Prolactin is used in immune system signaling. In other words, it's a hormone you're immune systems uses to communicate with its various components. While Dostinex appears to be site specific, to the pituitary, I'd still be concerned about this potential interaction.
For people with severely suppressed PRL levels there are sides. Those include runny nose, headaches, fatigue, and occasionally nausea.
To the first question: it works very quickly. At just .25mg (not .5 and not 1) 2x EW I had a PRL level of 1 in just two weeks. From what I could tell the anti-refractory effect starts working within the first week.
For people with severely suppressede PRL levels there are sides. Those include runny nose, headaches, fatigue, and occasionally nasuea.