Well I've gone as high as 750mgs of Test without running an anti-e along with it. Actually I've never run an anti-e during a cycle. I plan to give Arimidex a try on my next test cycle though. This - "You must run Arimidex" thing is fairly new, go back 2 - 3 years ago and most people wouldn't know what you were talking about. You either took Nolvadex at a regular dose along with the cycle, or you had it close by if you had a problem.