combating progesterone sides??

[needsize]

My next cycle is combining, among other things, 2 progesterone based drugs, deca and anadrol? I know anti-e's like arimidex dont stop the sides from those, namely gyno which is the only one I'm worried about. I know bromo is supposed to block progesterone, but i was reading up on it in the CPS and it blocks the production of growth hormone, which I obviously dont want. Are there any other drugs that I can use instead?

 

[MUSTANG_18]

I am pretty sure RU-486 would work for what your looking for but it is VERY hard to find and expensive when you do find it What your next cycle look like bud ? I was thinking Deca-Enanthate-Drol sometime along the line as well.

M18

 

[psychedout]

I am pretty sure RU-486 would work for what your looking for but it is VERY hard to find and expensive when you do find it What your next cycle look like bud ? I was thinking Deca-Enanthate-Drol sometime along the line as well.

M18

It will work, but its has brutal sides as to my knowledge. manny knows all about them.

 

[BigAndy69]

Say hello to my little friend DOSTINEX.

 

[MUSTANG_18]

I know Fonz used it as well when he did his high dose Deca cycle so he could be another person to talk to about how it worked for him

M18

 

[BigAndy69]

M18, nobody uses RU 486 bro. Right around the time you took a break from the boards, I know it was the newest thing and EVERYBODY was excited. It turned out to be a very dangerous substance with a whole host of side effects such as blood in your stools. It's not an option

 

[Testopro one]

winny is said to be anti-progestagenic

 

[needsize]

the cycle is enth, deca, eq, and anadrol for the first 4 weeks. Ru486 is definitely not an option

 

[DeepZenPill]

Unexpected death is one of the sides of RU-486. Definitely something that is completely not worth using.

 

[Mavy]

Winny!

 

[jerkbox]

why EQ and Deca?

 

[needsize]

Winny!

I dont want to add any more AAS to my cycle, and I dont use winny anyway, too hard on the joints and the hair

jerkbox, I am using eq and deca because they are both anabolic but work in very different ways

 

[OfimNedu]

Winny certainly does NOT battle progesterone.

Quote from Nandi12:
"There really isn't any published research to speak of on non-aromatising AAS and gyno. If non-aromatising AAS do cause gyno it could be via suppression of natural testosterone production. This would lower DHT levels, and DHT seems to have several antiestrogenic actions, as well as being effective at treating gyno. Many researchers attribute gyno to a lowered (T+DHT)/E ratio rather than simply a lowered T/E ratio.

It's also possible that elevated IGF-1 from AAS could contribute to gyno. Anavar elevates hepatically derived IGF-1 by increasing GH production. And many androgens seem capable of stimulating local IGF-1 production.

BTW, winstrol has exactly the same effect as does progesterone in the study bodybuilders always cite as evidence to the contrary. That is the impression given by the wording of the abstract. The paper is clear in that winstrol is a progesterone receptor AGONIST."

I never had a problem with gyno until I added winny to my Prop/Tren cycle.

 

[needsize]

thanks OfimNedu

 

[calveless wonder]

whats dostinex?

 

[zziggzzigg]

dostinex aka cabergoline

used as a prolactin reducing agent similar to bromocriptine but with less side effects

 

[Testopro one]

. First of all it's a 5-alpha reduced substrate. 5-alpha reduction breaks the double bond between positions 4 and 5, which is required for conversion to estrogen via aromatase, the primary enzyme for the manufacture of estrogen in males. Because some of these compounds nonetheless show some affinity for aromatase they may have some use in blocking estrogen from other steroids they are stacked with. Wether or not Winny acts in this way is not entirely sure. What has been a popular point of discussion with stanozolol is its suggested anti-progestagenic effects. The theory goes that Winny can bind and compete for a position at the progesterone receptor much like Clomid of Nolvadex would at the estrogen receptor, thereby inhibiting progestagenic effects. Now, progesterone can aggravate estrogenic side-effects by agonizing estrogen and it does play a role in gyno.

 

[b1ewsw32]

My next cycle is combining, among other things, 2 progesterone based drugs, deca and anadrol? I know anti-e's like arimidex dont stop the sides from those, namely gyno which is the only one I'm worried about. I know bromo is supposed to block progesterone, but i was reading up on it in the CPS and it blocks the production of growth hormone, which I obviously dont want. Are there any other drugs that I can use instead?

Anadrol is not a progesterone based drug. I think it's a DHT based one. Deca-D's progestogenic effects can be controlled with RU486(mifepristone)-not recommended! and stanozolol...try 50mgs eod as this dose shouldn't cause too much joint problems.

Tamoxifen should be the agent of choice for anadrol induced gyno..20-40mgs/day and a light diuretic dose for any unwanted bloat.

It has been suggested that the estrogenic effects of oxymetholone may not be as much mediated by estrogen, as by oxymetholone itself activating the estrogen receptor. Because there is little to no aromatisation off oxymetholone, the possible progestational effect was examined first. Similar to that of nandrolone perhaps. But a study2 testing the progestational effects of oxymetholone and methandrostenolone against those of testosterone as well as nandrolone and its metabolites showed that the progestagenic activity of oxymetholone wasn't even in the neighbourhood of that of testosterone, let alone nandrolone. Ruling out the possibility of progestagenic activity and aromatisation, that only left oxymetholone engaging in a structure with the estrogen receptor itself. Since it has an A-ring similar to that of estradiol (the prime estrogen) so this would be the most logical explanation. Since progesterone acts as an estrogen agonist, it would require circulating estrogen to negotiate such levels of water build-up as oxymetholone causes, so it seemed like a far-fetched idea to begin with.

Bromocriptine inhibits prolactin, but not progesterone. The growth hormone inhibiting effects are only present in acromegalic patients and actually increases GH in normal users.

The endocrine profile of bromocriptine: its application in endocrine diseases.

Lancranjan I.

Bromocriptine, a potent agonist at Dz receptors, was developed as a therapeutic agent for inhibiting prolactin (PRL) secretion in patients with hyperprolactinemia. Besides, its PRL-suppressive effect and a short-lasting growth hormone (GH)-releasing effect in normal volunteers, bromocriptine has no other endocrine effects in healthy subjects. On the other hand, bromocriptine lowers GH secretion in acromegalic patients and ACTH secretion in some patients with Cushing's disease or Nelson's syndrome. The paper reviews the endocrine actions of bromocriptine in man, in normal and pathological conditions, the bromocriptine's mechanism of action and its clinical applications in endocrinology.

B32....

 

[needsize]

good info, thanks.

if controlling estrogen is the ticket, I would how arimidex would work

 

[b1ewsw32]

good info, thanks.

if controlling estrogen is the ticket, I would how arimidex would work

Arimidex wouldn't be useful here as Anadrol doesn't aromatize.
You need tamoxifen 20-40mgs/day for drols and 50mgs eod of stanozolol to control progestogenic effects of Deca-D.
IMO that's what has worked for me in the past.

 

[pharmguy]

Maybe you should nix the drol and use dbol instead?

 

[alltraps]

just get the cabergoline. i'll split on it with you. the brits are back from vacation so we can have it in a few days.

 

[needsize]

just get the cabergoline. i'll split on it with you. the brits are back from vacation so we can have it in a few days.

not a bad idea, I guess I'm in

pharmguy, I've used dbol on every cycle except for one, so I really want to see how i repond to drol under these conditions. I also have 100 green giants sitting here staring at me