Acne all you need to know.

[ryker77]

DOXYCYCLINE

DOXYCYCLINE
Company
Various

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Doxycycline

Available as
Doxycycline (as hyclate) 50mg, 100mg
capsules or 100mg tablets

Indications
Adjunct in severe acne.

Adults
100 mg every 12 hours for first day, then 100mg daily in 1 or 2 divided doses. Reduce dose after improvement.
Take with fluids.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Monitor blood, renal and hepatic function in long-term use.
Avoid sun and UV light. Asthma (syrup).
Pregnancy (Category D), Nursing mothers: Not recommended.

Interactions
May increase digoxin levels. Antacids, iron, zinc, calcium, magnesium, urinary alkalinizers reduce absorption.
Avoid concomitant penicillins, methoxyflurane.
Carbamazepine, hydantoins may decrease effectiveness.
Monitor prothrombin time with oral anticoagulants.
Oral contraceptives may be less effective.

Adverse Reactions
Superinfection, photosensitivity, GI upset, enterocolitis, rash, blood dyscrasias, hepatotoxicity.

How Supplied
Caps: 50mg–50, 100
100mg–50, 100
Tabs: 100mg–50, 200

 

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EMGEL

EMGEL
Company
Elan

Pharmacologic Class
Macrolide antibiotic.

Generic Name
Erythromycin

Available as
Erythromycin 2%, alcohol 77%; gel

Indications
Acne vulgaris.

Adults
Apply sparingly to cleansed dry area as thin layer twice daily (AM & PM).
Wash hands after application.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes, mucous membranes. Reevaluate if no improvement after 8 weeks. Pregnancy (Category B). Nursing mothers: Not recommended.

Interactions
Possible additive irritation with other topical acne agents
(esp. abrasives or keratolytics).

Adverse Reactions
Superinfection, burning, peeling, dryness, pruritus, erythema, oiliness, urticaria.

How Supplied
Gel–27g, 50g

 

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ERYCETTE

ERYCETTE

Company
Ortho Dermatological

Pharmacologic Class
Macrolide antibiotic.

Generic Name
Erythromycin

Available as
Erythromycin 2%, alcohol 66%; saturated swabs.

Indications
Acne vulgaris.

Adults
Rub over cleansed area twice daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes, nose, mouth, and mucous membranes.
Pregnancy (Category C). Nursing mothers.

Interactions
Additive irritation with other topical agents (esp. abrasives or keratolytics).

Adverse Reactions
Superinfection, dryness, scaly skin, pruritus, burning sensation.

How Supplied
Swabs–60

 

[ryker77]

ERYTHROMYCIN TOPICAL

ERYTHROMYCIN TOPICAL

Company
Various

Pharmacologic Class
Macrolide antibiotic.

Generic Name
Erythromycin

Available as
Erythromycin 2%, topical solution, gel.

Indications
Acne vulgaris.

Adults
Apply with applicator or pad to cleansed area twice daily.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication.

Precautions
Avoid eyes and mucous membranes. Pregnancy (Category B).
Nursing mothers: Not recommended.

Interactions
Additive irritation with other topical agents (especially abrasives or keratolytics).

Adverse Reactions
Superinfection, dryness, scaly skin, pruritus, urticaria, erythema,
oiliness, burning sensation.

How Supplied
Soln–60mL
Gel–30g, 60g

 

[ryker77]

FINEVIN

FINEVIN

Company
Berlex

Pharmacologic Class
Antibacterial - keratolytic.

Generic Name
Azelaic acid

Available as
Azelaic acid 20%; cream

Indications
Mild to moderate inflammatory acne vulgaris.

Adults
Wash and dry skin. Massage thin film gently into affected areas twice daily (AM and PM). Wash hands after use. If persistent irritation occurs, reduce to once daily.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication.

Precautions
Monitor patients with dark complexions for hypopigmentation. Discontinue if sensitivity or severe irritation develops. Avoid mouth, eyes, other mucous membranes, and occlusive dressings. Pregnancy (Category B). Nursing mothers.

Adverse Reactions
Pruritus, burning, stinging, tingling; rare: exacerbation of asthma or of recurrent herpes labialis, vitiligo depigmentation, small depigmented spots, hypertrichosis, reddening.

How Supplied
Cream—30g

 

[ryker77]

KLARON

KLARON

Company
Dermik

Pharmacologic Class
Sulfonamide antibiotic.

Generic Name
Sulfacetamide

Available as
Sodium sulfacetamide 10%; lotion.

Indications
Acne vulgaris.

Adults
Apply thin film twice daily to affected areas.

Children
Not recommended.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication

Precautions
Discontinue if hypersensitivity, skin rash, or irritation occur. Avoid eyes.
Denuded or abraded skin. Asthma. Pregnancy (Category C). Nursing mothers.

Adverse Reactions
Local irritation; severe systemic toxic reactions to sulfonamides
may occur rarely.

How Supplied
Lotion–2oz

 

[ryker77]

MINOCIN

MINOCIN

Company
Wyeth

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Minocycline

Available as
MINOCIN CAPSULE
(Minocycline (as HCl) 50mg, 100mg; pellet-filled capsules)
MINOCIN SUSPENSION
(Minocycline (as HCl) 50mg/5mL; custard flavored; contains sulfites and alcohol 5%)

Indications
Adjunct in severe acne resistant to tetracycline and erythromycin.

