Therefore, ghrelin agonists and antagonists might be valuable for some clinical aspects.
PMID: 17544318 [PubMed - as supplied by publisher]
Oh boy! Enhance my fat mass! Sign me up right now!
Anyone using Ghrelin is ignorant to what it actually is, or grossly mislead by whomever is selling it.