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geoffgarst
New member
Just wondering if anyone has tried Chrysin ( I guess it is found at Vitamin stores)?
Here is the article:
Chrysin and Daidzein as anti estrogen compounds
--------------------------------------------------------------------------------
Speaking to a plastic surgeon such as Dr. Bruce Nadler, about his thriving male breast reduction practice, you might be curious as to why so many athletes would need breast reduction surgery, a procedure costing in excess of $5000, when so may powerful anti-estrogens exist to prevent the causes of gynocomastia. Dr. Nadler, would explain that it is a combination of ignorance, disbelief, and just plain cheapness on the part of bodybuilders and athletes. I would tend to agree. You see, once you have gyno, there is nothing that can be done to get rid of it, but before you get it, there is plenty that can be done to prevent its formation.
So why don’t athletes use anti-estrogens to keep from getting gyno in the first place? Anti estrogens cost pennies compared to painful breast reduction surgery. Like Dr. Nadler might explain, many bodybuilders are ignorant. They still think that gyno can be reversed once they get it. Or worse still, they begin using steroids or steroid precursors and do not know that gyno even exists. In other words, they start a cycle without educating themselves.
Disbelief is an important reason Dr. Nadler’s business is thriving. Many bodybuilders and athletes believe that it will not happen to them. There is some truth to this thinking. Not all athletes who use steroids and steroid precursors will get gyno. These lucky few can take high testosterone dosages and never develop gynocomastia. But the vast majority of us are not nearly so lucky. You and I can and will develop gyno if we do not take precautions before hand. And the third reason, excess thrift, is probably the main cause of gyno in our community. Rather than spending a little bit today to prevent this terrible development, athletes will try and economize and will refuse to invest in the necessary items that can prevent gyno in the first place. You know the old saying, “Penny wise, pound foolish.” Fortunately, there are some excellent drugs and nutriceuticals available both with and without a prescription that can prevent gynocomastia. There are many different types of flavonoids with varying biological activities. What a great number of flavonoids have in common is their ability to selectively inhibit certain enzymes. Our discussion begins with the flavonoids and their ability to block the process of the aromatase enzyme, which is responsible for estrogen conversion in men. Epidemiological studies show that populations in Asian countries have a lesser risk of the hormone-dependant cancers of the breast and prostate than do populations in the West. Among the multitude of environmental and genetic differences between Eastern and Western populations, interest has focused on Asian consumption of food products that are rich in Daidzein. A phytoestrogen is a plant compound that mimics the actions of the animal sex hormone estrogen. Daidzein weakly imitates the actions of estrogen, and, by mechanisms still under investigation, lowers blood sex hormone levels by reducing estrogen and progesterone synthesis. Lowered hormone levels lead to lowered risk of hormone-dependant cancers and more importantly for you and me, a means of preventing gynocomastia. The potent phyto-estrogen Daidzein is a key isoflavone found in soy, and is structurally a very weak "pseudo-estrogen" (about 1000 times weaker than the body's primary estrogen estradiol). This is good news to the bodybuilder because weak estrogens like Daidzein will compete with stronger estrogens like estradiol for available receptor sites to "bind" to. By binding to the receptor sites Daidzein then "blocks" the stronger estrogens from binding to and activating receptor sites. With the Daidzein isoflavone attached, estrogen receptor sites remain inactive. This inactivity further minimizes the negative effects of estrogen in the body. A recent study at the Nanjing Dept. of Veterinary Medicine, looked at the effects of Diadzein administration on muscle growth and hormone levels in lab rats. The study used 66 rats (28 male, 12 female, and 26 castrated male), all 50 days old. (1.) The researchers administered the Diadzein for 16 days continuously. All the rats were fed the same diet. In the male rats who received Diadzein, lean body weight gain increased 14.7% over the control group who did not receive supplemental Diadzein. Serum testosterone, Beta-endorphin and growth hormone all increased as well. In the castrated male rats, no considerable differences were found in body weight gain and hind leg muscle weight, although concentrations of serum growth hormone, Beta-endorphin and testosterone increased significantly. However, the testosterone level of castrated male rats was still only about 8.0% of that of intact male rats. Interestingly, in the female rats, estradiol (Estrogen) decreased significantly.
Another powerful anti-estrogen can be extracted from the Passiflora Caerulea plant. The flavonoid that is extracted is called Chrysin. Research has shown that Chrysin can help block the body from converting testosterone into estrogen. Since most bodybuilders and many athletes are interested in elevating their testosterone levels with supplementation, Chrysin is an ideal supplement to take in conjunction with other testosterone boosters in order to prevent feminizing side effects. Chrysin is a flavonoid recognized as being the most powerful naturally occurring anti-estrogen available today. In fact, Chrysin is as potent as the respected anti-estrogen drug aminogluthemide.
