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Best fat burner that doesn't ruin cardio?

Re: Best "fat burner" that doesn't ruin endurance/cardio in any way?

KOArtist said:
I was considering dropping a weight class, and considering the help of t3 and/or clen to do it. Do either of these two compounds ruin your cardio and/or training capacity? I was afraid to try clen because I hear about how it "scars your heart" and that surely doesn't sound like a good thing for my cardio nor my lifespan. Does T3 have any "negative cardio effects"?
Good Question Bro.
 
As far as the clen thing, I've read in a few different places that it causes heart cell death. It seems like there is always a journal reference in MD to this effect. I'm not sure what mechanism of clen kills heart cells, maybe just overstimulation.
 
i used clen and it made ME feel identical as ephedra. id get headaches and the shakes, and the heart is pumping like crazy, but the energy levels and fat loss have always been great.
 
JThompson24 said:
bump on the chest scarring, any info


J Appl Physiol. 2005 Apr;98(4):1379-86. Epub 2004 Dec 10. Related Articles, Links


beta2-Adrenergic receptor stimulation in vivo induces apoptosis in the rat heart and soleus muscle.

Burniston JG, Tan LB, Goldspink DF.

Research Institute for Sports and Exercise Sciences, Liverpool John Moores Univ., Webster St., Liverpool, L3 2ET, United Kingdom. [email protected]

High doses of the beta2-adrenergic receptor (AR) agonist clenbuterol can induce necrotic myocyte death in the heart and slow-twitch skeletal muscle of the rat. However, it is not known whether this agent can also induce myocyte apoptosis and whether this would occur at a lower dose than previously reported for myocyte necrosis. Male Wistar rats were given single subcutaneous injections of clenbuterol. Immunohistochemistry was used to detect myocyte-specific apoptosis (detected on cryosections via a caspase 3 antibody and confirmed with annexin V, single-strand DNA labeling, and terminal deoxynucleotidyl transferase-mediated dUTP nick-end labeling). Myocyte apoptosis was first detected at 2 h and peaked 4 h after clenbuterol administration. The lowest dose of clenbuterol to induce cardiomyocyte apoptosis was 1 microg/kg, with peak apoptosis (0.35 +/- 0.05%; P < 0.05) occurring in response to 5 mg/kg. In the soleus, peak apoptosis (5.8 +/- 2%; P < 0.05) was induced by the lower dose of 10 microg/kg. Cardiomyocyte apoptosis was detected throughout the ventricles, atria, and papillary muscles. However, this damage was most abundant in the left ventricular subendocardium at a point 1.6 mm, that is, approximately one-quarter of the way, from the apex toward the base. beta-AR antagonism (involving propranolol, bisoprolol, or ICI 118551) or reserpine was used to show that clenbuterol-induced myocardial apoptosis was mediated through neuromodulation of the sympathetic system and the cardiomyocyte beta1-AR, whereas in the soleus direct stimulation of the myocyte beta2-AR was involved. These data show that, when administered in vivo, beta2-AR stimulation by clenbuterol is detrimental to cardiac and skeletal muscles even at low doses, by inducing apoptosis through beta1- and beta2-AR, respectively.
 
Jenetic said:
I wouldn't go as far as to say there is no substitute. Are we forgetting the Levorex and Yohimburn ES combination? Levorex by itself is a great weight loss aid. The high quality concentrations of green tea extract (98%,50% eGCG, 180 mgs/2 capsules) contained in Levorex provides excellent thermogenic and nutrient partitioning effects. The nutrient partitioning effects are much like those of Glucorell (RLA). Therefore, there is absolutely no reason to cut carbohydrates drastically, especially when combining both anaerobic and aerobic exercise togehter in a training program. In addition, the nootropics contained in Levorex are a welcomed bonus. Yohimburn ES by itself is an excellent, but often overlooked, preworkout aid. Levorex + Yohiburn = Quality Results.

Jenetic

Totally agree.

I think Levorex is very under-rated as it does not contain per-se stimulants,
I always cut with 16-20 Levorexes a day, really like the ingredient combination.
 
junk said:
Totally agree.

I think Levorex is very under-rated as it does not contain per-se stimulants,
I always cut with 16-20 Levorexes a day, really like the ingredient combination.

JUNK.. the cuttin king of all time.
people what this mean says about cuttin is the final word!!!
 
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