Bridging cycles with Primobolin

[yomama]

I'd still like to know why people bridge if they ever have intentions of comming off.

Someone enlighten me

Really

It's an addiction. Cycles longer than 4months suck, for some reason my tendons start to bother me, my fuckin knee mostly. I got it scanned a year ago and it showed minor tears, since then it healed but now it came back. So I have no choice but to stop cycle and have it recover.

 

[Jenetic]

It's an addiction.

At least your honest about it.

Jenetic

 

[bicepts101]

well i think this is the same idea of proviron.....supposidly proviron will keep u suppressed if already suppressed...but when taken when test levels are normal it doesnt suppress....maybe its the same with primo..idk...maybe thats why primo is so easy to recover from??....im not scientist and i dont use these methods but im throwing things out there

 

[bicepts101]

heres a study on proviron..still lookin on the primo:
Oral synthetic 17-a alkylated androgens such as methyltestosterone (96), fluoxymesterone (97), methandienone (98) and danazol (99, 100) suppress spermatogenesis but azoospermia is rarely achieved and the inherent hepatotoxicity of the 17-a alkyl substitutent (101) renders them unsuitable for long-term use. Athletes self-administering supratherapeutic doses of androgens also exhibit suppression of spermatogenesis (98, 102). Synthetic androgens lacking the 17-a alkyl substituent have been little studied although injectable nandrolone esters produce azoospermia in 88% of European men (103, 104) whereas oral mesterolone is ineffective (105). On the other hand, nandrolone hexyloxyphenylpropionate alone was unable to maintain spermatogenic suppression induced by a GnRH antagonist (106) in a prototype hybrid regime (where induction and maintenance treatment differ) whereas testosterone appears more promising (107). A 7-methyl derivative of nandrolone (MENT), which is partly aromatisable but resistant to 5α reductive amplification of androgenic potency, has been studied as a non-oral androgen for hormonal male contraceptive regimens (108). While it is prostate-sparing (109), dose titration to achieve essential androgen replacement at each relevant tissue is more complex than for testosterone and may be difficult to achieve (110). More potent, synthetic androgens lacking 17-a alkyl groups (111, 112) remain to be fully evaluated.

97. Jones TM, Fang VS, Landau RL, Rosenfield RL 1977 The effects of fluoxymesterone administration on testicular function. J Clin Endocrinol Metab 44:121-129

98. Holma PK 1977 Effects of an anabolic steroid (metandienone) on spermatogenesis. Contraception 15:151-162

99. Skoglund RD, Paulsen CA 1973 Danazol-testosterone combination: a potentially effective means for reversible male contraception. a preliminary report. Contraception 7:357-365

100. Sherins RJ, Gandy HM, Thorslund TW, Paulsen CA 1971 Pituitary and testicular function studies. I. Experience with a new gonadal inhibitor, 17a-pregn-4-en-20-yno-(2,3-d) isoxazol-17-ol (Danazol). J Clin Endocrinol Metab 32:522-531

101. Ishak KG, Zimmerman HJ 1987 Hepatotoxic effects of the anabolic-androgenic steroids. Semin Liver Dis 7:230-236

102. Knuth UA, Maniera H, Nieschlag E 1989 Anabolic steroids and semen parameters in bodybuilders. Fertil Steril 52:1041-1047

103. Knuth UA, Behre H, Belkien L, Bents H, Nieschlag E 1985 Clinical trial of 19-nortestosterone hexoxyphenylpropionate (Anadur) for male fertility regulation. Fertil Steril 44:814-821

104. Schurmeyer T, Knuth UA, Belkein L, Nieschlag E 1984 Reversible azoospermia induced by the anabolic steroid 19-nortestosterone. Lancet 1:417-420

105. Schellen TNCM, Beek JMJHA 1972 The influence of high doses of mesterolone on the spermiogram. Fertil Steril 23:712-714

106. Behre HM, Kliesch S, Lemcke B, von Eckardstein S, Nieschlag E 2001 Suppression of spermatogenesis to azoospermia by combined administration of GnRH antagonist and 19-nortestosterone cannot be maintained by this non-aromatizable androgen alone. Hum Reprod 16:2570-7

107. Swerdloff RS, Bagatell CJ, Wang C, Anawalt BD, Berman N, Steiner B, Bremner WJ 1998 Suppression of spermatogenesis in man induced by Nal-Glu gonadotropin releasing hormone antagonist and testosterone enanthate (TE) in maintained by TE alone. J Clin Endocrinol Metab 83:3527-33

