chronic hypertension from AS???

[Keep it beefy]

can anyone enlighten me on the chronic hypertensive effects of AS. i know blood pressure rises while on cycle, but i've also heard that after prolonged used, they can cause hardening of blood vessels. that is where the chronic part comes in. anyone have any insight into any of this? thanks.

 

[Keep it beefy]

my blood pressure is 140's/70's on cycle, and much less off cycle. i have some ace inhibitors on hand, but i don't want to fuck with them when i don't fully understand the ramifications just yet. i just read (in the archives here)that they are good for a high diastolic, but not so good for a high sistolic. but rather, diuretics are good for high sistolic's. thing is, i imagine you lose some anabolism by draining water from your body. i'm on dbol/primo. what do you guys think i should do?

 

[Keep it beefy]

here's a tid bit from the following link, in case anyone cares...

http://www.clinical-cardiology.org/supplements/CC23S4/CC23S4.pitt.html

CHF = congestive heart failure
MI = miocardial infarction or heart attack
CV = cardio vascular
LV = left ventricular

Hypertension

In patients with hypertension, ACE inhibitors have been judged as effective as beta blockers and thiazide diuretics in reducing blood pressure and slightly less effective than calcium antagonists. There is substantial, but not conclusive, evidence that ACE inhibitors are more effective than any other standard antihypertensive drug class in reversing hypertensive LV hypertrophy,4 a forecaster of CHF, MI, and other CV events.7 Whether such reversal prevents CV events is uncertain.4

The ACE inhibitors have been shown to have beneficial effects in hypertensive patients with coexistent diabetes, partly because they reduce proteinuria and slow the progression of diabetic nephropathy in patients with type 1 diabetes and appear to act similarly in type 2 diabetes.1 Randomized clinical comparisons of an ACE inhibitor and a calcium-channel blocker in both the Fosinopril versus Amlodipine Cardiovascular Events Randomized Trial (FACET) and Appropriate Blood Pressure Control in Diabetes (ABCD) trial (enalapril vs. nisoldipine) credited ACE inhibition for significant relative reductions in CV events of definite or probable ischemic origin in patients with hypertension and type 2 diabetes. Since ACE inhibition was either similar to (ABCD) or less effective (FACET) than calcium blockade in reducing blood pressure, its superior CV protection has been speculatively attributed to more direct anti-ischemic effects.1 Further prospective comparison of ACE inhibition to calcium-channel blocking agents and the combination of ACE inhibitor and a calcium-channel blocking agent will, however, be required before any final conclusions as to the relative effectiveness of these agents can be determined.