Getting rid of love handels

[macrophage69alpha]

This website http://www.mesobeaute.com/lipodissolve.htm seems to say that Phosphatidylcholine is the active ingredient that dissolves fat. If it isn't, what would be the purpose of Phosphatidylcholine?

how about you get the real story here.... their website is less than forthcoming.. though it can be said that phosphatidylcholine may have some impact

Dermatol Surg. 2004 Jul;30(7):1001-8. Links
Detergent effects of sodium deoxycholate are a major feature of an injectable phosphatidylcholine formulation used for localized fat dissolution.Rotunda AM, Suzuki H, Moy RL, Kolodney MS.
Division of Dermatology, University of California Los Angeles, David Geffen School of Medicine, Los Angeles, California, USA.

BACKGROUND: Phosphatidylcholine injections are becoming an increasingly popular technique to treat localized fat accumulation. This formula is composed primarily of phosphatidylcholine and sodium deoxycholate, a bile salt used to solubilize the natural phospholipid in water. The mechanism through which this injectable phosphatidylcholine formulation causes localized fat reduction is unknown. OBJECTIVE: To investigate the active component and mechanism of action of an injectable phosphatidylcholine formulation in clinical use. METHODS: Cell viability and cell membrane lysis assays were performed on cell cultures and porcine skin after treatment with the phosphatidylcholine formula, isolated sodium deoxycholate, or common laboratory detergents Triton-X 100 and Empigen BB. In addition, we described the histologic changes after injection of these substances into porcine tissue. RESULTS: A significant and comparable loss of cell viability, cell membrane lysis, and disruption of fat and muscle architecture was seen in cell cultures and tissue specimens treated with the phosphatidylcholine formula and isolated sodium deoxycholate. These findings were similar to the effects produced after treatment with laboratory detergents. CONCLUSIONS: The phosphatidylcholine formula popularly used in subcutaneous injections for fat dissolution works primarily as a detergent causing nonspecific lysis of cell membranes. Our findings suggest that sodium deoxycholate is the major active component responsible for cell lysis. Detergent substances may have a role in eliminating unwanted adipose tissue. It is advised that physicians use caution until adequate safety data are available.

Dermatol Surg. 2006 Apr;32(4):465-80. Links
Mesotherapy and phosphatidylcholine injections: historical clarification and review.Rotunda AM, Kolodney MS.
Department of Dermatology, University of Southern California School of Medicine, Los Angeles, California, USA. [email protected]

BACKGROUND: Mesotherapy was originally conceived in Europe as a method of utilizing cutaneous injections containing a mixture of compounds for the treatment of local medical and cosmetic conditions. Although mesotherapy was traditionally employed for pain relief, its cosmetic applications, particularly fat and cellulite removal, have recently received attention in the United States. Another treatment for localized fat reduction, which was popularized in Brazil and uses injections of phosphatidylcholine, has been erroneously considered synonymous with mesotherapy. Despite their attraction as purported "fat-dissolving" injections, the safety and efficacy of these novel cosmetic treatments remain ambiguous to most patients and physicians. OBJECTIVE: To distinguish mesotherapy from phosphatidylcholine injections by reviewing their history and the relevant experimental or clinical findings. METHODS: A comprehensive search of Medline indexed literature and conference proceedings. RESULTS: All the published studies evaluating the clinical efficacy of traditional mesotherapy currently originate from Europe. These reports focus primarily on musculoskeletal pain and vascular disease, rather than cosmetic applications. Although experimental data suggest that a number of traditional mesotherapy ingredients may theoretically reduce fat, these effects have not been supported in peer-reviewed studies. An increasing number of reports demonstrate that subcutaneous injections of a formula containing phosphatidylcholine combined with its emulsifier, deoxycholate, are effective in removing small collections of adipose tissue. Cell lysis, resulting from the detergent action of deoxycholate, may account for this clinical effect. CONCLUSIONS: Mesotherapy is distinct from a method of treating adipose tissue with subcutaneous injections of deoxycholate alone or in combination with phosphatidylcholine. Additional clinical and experimental studies are necessary to more definitively establish the safety and efficacy of these treatments.

 

[td1111]

Interesting: "This formula is composed primarily of phosphatidylcholine and sodium deoxycholate, a bile salt used to solubilize the natural phospholipid in water."

"An increasing number of reports demonstrate that subcutaneous injections of a formula containing phosphatidylcholine combined with its emulsifier, deoxycholate, are effective in removing small collections of adipose tissue. Cell lysis, resulting from the detergent action of deoxycholate, may account for this clinical effect."

Do you guys suppose that the Liquid Phosphatidylcholine at http://www.researchchemist.com/product/0209061.html requires the addition of deoxycholate to be effecive, or does it being a liquid already suggest it has already been made soluble in this liquid? A member on SE said he had success using the Phosphatidylcholine alone, although from a different supplier.

 

[Twoguns]

that's horrible advice bro!

funny, that is what I am going to try this spring.

 

[52_21_30]

Not for anything, but this guys situation (original poster) is what liposuction was really designed for. Not rich women who eat and drink themselves into a stupor and have botox parties on Friday nights when their husbands are off banging girls their daughters' age. No, lipo is really best for those who are very lean elsewhere on their frame, but have stubborn fat pockets. This is also (from everything I've read), what YES was designed for. So I'd say that if YES and GH didn't get you to where you wanted to be, go for lipo. There's no shame in it. I can't tell you how many guys i know who are competitive bber's, male entertainers, models, etc who've had some form of plastic surgery whether it be lipo, pec sculpting, etc. If you're committed to the a healthy lifestyle and keeping the weight off, I'd say it's a great investment.