108. Sundaram K, Kumar N 2000 7alpha-methyl-19-nortestosterone (MENT): the optimal androgen for male contraception and replacement therapy. Int J Androl 23 Suppl 2:13-5

109. Cummings DE, Kumar N, Bardin CW, Sundaram K, Bremner WJ 1998 Prostate-sparing effects in primates of the potent androgen 7alpha-methyl-19-nortestosterone: a potential alternative to testosterone for androgen replacement and male contraception. Journal of Clinical Endocrinology & Metabolism 83:4212-9

110. Anderson RA, Wallace AM, Sattar N, Kumar N, Sundaram K 2003 Evidence for tissue selectivity of the synthetic androgen 7 alpha-methyl-19-nortestosterone in hypogonadal men. J Clin Endocrinol Metab 88:2784-93

111. Avery MA, Tanabe M, Crowe DF, Detre G, Peters RH, Chong WKM 1990 Synthesis and testing of 17ab-hydroxy-7a methyl-D-homoestra-4,16-dien-3-one: a highly potent orally active androgen. Steroids 55:59-64

112. Grootenhuis AJ, de Gooyer ME, Louw J, Bursi R, Leysen D 2004 Synthesis and pharmacological profiling of new orally active steroidal androgens. In: Nieschlag E, Behre HM (eds) Testosterone: Action, Deficiency and Substitution, 3rd ed. Springer-Verlag, Berlin, pp 665-84

 

[yomama]

heres a study on proviron..still lookin on the primo:
Oral synthetic 17-a alkylated androgens such as methyltestosterone (96), fluoxymesterone (97), methandienone (98) and danazol (99, 100) suppress spermatogenesis but azoospermia is rarely achieved and the inherent hepatotoxicity of the 17-a alkyl substitutent (101) renders them unsuitable for long-term use. Athletes self-administering supratherapeutic doses of androgens also exhibit suppression of spermatogenesis (98, 102). Synthetic androgens lacking the 17-a alkyl substituent have been little studied although injectable nandrolone esters produce azoospermia in 88% of European men (103, 104) whereas oral mesterolone is ineffective (105). On the other hand, nandrolone hexyloxyphenylpropionate alone was unable to maintain spermatogenic suppression induced by a GnRH antagonist (106) in a prototype hybrid regime (where induction and maintenance treatment differ) whereas testosterone appears more promising (107). A 7-methyl derivative of nandrolone (MENT), which is partly aromatisable but resistant to 5α reductive amplification of androgenic potency, has been studied as a non-oral androgen for hormonal male contraceptive regimens (108). While it is prostate-sparing (109), dose titration to achieve essential androgen replacement at each relevant tissue is more complex than for testosterone and may be difficult to achieve (110). More potent, synthetic androgens lacking 17-a alkyl groups (111, 112) remain to be fully evaluated.

I dont get what the point of this study is.

 

[bicepts101]

it says it didnt suppress

 

[bicepts101]

ok heres something on primo...it has no reference so im sure you wont accept it:

For example, in one study more than half of the patients receiving only 30-45 mg noted a suppression of gonadotropin levels of 15% to 65% a. This is a dose far less than most bodybuilders would use, and no doubt increasing it would only lead to worse suppression. One would therefore still need a testosterone stimulating drug like HCG or Clomid®/Nolvadex® when concluding a low-dose Primobolan® cycle, unless a deliberately small dose were being used.

basically this say what ive always heard...it will be easier to recover from cause it doesnt shut you down too hard

 

[bicepts101]

heres some info on primo if anyones interested:

This section refers to the oral Primobolan® preparation, which contains the drug methenolone acetate. It is very similar in action to the injectable Primobolan® Depot (methenolone enanthate), but obviously here the drug is designed for oral administration. At one time Schering was in fact also manufacturing an injectable methenolone acetate (Primobolan® acetate, out of manufacture since 1993), which proved to be very useful for pre-contest cutting purposes. This steroid is now gravely missed, as it was once a favorite among European competitors. Although we still have the acetate in oral form, it is a close, but not equal substitute (injection is a much more efficient form of delivery for this steroid).