Scientific studies in Europe show that Chrysin has the potential to increase testosterone concentrations in excess of 30% (and have the concentrations REMAIN as testosterone). The late steroid guru Dan Duchaine, referred to Chrysin as "Flavone X" in a May 1996 article in Muscle Media magazine entitled "Flavone X: The next frontier in drug-free muscle building!". Dan described Chrysin as a powerful anti-estrogen testosterone booster. The article's glowing praise of the unnamed flavone created quite a stir in the bodybuilding community and everyone wanted to know which of the flavones was this mysterious "Flavone X." Why did Dan see the need for secrecy? Probably because the supplement company EAS was in the process of applying for a use patent on the flavone which would have given them exclusive rights to sell the most powerful, naturally-occurring anti-estrogen ever discovered at a huge profit. However, someone in their organization leaked the name of the flavone, and the world found out that the mysterious "Flavone X" was actually a flavonoid called Chrysin.In the article, Dan wrote "The following information may be some of the most important writing I've ever done. Its applications will profoundly influence a man's body from puberty until death. By manipulating naturally occurring estrogen in the male metabolism, an individual will allow greater height gains during adolescence, raise testosterone production to 30% over normal, and postpone the declining testosterone secretion that occurs from middle age onward..."
Dan went on to explain the Hypothalamic-Pituitary-Gonadal Axis in detail and describes the dangers of aromatization or testosterone to estrogen conversion in bodybuilders. Dan then states that Chrysin will inhibit aromatase and that most men will experience an increase of at least 20% over normal testosterone levels. European Olympic athletes consume 1-3 grams of Chrysin daily and have found it both safe and effective.
HOW CHRYSIN WORKS
The flavonoid Chrysin works to boost and preserve testosterone in two ways. First through its anti-aromatase function and second by eliminating estrogen's negative feedback loop. Aromatase or estrogen synthetase is what is known as the conversion of testosterone into estrogen through the aromatase enzyme. Chrysin blocks the aromatase enzyme from converting testosterone into estrogen allowing testosterone levels to remain high. By stopping the aromatization of testosterone into estrogen Chrysin also encourages your body to produce more testosterone by eliminating the so-called "negative feedback" loop that would otherwise signal your body to stop or slow natural testosterone production. Your body uses estrogen levels as a sort of test to decide how much testosterone to produce. High estrogen levels means the testes will slow down or stop the production of testosterone. Low estrogen levels means it is time to turn up testosterone production. So, by reducing estrogen levels, Chrysin fools the testes into producing more of mother nature's favorite anabolic hormone-TESTOSTERONE. The elimination of the negative feedback loop, together with Chrysin's anti-aromatase testosterone sparing effect, makes it doubly effective as a testosterone booster.
Research suggests Chrysin’s anti-aromatase function prevents the estrogenic side effects so often associated with the use of androgenic steroids and heavy doses of some steroid precursors. High estrogen levels are commonly associated with androgenic drug and supplement use. Excess testosterone is quickly converted to estrogen via the aromatase enzyme. This excess estrogen can adversely affect the physique by causing gynocomastia, the growth of breast tissue in males —remember, you don't want this to happen because it usually takes surgery to fix. Estrogen also increases water retention under the skin giving you a soft, flat look.
Aside from it’s testosterone increasing and estrogen-suppressing effects, Chrysin has some additional beneficial properties. Chrysin is a potent antioxidant that possesses vitamin-like effects in the body. Additionally, it has been shown to be an anti-inflammatory. Chrysin has one other property that could add to its libido-enhancing potential. A major cause of sexual dissatisfaction among men is work-related stress and anxiety as well as "sexual performance anxiety" that prevents them from being able to achieve erections when they are expected to. Chrysin was shown to produce anti-anxiety effects comparable with diazepam, but without sedation and muscle relaxation. In other words, Chrysin produced a relaxing effect in the brain, but with no impairment of motor activity.
So, you may be wondering, are there any disadvantages to Diadzein and Chrysin, two non-hormonal, anabolic, estrogen suppressing agents. There are no side effects, except that large dosages of each are required for them to be effective.
In summary Chrysin suppresses estrogen, and Diadzein binds to the estrogen receptors (located in abundance around the breast) and then blocks estrogen from attaching itself -- preventing gynocomastia.
Even the most hardcore steroid using bodybuilders, who would previously only have looked toward prescription drugs for relief of estrogenic side effects, may find Chrysin to be a powerfully effective option. Many use it by itself and some stack it with pharmaceuticals to make double certain they avoid gyno.
References:
1. EFFECTS OF DAIDZEIN ON MUSCLE GROWTH AND SOME ENDOGENOUS HORMONE LEVELS IN RATS
J. Wang and Z. K. Han
Dept. of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095 P.R. China.
PS: KARMA IS ALWAYS WELCOME HERE!
