Article in FLEX: aspirin/common pain relievers supress muscle protein synthesis

[athlete03]

Scary Uncle Martin.

 

[monkeyballs]

While both ibuprofen and acetaminophen are fever reducers only ibuprofen is a antiinflamatory, as is asprin. Acetaminophen works by blocking the pathway by which pain signals are sent to the brain. Please anyone correct me if I'm wrong.

Not so sure that this is correct. I thought that any fever-reducer would by nature have to also be an anti-inflamatory.

 

[Little Rage]

Acetaminophen is a medication (analgesic) that is available without a doctor’s prescription (over-the-counter). It is commonly used for mild to moderate pain such as headache, aches and pain associated with colds and influenza, and arthritis pain. It is also used to reduce mild to moderate fever, but it does not have anti-inflammatory properties (it is not used to reduce swelling). It is available in tablets, syrup (suspension), and suppositories. It should never be taken with alcohol. People with liver disease such as Hepatitis should not take acetaminophen. Although this drug is considered very safe when used as directed, extreme care should be taken, especially with children, since it can cause liver damage in high dosages. Side effects are rare but it may cause a rash and/or itching.

 

[monkeyballs]

Tylenol Suppositories...wow. Learn something new every day.

 

[serge]

well just got done reading this article (FLEX: June 2002) and all i can say is "fuck me."



Just wanted to hear some of ur comments or thoughts about this if u've read it.

it interferece with prostaglandin synthesis, so does IB

 

[hard as rocks]

well doesnt that go against are use of ephedrine, caffeine ans aspirin.
i know most bodybuilders take eca before the gym just for the boost.
do you reall think this is affecting protein synthesis to a high degree.i highly doubt it, considering the amount of protein we consume daily.

 

[projection]

this is great seems like everything I do or take suppress testosterone or interferes with protein synthesis.

 

[HighIntensity]

thanks I just tossed my advil

 

[Hugh Gellatts]

had to bump this back from the dead.

I feel the pain off all that have stopped taking advil or other anti-inflammatories for the past two weeks. I have been in intimate communication with my right elbow, and it is telling me it does not like me or the fact that I like to work triceps very heavy

hoping that some durabolin will shut the bastard up.

 

[Anatomywiz]

This information isn't new-but before you guys go off the deep end and chuck your advil there are more things to concider. Yes both asprin and advil(acetaminophine and ibuprofen) do to some degree inhibit protein synthesis, but one does it approx. 10x more than the other. And the winner(or loser) is asprin, which is good news in a way. Its not an effective antiinflamitory, and in large doses it can cause stomach bleeding, ulcers, etc. Its only good for pain relief. Advil will also slow down protein sythesis and thus muscle recovery, but to a much lesser degree. At a 1000 mg. its also an effective anti-inflammitory, and it doesn't cause gastro-intestinal bleeding. The anti-inflammitory part is the important one for advil, since once you have muscle/tendon/soft tissue swelling there is going to be very little healing happening until the swelling goes down. That's why anti-inflammitories and ice are the athletes friend. This means that although advil may slightly slow down muscle growth, it can more importantly keep slight strains, pains etc. from flairing up into total workout stopping ones. How many of you guys have been training long term using advil and ice when needed before reading this, and made gains? Like all drugs, there is a proper way to use them, and its easy to abuse them. Asprin is only a pain killer and thus worthless-if you can't deal with the pain of intense training then get out. Injury and strain pain is a different story. you deal with injurys as fast as possible with advil 800-1000 mg once to twice a day and ice 2-3 times a day for 10-20 min. so you can recover and get you ass back in the gym training hard. So basically if your in the habit of just popping asprin or advil cuz it can't hurt-stop. However if you have tendinitis, bursitis, whatever and need advil to keep down swelling so you can train hard, then go for it. I'll look to see if I can find the references on asprin being worse than advil in my free time-I just read that one recently, it's just hard since I'm supposed to be working on my thesis.