Methenolone regardless of the ester is a very mild anabolic steroid. The androgenic activity of this compound is considerably low, as are its anabolic properties. One should not expect to achieve great gains in muscle mass with this drug. Instead, Primobolan® is utilized when the athlete has a specific need for a mild anabolic agent, most notably in cutting phases of training. It is also a drug of choice when side effects are a concern. A welcome factor is that Primobolan® is not c17 alpha alkylated as most oral steroid are. Due to the absence of such an alteration, this compound is one of the few commercially produced oral steroids that is not notably stressful to the liver. While liver enzymes values have been affected by this drug in some rare instances, actual damage due to use of this substance is not a documented problem. Unfortunately the 1 alkylation and 17-beta esterification of Primobolan® do not protect the compound very well during first pass however, so much of your initial dose will not make circulation. This is obviously why we need such high daily dose with the oral version of Primobolan®.

Primobolan® will also not aromatize, so estrogen related side effects are of no concern. This is very useful when leading up to a bodybuilding contest, as subcutaneous water retention (due to estrogen) can seriously lessen the look of hardness and definition to the muscles. Non-aromatizing steroids are therefore indispensable to the competitor, helping to bring about a tight, solid build the weeks leading up to a show. And of course without excess estrogen there is little chance of the athlete developing gynecomastia. Likewise there should never be a need for anti-estrogen use with this steroid. Primobolan® is also said to have a low impact on endogenous testosterone production. Although this may well be true in small clinical doses, it will not hold true for the bodybuilder. For example, in one study more than half of the patients receiving only 30-45 mg noted a suppression of gonadotropin levels of 15% to 65% a. This is a dose far less than most bodybuilders would use, and no doubt increasing it would only lead to worse suppression. One would therefore still need a testosterone stimulating drug like HCG or Clomid®/Nolvadex® when concluding a low-dose Primobolan® cycle, unless a deliberately small dose were being used.

It is also important to note that although the androgenic component of Primobolan® is low, side effects are still possible. One may therefore notice oily skin, acne and facial/body hair growth during treatment. Men with a predisposition for hair loss may also find it exacerbates this condition, and wish to avoid this item (nandrolone injectables are a much better choice). While always possible, side effects rarely reach a point where they interfere with the progress of cycle. Primobolan® is clearly one of the milder and safer oral steroids in production. Female athletes, older or more sensitive individuals and steroid beginners will no doubt find this a comfortable steroid to experiment with.

The dosage for men is somewhere in the range of 75-150mg daily. This can obviously be tedious (and costly) if one can only obtain the 5mg tablets from Mexico and S. America. A mild anabolic such as Primobolan® is often used in conjunction with other steroids for optimal effect, so some users find a slightly lower dose effective when stacking. During a dieting or cutting phase, thought to be its primary application, a non-aromatizing androgen like Halotestin® or trenbolone can be added for example. Such combinations would enhance the physique without water retention, and help bring out a harder and more defined look of muscularity. Non-aromatizing androgen/anabolic stacks like this are in fact very popular among competing bodybuilders. This compound is also occasionally used with more potent androgens during bulking phases of training. The addition of testosterone, Dianabol or Anadrol 50® would prove effective for instance, although the gains are likely to be accompanied by some level of smoothness due to the added estrogenic component.

Among women, Primobolan® is one of the most popular steroids in use. At a dosage of 50-75mg daily, virilization symptoms are extremely uncommon. One would of course not expect a tremendous amount of muscle mass with this drug, and instead should expect a slow and steady (quality) increase. Some women choose to further add-in other anabolics such as Winstrol® or oxandrolone, in an effort to increase the muscle building effectiveness of a cycle. While both of these compounds are quite tolerable to women, one must be sure not to use too high an accumulated dosage. Troublesome androgenic side effects are always a possibility with steroid use, even with very mild substances. Taken at too high a dosage, these weak anabolics can become a formidable danger to femininity. It would therefore be the best advice not to use the normal dosage range of both, but instead start with a much lower dosage of each steroid to compensate for the other. On the black market Primobolan® orals are popular, but still much less commonly found than the injectable. This is due to the higher cost effectiveness of the injectable, which uses the same active compound but with 100% bioavailability due to the form of administration.

 

[TheAssholeFomerlyKnownAsDBBT]

Not a big fan of bridging. It's just another way of saying that you are still on, but
at a very low level. Unless you compete and bodybuilding puts food on your table, I don't recommend bridging, regardless of the compound.

ditto

 

[Anthony Starks]

Sorry to bring back a post over two weeks old, but I was wondering if everyone still thinks Primo, or any other AS for that matter, will not suppress your HTPA.