So, has anyone tried Chrysin?
Here is the article:
Chrysin and Daidzein as anti estrogen compounds
--------------------------------------------------------------------------------
Speaking to a plastic surgeon such as Dr. Bruce Nadler, about his thriving male breast reduction practice, you might be curious as to why so many athletes would need breast reduction surgery, a procedure costing in excess of $5000, when so may powerful anti-estrogens exist to prevent the causes of gynocomastia. Dr. Nadler, would explain that it is a combination of ignorance, disbelief, and just plain cheapness on the part of bodybuilders and athletes. I would tend to agree. You see, once you have gyno, there is nothing that can be done to get rid of it, but before you get it, there is plenty that can be done to prevent its formation.
So why don’t athletes use anti-estrogens to keep from getting gyno in the first place? Anti estrogens cost pennies compared to painful breast reduction surgery. Like Dr. Nadler might explain, many bodybuilders are ignorant. They still think that gyno can be reversed once they get it. Or worse still, they begin using steroids or steroid precursors and do not know that gyno even exists. In other words, they start a cycle without educating themselves.
Disbelief is an important reason Dr. Nadler’s business is thriving. Many bodybuilders and athletes believe that it will not happen to them. There is some truth to this thinking. Not all athletes who use steroids and steroid precursors will get gyno. These lucky few can take high testosterone dosages and never develop gynocomastia. But the vast majority of us are not nearly so lucky. You and I can and will develop gyno if we do not take precautions before hand. And the third reason, excess thrift, is probably the main cause of gyno in our community. Rather than spending a little bit today to prevent this terrible development, athletes will try and economize and will refuse to invest in the necessary items that can prevent gyno in the first place. You know the old saying, “Penny wise, pound foolish.” Fortunately, there are some excellent drugs and nutriceuticals available both with and without a prescription that can prevent gynocomastia. There are many different types of flavonoids with varying biological activities. What a great number of flavonoids have in common is their ability to selectively inhibit certain enzymes. Our discussion begins with the flavonoids and their ability to block the process of the aromatase enzyme, which is responsible for estrogen conversion in men. Epidemiological studies show that populations in Asian countries have a lesser risk of the hormone-dependant cancers of the breast and prostate than do populations in the West. Among the multitude of environmental and genetic differences between Eastern and Western populations, interest has focused on Asian consumption of food products that are rich in Daidzein. A phytoestrogen is a plant compound that mimics the actions of the animal sex hormone estrogen. Daidzein weakly imitates the actions of estrogen, and, by mechanisms still under investigation, lowers blood sex hormone levels by reducing estrogen and progesterone synthesis. Lowered hormone levels lead to lowered risk of hormone-dependant cancers and more importantly for you and me, a means of preventing gynocomastia. The potent phyto-estrogen Daidzein is a key isoflavone found in soy, and is structurally a very weak "pseudo-estrogen" (about 1000 times weaker than the body's primary estrogen estradiol). This is good news to the bodybuilder because weak estrogens like Daidzein will compete with stronger estrogens like estradiol for available receptor sites to "bind" to. By binding to the receptor sites Daidzein then "blocks" the stronger estrogens from binding to and activating receptor sites. With the Daidzein isoflavone attached, estrogen receptor sites remain inactive. This inactivity further minimizes the negative effects of estrogen in the body. A recent study at the Nanjing Dept. of Veterinary Medicine, looked at the effects of Diadzein administration on muscle growth and hormone levels in lab rats. The study used 66 rats (28 male, 12 female, and 26 castrated male), all 50 days old. (1.) The researchers administered the Diadzein for 16 days continuously. All the rats were fed the same diet. In the male rats who received Diadzein, lean body weight gain increased 14.7% over the control group who did not receive supplemental Diadzein. Serum testosterone, Beta-endorphin and growth hormone all increased as well. In the castrated male rats, no considerable differences were found in body weight gain and hind leg muscle weight, although concentrations of serum growth hormone, Beta-endorphin and testosterone increased significantly. However, the testosterone level of castrated male rats was still only about 8.0% of that of intact male rats. Interestingly, in the female rats, estradiol (Estrogen) decreased significantly.
Another powerful anti-estrogen can be extracted from the Passiflora Caerulea plant. The flavonoid that is extracted is called Chrysin. Research has shown that Chrysin can help block the body from converting testosterone into estrogen. Since most bodybuilders and many athletes are interested in elevating their testosterone levels with supplementation, Chrysin is an ideal supplement to take in conjunction with other testosterone boosters in order to prevent feminizing side effects. Chrysin is a flavonoid recognized as being the most powerful naturally occurring anti-estrogen available today. In fact, Chrysin is as potent as the respected anti-estrogen drug aminogluthemide.
