diflucan & gear???

[supergirl]

Here is a question for ya gurus out there... while on gear can you take diflucan (pill) or a tioconazole (cream) to battle yeast infections (caused by gear in my case)... Are there possible interactions???
thanks

 

[Little Girl]

Thanks sg, you stole my question!!!
LG

 

[supergirl]

LOL @ littlegirl.... hey as long as we get the answers we need!!!

 

[BigEasy]

Per Medline.com:




TIOCONAZOLE VAGINAL
Drug Interactions

Drug-Drug Interactions from First DataBank


These drug interactions are reviewed by an editorial panel at First DataBank and determined to be clinically significant.The list does not include every interaction ever reported.


Contraindicated
None listed
Severe
None listed
Moderate
AZOLE ANTIFUNGAL AGENTS/RIFAMYCINS
CYCLOSPORINE/AZOLE ANTIFUNGAL AGENTS


Drug-Food Interactions from First DataBank



Most Significant
None listed
More Significant
None listed
Significant
None listed
Less Significant
None listed
Minor Significance
None listed

Drug Interactions from AHFS DI™



Since only small amounts of tioconazole are absorbed systemically following intravaginal administration, drug interactions are unlikely in patients receiving the single-dose intravaginal regimen used in the treatment of vulvovaginal candidiasis

While results of animal studies indicate that tioconazole may induce hepatic cytochrome P-450 isoenzymes and the drug therefore theoretically could induce the metabolism of drugs metabolized by these enzymes, it is unlikely that such drug interactions could occur with intravaginal tioconazole.

Results of clinical studies indicate that efficacy of intravaginal tioconazole is not affected by concomitant use of oral contraceptives

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Hope that helps~

BE

 

[cockdezl]

As posted, the cream will not enter the blood stream to any extent, but the Diflucan orally may cause alterations in the cytochrome P450 systems. This could pose problems with any oral steroids, since they are known to alter this same system. Non-17-alkylated steroids (injectables) don't seem to alter this system and would be better choices.