I pulled this info from several different threads with a little personal input as well. Hope this helps.
How and when to use Nolva:
Running Nolvadex during your cycle prevents the effects of estrogen in the body. It can aid in preventing edema, gyno, and female pattern fat distribution, all of which might occur when your estrogen levels are too high.
To prevent estrogenic side effects normally 10-20 mg/day are sufficient, a dosage which also keeps low the risk of reducing the effect of simultaneously-taken AS. Nolva does NOT inhibit gains. Arimidex, it is an anti-e. It stops aromatation. Problem is, it will mess up your cholesterol levels.
Arimidex = To Prevent Estrogen Creation
Nolvadex = To Stop Estrogen from Binding
Always start with Arimidex, but have nolvadex on hand.
Nolvadex can and will act as a psuedo-estrogen. Arimidex will keep your aromatose activity down to a minimum. Nolva can take the place for estrogenic activities for cholesterol. Which is good!
You can also wait until you have any signs of gyno and then take Nolvadex 20mg's in the morning and 20mg's in the evening for two weeks and continue to take it at 10mg's per day for the remainder of cycle.
Stacking and Use:
If problems of Gynocomastia or other estrogen related symptoms tend to pop up during a cycle the use of 20-30 mg of Nolvadex or 100 mg of Clomid daily should easily contain the problem, and be used until a few days after the problem subsides. For best results and the least amount of problems upon cessation it is best stacked with Proviron (50 mg) or arimidex (0.5 mg) for this duration as well. Its not advised that these products be ran concomitantly with the steroid for the entire duration of the stack, as this will reduce your gains. Instead cease the usage of anti-estrogens once the problem is contained, and should the problem resurface, simply recommence the use of the products in the same manner as described above.
Once a cycle of steroids is concluded one should always initiate a post-cycle therapy to help bring back natural testosterone as soon as possible. This will help you to retain the mass you gained. How this is done depends highly on the type of steroid used. If only orals were used, therapy should start immediately, even the last day of the stack. If short-acting esters or water-based injectables were used, therapy should commence within 4-7 days after last injection, and if long-acting esters were used then it should commence 1.5 to 2 weeks after the last injection was given. The length of the therapy will vary as well, from 3-5 weeks. The longer acting the product was, the longer therapy should be continued to make sure all suppressive factors are cleared before use of Clomid/Nolvadex is discontinued.
For best results, it is best stacked with HCG (Human Chorionic gonadotrophin), which functions as an LH analog and can help bring testicle size back up. HCG use starts the last week of a cycle, and on from there every 5-6 days (usually 1500-3000 IU) and discontinued 1.5 to weeks prior to the cessation of Nolvadex/clomid. The reason being that HCG itself is also suppressive of natural testosterone and should be out of the body before therapy is over, or it will inhibit natural testicle function. But I can not stress enough that HCG possibly plays a more important role in post-cycle therapy than clomid/Nolvadex. For Clomid and Nolvadex, doses are usually tapered down. Its best to start with 40-50 mg of Nolvadex or 150 mg of Clomid for the first week or the first two weeks, and then finish the program with 20-25 mg of Nolvadex or 100 mg of Clomid for an additional two weeks.