Check out this AE half-life profile of various drugs

[The Iron Game]

IG, I think Andy is correct

ya still think so

 

[The Iron Game]

Did I state that?

http://209.11.101.244/forum/newreply.php?s=&action=newreply&postid=534991

30mg T-prop 2 days
60mg phenylP 3 days
60 isocar. 6 days
100mg dec 10 days.

Andy

I think you did Sir

 

[The Iron Game]

Iron Game,
are you sure that half life of drugs depend on the sex? Yes, Arimidex is a drug for women, but it shouldn't have a different half life in men(IMHO) 40-50 hours half life is mentioned in that little leaflet of a original Zeneca Arimidex.

Think about what arimidex does and what it is used for and how it works and then you will have answered your own question.

Yes it does matter

 

[The Iron Game]

btw Andy you still believe ALL esterified steroids peak within 24 hours?

 

[The Iron Game]

posts fall of the bottom of the page so quickly nowadays

 

[panerai]

quote:
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Originally posted by panerai

IG, I think Andy is correct
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ya still think so

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Well, I don't know...like I said, we have very incolclusive data from different studies.
Half life of Decanoate is 6.5hrs, by one, and 10hrs, by another, that's a big difference! Most likely, that PP's half life falls between 3 and 6 days, which is very close to Enanthate(5days)
As for peaking in 24 hrs, it looks like at least most if not of them do peak in first 24 hrs. Don't forget that it depends on many factors, like injection volume, injection site, injection technique, etc..so there's no exact number for those things.

 

[Nimrod25]

Just when I though this board lacked posts of substance, I get hit with this. Well done gentlemen.

 

[panerai]

Ooops, my bad, I made mistake.
That's abstract from Nandrolone study:
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Pharmacodynamic analysis. Plasma testosterone concentrations were most rapidly and completely suppressed within the first week after injections of the phenylpropionate ester (fig. 3; tables 2 and 6), but this suppression was sustained for the shortest time. The duration of suppression was significantly longest after the gluteal 1-ml injection. Plasma testosterone concentrations returned to base line by day 13 after the phenylpropionate ester but required >20 days to return to base-line levels after the decanoate ester.

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As you can see, they are not talking about nandrolones concentration in plasma, but about the duration of testosteron suppression which is not the same.
So, now knowing that Decanoate's half life is 6.5 days and it has duration of suppression of 20 days, and PP's duration of suppression, with the same dosage is 13 days, we can easily find calculate half life of PP.
half life(PP)= 13x6.5/20=4.225 days
So, half life of Phenylpropionate is approx. 4 days.

 

[Andy13]

btw Andy you still believe ALL esterified steroids peak within 24 hours?

I believe blood concentrations get very high after 24hrs.. And after 5 days, with a long ester such as deconate, they might get a little higher.. But the point of me saying that was to let guys know that all steroids peak EARLY. Some guys erroneously think that decaonate goes for a week or whatever and then all the sudden BAM hits max blood concnetration... These guys think an injection plot looks like a bell curve, when, it actuality, it looks more like a downward ski sloap.

As for the esters and their half lives-- Beats me. You can compare acetate, propionate, enanthate, and deconate to each other since they are all straight, saturated chains.. but you cannot compare esters such as: phenyl propionate, cypionate to anything. I would guess phenyl propionate to have a half life somewhere between propionate and cypionate. The cypionate ester is a saturated ring, the PP ester is an aromatic (non saturated) ring. Generally, the more unsaturated a lipid is, the less lipophilic. But I don't think it would be FASTER than propionate.. But somewhere between the two..

I have heard SOOOO much conflicting evidence when it comes to half lives that, in my graphs, I just try to take the generally accepted (average) half life from what differenct sources say.

Andy

 

[Audio8]

andy,
that's a very good point that many don't realize..blood levels peak fast and fade fast..thus, the chart will look like a parabola with downward concavity UNTIL MAX CONCENTRATION...then concavity will reverse as blood levels go down (if this makes noe sense, i can draw a rough picture up for you guys)

bump for the new school crew...