Dermacrine doesn't boost natural test. It is slightly suppressive. It will increase circulating anabolic hormones, including test, as it's a transdermal delivery system for DHEA and Pregnenolone, which can eventually convert to testosterone.
By personal experience on it was very positive. Slightly increased strength, slightly reduced BF and probably 3 pounds of lean mass, which was easily keepable.
In my book, for a product with almost no sides (for me), it's well worth running...