What you're asking, it seems to me, is if you're going to go on a super long test cycle is it safe to take Arimidex during the entire time along with it. I would say that the answer is a cautious yes, because people in cancer treatment programs take it for YEARS on end, just like with Nolva. Those are women though, I would think that you would want to have blood work done to figure out exactly what you're levels are. I would rethink the logic of a really long test cycle, and at least include equal "no juice" rest times in there to prevent HPTA problems.