Adults
Initially 50-200mg daily in 2 divided doses. Reduce dosage after improvement. Take with fluid.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in its class, to related drugs, or to any of its excipients, is assumed to be a contraindication

Precautions
Renal impairment. Asthma (susp). Monitor blood, renal and hepatic function in long-term use. Pregnancy, Nursing mothers: Not recommended.

Interactions
May increase digoxin levels. Antacids, iron, zinc, calcium, magnesium, urinary alkalinizers reduce absorption.
Avoid concomitant penicillins, methoxyflurane.
Monitor prothrombin time with oral anticoagulants.
Oral contraceptives may be less effective.

Adverse Reactions
Nausea, dizziness, rash, blood dyscrasias, pseudotumor cerebri, photosensitivity (rare), increased BUN, hepatotoxicity.

How Supplied
Caps: 50mg–100, 250
100mg–50, 250
Susp–2oz

 

[ryker77]

MINOCYCLINE

MINOCYCLINE
Company
Various

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Minocycline

Available as
Minocycline (as HCl) 50mg, 100mg; capsules.

Indications
Adjunct in severe acne resistant to tetracycline and erythromycin.

Adults
Initially 50-200mg daily in 2 divided doses. Reduce dosage after improvement. Take with fluid.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication

Precautions
Renal impairment. Monitor blood, renal and hepatic function in long-term use. Pregnancy, Nursing mothers: Not recommended.

Interactions
May increase digoxin levels. Antacids, iron, zinc, calcium, magnesium, urinary alkalinizers reduce absorption.
Avoid concomitant penicillins, methoxyflurane.
Monitor prothrombin time with oral anticoagulants.
Oral contraceptives may be less effective.

Adverse Reactions
Nausea, dizziness, rash, blood dyscrasias, superinfection, pseudotumor cerebri, photosensitivity (rare), increased BUN, hepatotoxicity.

How Supplied
Caps: 50mg–100
100mg–50

 

[ryker77]

MONODOX

MONODOX
Company
Oclassen

Pharmacologic Class
Tetracycline antibiotic.

Generic Name
Doxycycline

Available as
Doxycycline monohydrate 50mg, 100mg; capsules.

Indications
Adjunct in severe acne.

Adults
200mg in 2-4 divided doses for 1 day, then 100mg/day in 1-2 doses.
Reduce dose after improvement. Take with fluid.

Children
Not applicable.

Contraindications
Although not explicitly stated, hypersensitivity to this drug, to others in
its class, to related drugs, or to any of its excipients, is assumed to be
a contraindication

Precautions
Monitor blood, renal, and hepatic function in long-term use.
Sunlight or UV light. Pregnancy (Category D), Nursing mothers:
Not recommended.

Interactions
May increase digoxin levels. Antacids, iron, zinc, calcium, magnesium reduce absorption.
Avoid concomitant penicillins, methoxyflurane.
Carbamazepine, hydantoins, barbiturates may decrease effectiveness.
Monitor prothrombin time with oral anticoagulants.
Oral contraceptives may be less effective.

Adverse Reactions
Superinfection, photosensitivity, GI upset, enterocolitis, rash, blood dyscrasias, hepatotoxicity.

How Supplied
Caps: 50mg–100
100mg–50, 250

 

[ryker77]

ORTHO TRI-CYCLEN 28

ORTHO TRI-CYCLEN 28 Just for info not for guys.
Company
Ortho-McNeil

Pharmacologic Class
Progestin + estrogen

Generic Name
Ethinyl estradiol + Norgestimate

Available as
Norgestimate 0.18mg, ethinyl estradiol 35micrograms (7 tabs); norgestimate 0.215mg, ethinyl estradiol 35micrograms (7 tabs); norgestimate 0.25mg, ethinyl estradiol 35micrograms (7 tabs);
inert (7 tabs).

Indications
Moderate acne vulgaris in females, ³15 years of age,
who have no known contraindications to oral contraceptive therapy,
desire contraception, have achieved menarche and are unresponsive
to topical anti-acne medications.

Adults
Use Day 1 or Sunday start for the first cycle.
1 tablet daily for 28 days; repeat.

Children
Not applicable.

Contraindications
Thrombophlebitis or thromboembolic disorders. Cerebral vascular or coronary artery disease. Breast or other estrogen-dependent neoplasms. Undiagnosed abnormal genital bleeding. Cholestatic jaundice of pregnancy or jaundice with prior OC use. Hepatic adenoma or carcinoma. Pregnancy (Category X).

Precautions
Smokers over 35 years of age: Not recommended. Uncontrolled hypertension. Hypertriglyceridemia. Discontinue if jaundice, visual disturbances, migraine or other severe headaches occur. Do regular complete physical exams. May need barrier contraception with Sunday starts or postpartum use (see literature). Nursing mothers: Not recommended.

Interactions
Antagonized by hepatic enzyme inducing drugs (eg, rifampin, carbamazepine, St. John's wort), possibly others. May affect measurement of sex hormone-binding globulin levels.

Adverse Reactions
Hypertension, nausea, vomiting, breakthrough bleeding, amenorrhea, transient delay of ovulation after discontinuation, edema, chloasma, mastodynia, headache, intolerance to contact lenses. Increased risk of gallbladder disease, thromboembolic disorders.

How Supplied
Packs–1