supernav said:
>In all types of cancer....I would recommend r-ala
That's a *HUGE* statement dude. Can you site studies that have come to this conclusion? (preferably a link or organization). If it's above, you'll have to translate. No way i can understand that.
-= nav =-
Link...organization? Its called medline. They have a massiver archive of data.
Read this...and I'll explain below.
1: Leukemia 1997 Sep;11(9):1546-53 Related Articles, Links
Induction of the differentiation of HL-60 promyelocytic leukemia cells by vitamin E and other antioxidants in combination with low levels of vitamin D3: possible relationship to NF-kappaB.
Sokoloski JA, Hodnick WF, Mayne ST, Cinquina C, Kim CS, Sartorelli AC.
Department of Pharmacology, Cancer Center, Yale University School of Medicine, New Haven, CT 06520, USA.
Epidemiological studies have provided evidence that diets rich in antioxidant nutrients may reduce the risk of cancer. To evaluate the possibility that dietary phytochemicals with antioxidant potential would create an environment capable of affecting the differentiation of HL-60 leukemia cells, we measured the effects of vitamin E and other dietary antioxidants on the differentiation produced by low levels of vitamin D3 and analogs thereof. Vitamin E succinate and other antioxidant compounds (ie butylated hydroxyanisole, beta-carotene and lipoic acid) used alone had no significant effect on the differentiation of HL-60 cells; however, these agents markedly increased the differentiation produced by vitamin D3. Previous studies from this laboratory have shown that a sequence-specific antisense phosphorothioate oligonucleotide to the Rel A subunit of NF-kappaB enhanced the differentiation of HL-60 cells produced by several inducing agents. Consistent with these observations, vitamin E succinate caused a marked reduction in the nuclear content of NF-kappaB both in the presence and absence of vitamin D3.
Check:
These findings suggest that NF-kappaB may be a factor in regulating the differentiation of myeloid leukemia cells.
The results also indicate that combinations of vitamin D3 and analogs thereof with dietary antioxidants may be useful in overcoming the differentiation block present in acute promyelocytic leukemia cells.
PMID: 9305611 [PubMed - indexed for MEDLINE]
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This is just one study that shows that NF-Kappa B is an important factor in the differentiation(multiplication) of cancerous(Leukemic in this case) cells.
R-ala has been shown to be a very potent de-activator of the NF-Kappa B function.
If you do a search, you will find that many, many sites say the same thing....ALA is a potent de-activator of the NF-Kappa B function.
If you also do a search...you will find a post by me on chat detailing what supplements are beneficial for people w/ cancer and why.
Fonz