Scientific studies in Europe show that Chrysin has the potential to increase testosterone concentrations in excess of 30% (and have the concentrations REMAIN as testosterone). The late steroid guru Dan Duchaine, referred to Chrysin as "Flavone X" in a May 1996 article in Muscle Media magazine entitled "Flavone X: The next frontier in drug-free muscle building!". Dan described Chrysin as a powerful anti-estrogen testosterone booster. The article's glowing praise of the unnamed flavone created quite a stir in the bodybuilding community and everyone wanted to know which of the flavones was this mysterious "Flavone X." Why did Dan see the need for secrecy? Probably because the supplement company EAS was in the process of applying for a use patent on the flavone which would have given them exclusive rights to sell the most powerful, naturally-occurring anti-estrogen ever discovered at a huge profit. However, someone in their organization leaked the name of the flavone, and the world found out that the mysterious "Flavone X" was actually a flavonoid called Chrysin.In the article, Dan wrote "The following information may be some of the most important writing I've ever done. Its applications will profoundly influence a man's body from puberty until death. By manipulating naturally occurring estrogen in the male metabolism, an individual will allow greater height gains during adolescence, raise testosterone production to 30% over normal, and postpone the declining testosterone secretion that occurs from middle age onward..."
Dan went on to explain the Hypothalamic-Pituitary-Gonadal Axis in detail and describes the dangers of aromatization or testosterone to estrogen conversion in bodybuilders. Dan then states that Chrysin will inhibit aromatase and that most men will experience an increase of at least 20% over normal testosterone levels. European Olympic athletes consume 1-3 grams of Chrysin daily and have found it both safe and effective.
HOW CHRYSIN WORKS
The flavonoid Chrysin works to boost and preserve testosterone in two ways. First through its anti-aromatase function and second by eliminating estrogen's negative feedback loop. Aromatase or estrogen synthetase is what is known as the conversion of testosterone into estrogen through the aromatase enzyme. Chrysin blocks the aromatase enzyme from converting testosterone into estrogen allowing testosterone levels to remain high. By stopping the aromatization of testosterone into estrogen Chrysin also encourages your body to produce more testosterone by eliminating the so-called "negative feedback" loop that would otherwise signal your body to stop or slow natural testosterone production. Your body uses estrogen levels as a sort of test to decide how much testosterone to produce. High estrogen levels means the testes will slow down or stop the production of testosterone. Low estrogen levels means it is time to turn up testosterone production. So, by reducing estrogen levels, Chrysin fools the testes into producing more of mother nature's favorite anabolic hormone-TESTOSTERONE. The elimination of the negative feedback loop, together with Chrysin's anti-aromatase testosterone sparing effect, makes it doubly effective as a testosterone booster.
Research suggests Chrysin’s anti-aromatase function prevents the estrogenic side effects so often associated with the use of androgenic steroids and heavy doses of some steroid precursors. High estrogen levels are commonly associated with androgenic drug and supplement use. Excess testosterone is quickly converted to estrogen via the aromatase enzyme. This excess estrogen can adversely affect the physique by causing gynocomastia, the growth of breast tissue in males —remember, you don't want this to happen because it usually takes surgery to fix. Estrogen also increases water retention under the skin giving you a soft, flat look.
Aside from it’s testosterone increasing and estrogen-suppressing effects, Chrysin has some additional beneficial properties. Chrysin is a potent antioxidant that possesses vitamin-like effects in the body. Additionally, it has been shown to be an anti-inflammatory. Chrysin has one other property that could add to its libido-enhancing potential. A major cause of sexual dissatisfaction among men is work-related stress and anxiety as well as "sexual performance anxiety" that prevents them from being able to achieve erections when they are expected to. Chrysin was shown to produce anti-anxiety effects comparable with diazepam, but without sedation and muscle relaxation. In other words, Chrysin produced a relaxing effect in the brain, but with no impairment of motor activity.
So, you may be wondering, are there any disadvantages to Diadzein and Chrysin, two non-hormonal, anabolic, estrogen suppressing agents. There are no side effects, except that large dosages of each are required for them to be effective.
In summary Chrysin suppresses estrogen, and Diadzein binds to the estrogen receptors (located in abundance around the breast) and then blocks estrogen from attaching itself -- preventing gynocomastia.
Even the most hardcore steroid using bodybuilders, who would previously only have looked toward prescription drugs for relief of estrogenic side effects, may find Chrysin to be a powerfully effective option. Many use it by itself and some stack it with pharmaceuticals to make double certain they avoid gyno.
References:
1. EFFECTS OF DAIDZEIN ON MUSCLE GROWTH AND SOME ENDOGENOUS HORMONE LEVELS IN RATS
J. Wang and Z. K. Han
Dept. of Veterinary Medicine, Nanjing Agricultural University, Nanjing, 210095 P.R. China.
PS: KARMA IS ALWAYS WELCOME HERE!
So, has anyone tried Chrysin?
