As mentioned above, you don't have to do 5x5 as a cookie-cutter. You can still get a lot out of the "take home" principles, which is the goal of running the 5x5 program anyway. One of those principles, as CS mentioned, is higher-frequency and less volume. So, adapting that to your one-bodypart/wk. routine, take the number of sets you're used to doing for a particular bodypart, and just spread it out over 2-3 sessions/wk. So, rather than 20 sets for chest, do 5 sets for chest (rep range doesn't matter) on Monday, 5 more sets on Wed., and 5 more sets on Friday. The rep range is irrelevant, IMO. diff't ranges for diff't goals. But spreading out the volume will be a nice change and works well for many people. BB'rs are the only people still doing that kind of "massed" training once a week . . .