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1-tu

JBRIII

New member
Has anyone experienced total HPTA shutdown after Nutrex 1-Tu useage? It has been 4 months and i have still not recovered and my Dr. is putting me on HRT.

Just wondered if anyone else had this issue?
 
1-test is extremely suppressive of the HPTA.. why exactly?? though it may be a progestinic agonist or antagonist (which tend to be very suppressive)
 
Macrophage,

What evidence do you have that 1-test is suppressive?

Also, why do you think 1-test may be a progestenic agonist or antagonist?

Also (and I know it sounds dumb), what really is an agonist / antagonist?

Thank you,


Singleton
 
numerous reports, from previous PH users, of extended psot cycle blues, weakness, lethargy and sexual impotence.

because it does not aromatize, and yet there are reports of gyno and in particular puffy nipples, it is likely due to progestenic agonism.

agonists activate the receptor (though not necessarily like the natural hormone)
antagonists sit in front of the receptor "blocking it" and doing little or nothing (though there are some variances here)

because it does not aromatize, its suppression of the HPTA is most likely due to PR activity (steroids are typically mixed agonist/antagonists.. like the serms clomid and nolva)
 
OK. I'm interested because I used 1-test and got some sides.

I got puffy nipples. The left one even leaked a bit :eek2:. I only ran it for 2 weeks. My balls got a little smaller, but came back in an equal amount of time.

Also, I felt like a pussy when on it. Killed my aggression dead.

Based on the nipple problem, it seems that it had activated my progesterone receptors. What makes you think it blocks progesterone receptors? Is it that in blocking progesterone receptors, the body overcompensates by producing more progesterone?
 
Singleton said:


Based on the nipple problem, it seems that it had activated my progesterone receptors. What makes you think it blocks progesterone receptors? Is it that in blocking progesterone receptors, the body overcompensates by producing more progesterone?

it probably does both (as do many synthetic hormones).. the "hardness and dryness" that some experience as well as joint pain are indicative of PR antagonism and the leaking nipple due to agonism of the PR in that tissue as well as in the HPTA (increasing prolactin)
 
Update

As an update it's been approximately 5 months since I last used
1-TU and I have still not recovered, my level was 168. My Doc finally put me on Testim gel. It's only been 4 days, but I'm feeling much better. Going back in a few weeks for a re-check to make sure the dosage is correct.
 
JBRIII - Sorry to hear that.

Did your balls come back to normal size yet?

If not, then use HCG.

Otherwise:
* intense exercise, especially in mid-morning - increases test
* Bright sunlight in the morning - stimulates LH production
* Avena Sativa - works (by freeing bound T?)
* 8 hours sleep

Mac - All of my bones hurt, even my skull, if you can believe that! 1-test was awful. Surpressed my natural test production, but I did get supranormal pumps from it.

Wort thing was the prostate problem, which could have been a good thing. Made me see a doc and now I'm on Cipro. Although 1-test may have aggrivated my prostate, I may have had a preexisting case of prostatitus that was further aggrivated by the androgen. If I hadn't taken 1-test, I would have lived with the minor symptoms. While on 1-test, I just could NOT hold my piss and this was way WAY uncool. The symptoms on 1-test drove me see a doctor.

I still don't know what to do with the rest of the bottle, but I know there are some who like this stuff. Hoping someone will buy it off me and help spare me some of the loss.
 
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