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Canker sore: Causes - MayoClinic.com
Canker sore
ARTICLE SECTIONS
* Definition
* Symptoms
* Causes
* Risk factors
* When to seek medical advice
* Tests and diagnosis
* Treatments and drugs
* Prevention
* Lifestyle and home remedies
Causes
The precise cause of canker sores remains unclear, though researchers suspect that a combination of several factors contributes to outbreaks, even in a single individual. These factors include:
* A faulty immune system that attacks healthy cells in your mouth instead of pathogens such as viruses and bacteria
* A minor injury to your mouth from dental work, overzealous brushing, sports mishaps, spicy or acidic foods, or an accidental cheek bite
* An allergic response to certain bacteria in your mouth
* Helicobacter pylori, the same bacteria that cause peptic ulcers
* A diet lacking in vitamin B-12, zinc, folate (folic acid) or iron
* Celiac disease, a serious intestinal disorder caused by a sensitivity to gluten, a protein found in most grains
* Inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis
* Behcet's disease, a rare disorder that causes inflammation throughout the body, including the mouth
* HIV/AIDS, which suppresses the immune system
* Food allergies or sensitivities
* Certain foods, particularly chocolate, coffee, strawberries, eggs, nuts, cheese and highly acidic foods, such as pineapple
* Hormonal shifts during menstruation
* Emotional stress
* Toothpastes and mouth rinses containing sodium lauryl sulfate