Something I read I while back:
"Since Dianabol's half life time is only 3.2-4.5 hours 1 application at least twice a day is necessary to achieve a somewhat even concentration of the substance in the blood. Scientific tests continue to show that on days of intense workout compared to rest days, the half-life time of Dianabol is reduced even further so that an application three times daily appears sensible. Since Dianabol is also 17-alpha alkylated and thus largely protected against a loss in effect, it is recommended that the tablets be taken during meals so that possible gastrointestinal pains can be avoided. On the third day after discontinuing the intake of Dianabol, proof of the substance methandrostenolone (methandienone) in the blood is negative. This means that the tablets are no longer effective. The athlete, however, should not proceed under the assumption that a urine test will be negative since the elimination of the metabolites of the substance methandrostenolone through the urine continues much longer. The maximum substance concentration of Dianabol reaches the blood after 1-3 hours. A simple application of only 10 mg results in a 5-fold inerease in the average testosterone concentration in the male (2). An important reason why Dianabol works well in all athletes is that the endogenous cortisone production is reduced by 50-70%. Thus, Dianabol considerably slows down the rate at which protein is broken down in the muscle cell."
"Although Dianabol has many potential side effects, they are rare with a dosage of up to 20 mg/day. Since Dianabol is 17-alpha alkylated it causes a considerable strain on the liver. In high dosages and over a longer period of time, Dianabol is liver-toxic. Even a dosage of only 10 mg/day can inerease the liver values; after discontinuance of the drug, however, the values return to normal. Since Dianabol quickly inereases the body weight due to high water retention, a high blood pressure and a faster heartbeat can occur, sometimes requiring the intake of an antihypertensive drug such as Catapresan. Additive intake of Nolvadex and Proviron might be necessary as well, since Dianabol strongly converts into estrogens and in some athletes causes gynecomastia ("bitch tits") or worsens an already existing condition. Because of the strongly androgenic component and the conversion into dihydrotestosterone. Dianabol has significant influence on the endogenous testosterone level. Studies have shown that the intake of 20 mg Dianabol/day over 10 days reduces the testosterone level by 30-40% (3). This can be explained by Dianabol's distinct antigonadotropic effect, meaning that it inhibits the release of the gonadotropic FSH (follicle stimulating hormone) and LH (luteinizing hormone) by the hypophysis. Another disadvantage is that,after discontinuance of the compound, a considerable loss of strength and mass often occurs since the water stored during the intake is again exereted by the body. In high dosages of 5O mg+/ day aggressive behavior in the user can occasionally be ebserved which, if it only refers to his workout, can be an advantage. In order to avoid uncontrolled actions, those who have a tendency to easily lose their temper should be aware of this characteristic when taking a high D-bol dosage."
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