Can anybody explain this to me?

[Robert Jan]

this is a description of the things that happen caused by weighttraining. all good, but i dont see what theyre talking about in the genetic response paragraph.

When type 2 fibers are exhausted like this, in short, the following process takes place:

Neural Response
The first measurable effect is an increase in the neural drive stimulating muscle contraction. Within just a few days, an untrained individual can achieve measurable strength gains resulting from "learning" to use the muscle. This is described in more detail earlier in this document.

??????????????
Genetic Response
As the muscle continues to receive increased demands, the synthetic machinery is upregulated. Although all the steps are not yet clear, this upregulation appears to begin with the ubiquitous second messenger system (including phospholipases, protein kinase C, tyrosine kinase, and others). These, in turn, activate the family of immediate-early genes, including c-fos, c-jun and myc. These genes appear to dictate the contractile protein gene response.
??????????

Protein Synthesis
Finally, the message filters down to alter the pattern of protein expression. It can take as long as two months for actual hypertrophy to begin. The additional contractile proteins appear to be incorporated into existing myofibrils (the chains of sarcomeres within a muscle cell). There appears to be some limit to how large a myofibril can become. At some point, they split. These events appear to occur within each muscle fiber. That is, hypertrophy results primarily from the growth of each muscle cell, rather than an increase in the number of cells.

 

[WalkingBeast]

Complete ubiquitous phospholipastic tyrosinel immediate-early gene response bullshit IMO.

 

[Robert Jan]

are you saying it is simply not true?

 

[WalkingBeast]

Im just saying, I dont think things of this nature are so clear. Black and white. People can define things they see to an extent, but when you get to the molecular level of genes, I think things start to become very open for interpretation. All different types. Im not a scientist, but I dont need to be to make good gains in strength and size.

 

[d3track]

Im just saying, I dont think things of this nature are so clear. Black and white. People can define things they see to an extent, but when you get to the molecular level of genes, I think things start to become very open for interpretation. All different types. Im not a scientist, but I dont need to be to make good gains in strength and size.

excellent
you don't have to over-examine everything
think Michael Johnson sat there in the library trying to figure out the chemical reason he ran fast?
He got his ass to the track and kept working on form and trying to go faster

 

[Tom Treutlein]

Very true, but some things have been proven, as in the ideal way to increase your size (i.e., HST) by means of proper training and diet. I'm not 100% convinced by that, however. I do believe there may be something more we're missing, because people like WB can go in and destroy themselves and make massive gains, as much as someone who goes in more often and uses less volume and/or intensity. Supposedly WB is just overworking himself and his CNS is getting pounded more than need be for his goals, but I don't know if I buy into that entirely.

 

[WalkingBeast]

ThanX guys!! Yea I think there are ALOT of huge gaps in many of the theories I hear about lifting and dieting. I hope to give everyone here another view that I havent seen presented in the past. Im nocturnal most of the time, my diet isnt too clean at all, and my training methods go against everything Ive ever read. Its just the way everything developed over time. Ive always read information on lifting and diet, but most importantly I wanted to carve my own path, find what worked for me. It seems there are way too many cookie cutter routines out there, and I dont like the idea of having a complete routine pre written. If Im feeling stronger on a certain day, I would rather go for a PR rather then stick to what a routine says. I stuck to a written routine when I started, and for some years too, but eventually I started to train more instinctually. I like it much better, because Im able to continuously customize my routine, and manipulate weights and reps to set new PR's. I think it takes some time to learn what works best for you. The main thing I was trying to say is that I think absolute truth is thrown around way too much. I dont believe there is any real way to know absolute truth. Our perceptions may only take us so far. We can form strong theories but this does not make them truth. Everything I state on this site is only my opinion, it cannot be absolute truth. Truth has to be known. A theory is just that.

 

[casualbb]

Protein Synthesis
It can take as long as two months for actual hypertrophy to begin.

That one major claim is majorly wrong.

Hypertrophy CAN and DOES begin immediately upon embarking on a new program. Get the diet in line and a new lifter will explode with growth. It doesn't just spontaneously decided to kick in after two months.

 

[Lord_Suston]

this is a description of the things that happen caused by weighttraining. all good, but i dont see what theyre talking about in the genetic response paragraph.

When type 2 fibers are exhausted like this, in short, the following process takes place:

Neural Response
The first measurable effect is an increase in the neural drive stimulating muscle contraction. Within just a few days, an untrained individual can achieve measurable strength gains resulting from "learning" to use the muscle. This is described in more detail earlier in this document.
The neural adaption is usually referred as coordination. Basically doing a different activity make one's CNS work really hard since muscle recruitment patterns are not use to the type of excercises. A marathon runner can run well, but have him sprint and he will not be as proficient as he could be because his CNS is use to running at a certain pace and recruiting muscle in a certain time and loading parameters.

??????????????
Genetic Response
As the muscle continues to receive increased demands, the synthetic machinery is upregulated. Although all the steps are not yet clear, this upregulation appears to begin with the ubiquitous second messenger system (including phospholipases, protein kinase C, tyrosine kinase, and others). These, in turn, activate the family of immediate-early genes, including c-fos, c-jun and myc. These genes appear to dictate the contractile protein gene response.
??????????
I think this refers to one's abilitiy to actually heal from trauma inducing excercises, most likely in the cytoplacm of the cell. Most likely a factor in healing the cells used but not building new ones

Protein Synthesis
Finally, the message filters down to alter the pattern of protein expression. It can take as long as two months for actual hypertrophy to begin. The additional contractile proteins appear to be incorporated into existing myofibrils (the chains of sarcomeres within a muscle cell). There appears to be some limit to how large a myofibril can become. At some point, they split. These events appear to occur within each muscle fiber. That is, hypertrophy results primarily from the growth of each muscle cell, rather than an increase in the number of cells.

In humans cells get bigger in most cases rather than split. So if you had 100 cells in your bicept and they are 15" at 20" you will still have 100cells they will just be bigger.You just have more contractile protein in the cell. Growth being delayed for two months can happen with hardgainers and those who need to adapt the internal organells for weight loaded excercises.