You're going to get a lot of varrying view points on this one. Anti-D's did nothing for me except make me a lazy, fat accumulating, still depressed zombie. In fact I felt worse on them that off. As much as anyone in our shoes hates to admit it you have to make an effort to fight this with your own brain power. It's not easy, but finding little things that relax you and take your mind off of shit is the best start. I like to kick back every night and watch some sporting event. Basball in the summer. Football and basketball in the fall and my personal favorite, hockey in the winter. Sounds bland, but that's the idea. Find small, easy things to do that aren't a source of stress or fuel for pessimism. You have to put your mind into this. You can't "think" depression away, but you can learn to controll it. Learn what triggers your uneasy moods and avoid those thoughts or activities. Make an effort to change your life. I used to be very socially isolated(social anxiety disorder). I relied on drugs in hopes that they would magically change my personality. They did jack shit, so I took it upon myself to talk to anyone anywhere. Developing social skills took a lot of presure off of myself. That was one step forward and it wasn't a result of medications. It was because I too it upon myself to change my situation. You need to find out what it is that bothers you and then you need to find out how to take that cue and act on it.