Can I drink oil based winny? :)

[nicecannons]

oil based winny DOES exist and quite a few UG labs carry it now......it halflife is NO different from water based winny in that the water or oil have nothing to do with release time....as in testosterone, the esther determines the release time, not the oil its in.....

now, im not sure as to rather or not you can drink this shit....i would assume so. and teh people i know who have inhjected this oil based winny said it was painful as hell also

ive used apex oil based and it was painfull but so is water based for me.had good results on the oil with less injections.works out cheaper too

 

[deezknuckles]

I'm going to have to respectfully disagree.

The vehicle in which a drug is dissolved has alot to do with the absorption of that drug across biological membranes and into the circulation. When a drug is administered intramuscularly, it goes through the stepwise process of absorption, distribution throughout body, metabolism, and excretion (as metabolites or unchanged drug). The kinetics of absorption are influenced by the equilibrium between the drug in its vehicle and that which traverses a biological membrane to be distributed. The solubility of the drug in its particular vehicle affects that rate and can therefore influence the entite kinetic process of drug input/output and therefore pharmacological effect.

With oral ingestion, there is the additional step of the drug being "liberated" from the dosage form or vehicle in the stomach, then going to the hepatic portal vein to be processed by the liver, and then reaching the general circulation. I have no proof but I speculate that alot of winsrtol would remain dissolved in the oil in the stomach, only to pass through and get crapped out without being absorbed into the hepatic portal vein and having a chance to get into the circulation.

I could be wrong, but please, for my sanity, just inject the fukkin winny :>) !!

 

[mlong23]

I'm going to have to respectfully disagree.

The vehicle in which a drug is dissolved has alot to do with the absorption of that drug across biological membranes and into the circulation. When a drug is administered intramuscularly, it goes through the stepwise process of absorption, distribution throughout body, metabolism, and excretion (as metabolites or unchanged drug). The kinetics of absorption are influenced by the equilibrium between the drug in its vehicle and that which traverses a biological membrane to be distributed. The solubility of the drug in its particular vehicle affects that rate and can therefore influence the entite kinetic process of drug input/output and therefore pharmacological effect.

With oral ingestion, there is the additional step of the drug being "liberated" from the dosage form or vehicle in the stomach, then going to the hepatic portal vein to be processed by the liver, and then reaching the general circulation. I have no proof but I speculate that alot of winsrtol would remain dissolved in the oil in the stomach, only to pass through and get crapped out without being absorbed into the hepatic portal vein and having a chance to get into the circulation.

I could be wrong, but please, for my sanity, just inject the fukkin winny :>) !!

Agree.

 

[drrman]

I'm going to have to respectfully disagree.

The vehicle in which a drug is dissolved has alot to do with the absorption of that drug across biological membranes and into the circulation. When a drug is administered intramuscularly, it goes through the stepwise process of absorption, distribution throughout body, metabolism, and excretion (as metabolites or unchanged drug). The kinetics of absorption are influenced by the equilibrium between the drug in its vehicle and that which traverses a biological membrane to be distributed. The solubility of the drug in its particular vehicle affects that rate and can therefore influence the entite kinetic process of drug input/output and therefore pharmacological effect.

With oral ingestion, there is the additional step of the drug being "liberated" from the dosage form or vehicle in the stomach, then going to the hepatic portal vein to be processed by the liver, and then reaching the general circulation. I have no proof but I speculate that alot of winsrtol would remain dissolved in the oil in the stomach, only to pass through and get crapped out without being absorbed into the hepatic portal vein and having a chance to get into the circulation.

I could be wrong, but please, for my sanity, just inject the fukkin winny :>) !!

good points...

 

[cubuff27]

Seems like too much to worry about...just inject it or buy the oral next time.