no receptor site=more steroids or quit steroids?

[mhb3939]

With that cycle.... Sounds like the gear to me also....

 

[southeastar]

dam dont feel bad, im only 25, and got my shit from an eckerds pharmacy, so i know its real..it made by watsonphareceuticals and their web site has the same exact pics of gear as the ones i have, same numbers on labels etc..i wish they were fake then atleast i would have some hope..but i donr

bro test your gear on a lab and u will definally know the truth.

 

[Whacked]

Receptor sites??? Steroid's are nonpolar molecules, which freely diffusion through the plasma membrane of cells with no need for "receptor sites" or plasma membrane receptors required to bring them into the cell. There are NO "receptor sites" for steroid molecules. There are steroid molecule receptors inside, the cells, which when in complex with the steroid will bind and activate transcription (or protein synsthesis).

nautica

With all due respect, that's splitting hairs and misinformation IMO. Call it a semantics game here but there are in fact receptor "sites". Every hormone in the body (insulin, cortisol, testosterone, estrogen, etc..) has "receptor site" it communicates with!

"Steroid hormones work by stimulation of receptor molecules in muscle cells, which activate specific genes to produce proteins (see Figure 1). They also affect the activation rate of enzyme systems involved in protein metabolism, thus enhancing protein synthesis and inhibiting protein degradation (called an anti-catabolic effect). Heavy resistance training seems to be necessary for anabolic steroids to exert any beneficial effect on physical performance. Most research studies that have demonstrated improved performance with anabolic steroids used experienced weight lifters who were capable of training with heavier weights and producing relatively greater muscle tension during exercise than novice subjects. The effectiveness of anabolic steroids is dependent upon unbound receptor sites in muscle. Intense strength training may increase the number of unbound receptor sites. This would increase the effectiveness of anabolic steroids."


References
American Medical Association, Council on Scientific Affairs. Medical and non-medical uses of anabolic-androgenic steroids. J. Amer. Med. Assoc. 264: 2923-2927, 1990.

Bahrke, M.S., C.E. Yesalosk, and J.E. Wright. Psychological and behavioural effects of endogenous testosterone levels and anabolic-androgenic steroids among males: a review. Sports Med. 10: 303-337, 1990.

Buckley, W.E., C.E. Yasalis, K.E. Friedl, W.A. Anderson, A.L. Streit, and J.E. Wright. Estimated prevalance of anabolic steroid use among male high school seniors. J. Amer. Med. Assoc. 260: 3441-3445, 1988.

Rogozkin, V. Metabolism of Anabolic Androgenic Steroids. Leningrad: Nauka, 1988.

United States Olympic Committee. USOC Drug Education Handbook. Colorado Springs: USOC, 1989.

 

[Whacked]

Maybe you're one of these people that needs high-dosed gear cycles. Talk to Needsize. He's a VET here who always says he uses more gear than the next guy to get comparable results.

How's your training? Some people feel the need to over-train while on gear. This alone can be more catabolic than anything.

Do you have a high metabolism? Maybe you need EVEN more?

Do you do a ton of cardio?

Do you get adequate rest/sleep?

How's your thyroid? Have you abused dieting in the past?

How is your macronutrient ratio? Some respond better to high carb/moderate/low fat protein -- while others respond to high protein/moderate carbs/moderate healthy fat intake.

Maybe you just don't respond well to these particular drugs. Referring to Needsize again, he doesn't like (or respond to) Test. I believe he says he doesn't repond to Test but does very well on other drugs. Perhaps -- that's the case with the drugs you chose. I have to believe sine you gained "some weight" albeit minimal for that cycles, your body DOES have the ability to "respond" to gear.

There are plenty of other correlating/obstructing factors it could be.

Dissect your lifestyle, eating habits, training habits and investigate what gear works for YOU -- that's what the game is all about -- a marathon, not a sprint.

Good luck.

 

[sixfoot2whiteboy]

my diet is was on point, not to brag but i did everything right, from 10 hours slep a night to lifting how i need to grow, just doesnt happen for me..as far as cardio i dont do it cause i do have a faster metab ( i could eat wendys 4 times a day for a year and not get fat,lol,even tho i dont) and not a like im a strength freak or anything but i was repping 315 for 12 reps etc and bench 275 for 10 reps so the strength to grow was there, i just dont know im at the end of my rope...

 

[PolfaJelfa]

i call bs on this whole receptor garbage

 

[Goldprospector]

I agree with everyone who says the "receptor site" nosense is BS! I could be a numvber of issues and the # 1 is prolly fake gear.
But there is another thing to consider...everyone is different and there cannot be a comparison of gains from one person to the next...there are just too many variables.
I don't know what you genetics are like, but if you are anywhere close to your genetic limit...or over it, then it will always take "MORE AMOUNT OF GEAR" to keep growing. Anyone who is far from reaching there genetic limits can grow on minimal amounts of gear...it may not be much...but it will be there.

So just switch the gear and/or source and adjust the amounts to fit your body...It usually takes several cycles to find the right amounts and the right gear for you personal profile.

 

[PolfaJelfa]

Everyone is different I agree. Some need 1 gram to grow some need 100mg. Some are 300 lbs shredded on genetics alone. Look at that little muscle freak-world record kid. Now..what i mean about receptor bs is results are the same after x ammount of years. Same deal. Obviously if you are already 250lbs+ you will not keep puting on the same mass as you did to get from 150 to 160. This has nothing to do with receptors. Imo

 

[debo0211]

you got fucked with the gear, I would'nt give a damn if it was my GRANPAPPY, who gave it to me, GET IT TESTED!! AL WAYS GET YOUR GEAR TESTED

 

[PolfaJelfa]

I will tell you its most likely one of two things.

1. Your gear is bad.

2. Its all in your head.

also option 3 of training/rest/eating improperly